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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Although multiple studies have investigated the biomarkers of response to immune checkpoint blockade...
We present the set of gene expression in in H2122 cells with transfection of control shRNA vs H2122 ...
We want to investigate the transcriptional differences between pBABE D4m.3a melanoma cells (cancer c...
We studied the role of the histone methyltransferase DOT1L in B cell development and differentiation...
The Calcium-Sensing receptor (CaSR) is a G proteins-coupled receptor involved in calcium homeostasis...
In this study, we focused on understanding the effect of the functional inactivation of the caspase ...
Epigenetic modifications, including DNA methylation and histone modifications, are reprogrammed cons...
Growth factor, TGF beta can have profound effect on global gene expression changes. Since TGF beta s...
Cancer stem cells (CSCs) have been proposed to underlie the hierarchical organization of Glioblastom...
The differentiation of nave CD4+ T cells into T helper (Th) subsets is key for a functional immune r...
Purpose: Investigate the transcriptomic landscape throughout the time course of murine digit regener...
Genome-wide association studies (GWAS) have reported hundreds of genomic loci associated with schizo...
Gene expression is finely regulated during development, and deregulation can lead to disease. In ped...
The aim of this study was to analyse the whole transcriptome profile of medial prefrontal cortex of ...
Endometrial estrogen receptor- (ESR1) is indispensable for epithelial and stromal proliferation and ...
Heterozygous PAX6 gene mutations leading to haploinsufficiency are the main cause of congenital anir...
bulk RNA-seq of wild-type, Gli2f/f;Gli3f/f;Wnt1-Cre, and Hand2f/f;Wnt1-Cre mouse e10.5 dissection ma...
ObjectiveOverexpression or administration of sclerostin has been reported to have atheroprotective a...
Purpose: To test the role of Myc in adaptive expansion of beta cells; Methods: Islets were isolated ...
Uterine leiomyomas (LM) affect up to 80% of all reproductive-age women. LM growth requires progester...
iPSC derived microglial precursors were transplanted into the brains of neonatal mice, FACS sorted o...
Embryonic stem cells (ESCs) can exist in at least two states that transcriptionally resemble differe...
RNA-seq performed in ATF7ip-deficient T cells reveals a defect in Th17 gene induction secondary to i...
Cardiac transdifferentiation represents an attractive way of reversing heart damage caused by myocar...
Homoeothermic organisms maintain their core body temperature in a narrow, tightly controlled range. ...
NUP98-NSD1 positive Acute myeloid leukemia (AML) frequently occurs within the pediatric karyotypic n...
Despite recent advances in genomic profiling techniques, the precise mechanisms controlling GBM subt...
To determine the transcriptional responses to heat shock of inner ear sensory hair cells and support...
Effects of Zika virus (ZIKV) infection on placental development during pregnancy are unclear. In thi...
The deubiquitinase USP22 is a member of the SAGA transcriptional activation complex. This study used...
Carrying premature termination codons in one allele of the ABCA7 gene is associated with an increase...
The helicase-like transcription factor (HLTF) gene a tumor suppressor in human colorectal cancer (C...
We analyze transcritpional changes upon Max deletion using CRISPR Cas9 SOURCE: Arnaud,A,Augert (aaug...
Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-bindin...
Using mouse mammary epithelial cells as a model system, we investigated the remodeling of zinc homeo...
In mammals, retinal damage is followed by Mller glia cell activation and proliferation. While retina...
we report the changes in the transcriptome of human umbilical vein endothelial cells (HUVECS) after ...
In this study, we show that pediatric T-cell acute lymphoblastic leukemia (T-ALL) has an alternative...
We observed different gene expression by overexpressing the transcription factor FOXP2 in U2OS cells...
The overall goal is to understand how does the DNA methylation Canyon interactions in CD34+ HSPCs ca...
We report the application of single-molecule-based sequencing technology for high-throughput profili...
Recent studies have identified a genetic variant rs641738 near two genes encoding membrane bound O-a...
The Pitx2 gene encodes a homeobox transcription factor that is required for mammalian development. D...
For all but a few mRNAs, the dynamics of metabolism are unknown. Here, we developed an experimental ...
In the current study, we analyse the function of MOF-NSL complex in neural cells. We find that the N...
Slow-cycling/dormant cancer cells (SCCs) are thought to cause cancer relapse, but the underlying bio...
Mitochondrial functions are essential for cell viability and rely on protein import into the organel...
Erythrocyte binding-like (EBL) proteins are known to play an important role in malaria parasite inva...
Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor progn...
Testis-restricted melanoma antigen (MAGE) proteins are frequently hijacked in cancer and play a crit...
We observed an increasing trend of nuclear SLC29A2 expression associated with high histological de-d...
The goal of the RNAseq experiment is to compare gene expression of T cells in different microenviron...
The intestinal epithelium is a paradigm of adult tissue in constant regeneration that is supported b...
Microbeads (experimental glaucoma) or saline solution (controls) were injected into right anterior c...
The differentiation of nave CD4+ T cells into T helper (Th) subsets is key for a functional immune r...
Aim: To assess the effect of IL-26 on mouse colonic tissue at steady state and in DSS-induced coliti...
TRAP translational profiling is a method that allows investigators to genetically characterize speci...
The purpose of this study is to learn the dynamic transcriptomic and molecular changes during neutro...
There are two aims in this study (1) To figure out the pathogenic sub-populations of CD4+ T cells i...
Fusobacterium nucleatum (F. nucleatum) is implicated to exacerbate colorectal cancer. However, there...
Molecules mimicking the active N-terminal tetrapeptide of the second mitochondrial-derived activator...
The study was designed to determine the differential gene expression between burn eschar- and normal...
We report a type 1 interferon response accompanying polyclonal knockout of CNOT1 or CNOT10 in primar...
Damaged tissues have increased risk of cancer development through poorly understood mechanisms. In t...
CRPC remains AR dependent. There are multiple mechanisms for reactivation of AR including expression...
We analyze transcritpional changes upon Max deletion in a mouse model of SCLC driven by Rb and p53 l...
We report that monocytic (mMDSC) and granulocytic (gMDSC) MDSC susbsets have distinct expression pro...
We report bulk RNA-sequencing of bone marrow-derived macrophages (BMDMs) harvested from myeloid-spec...
Oxidative stress is a major pathogenic mechanism in Parkinsons disease (PD). As an important cellula...
The Hippo signalling-dependent co-activator YAP controls organ size by regulating cell proliferation...
GRHL3 is required for epithelial morphogenesis and periderm function SOURCE: Ghaidaa Kashgari (gkas...
Trophoblast stem cells lack MAP3K4 activity (TSKI4 cells) switch from epithelial phenotype to interm...
It is known that granulosa cells (GCs) mediate gonadotropin-induced oocyte meiosis resumption by rel...
We constructed strand-specific cDNA libraries of 8 total RNA samples and sequenced the libraries usi...
It has been shown that hypertrophic chondrocyte (HC) can become osteoblast, contributing to the form...
The enzyme transport vehicle (ETV:IDS) is a lysosomal enzyme fused to iduronate 2-sulfatase (ETV:IDS...
RNA-sequencing demonstrated Acod1 (Aconitate decarboxylase 1) as one of the top genes induced by air...
MicroRNAs (miRNAs) act within Argonaute proteins to guide repression of mRNA targets. Although vario...
Background. Mutations in GNE cause a recessive, adult onset myopathy characterized by slowly progres...
The cyclin-dependent kinase inhibitor p57KIP2 is encoded by the imprinted Cdkn1c locus, exhibits mat...
The goal of this study was to identify differentially expressed genes between pre-vaccination and da...
Early UPR-affiliated gene expression occurs before Blimp1 upregulation and independent of canonical ...
Hepatocyte-specific loss of Slc25a37 (Mitoferrin1) in Mitoferrin2-/- mice did not affect animal viab...
Photoreceptor cell degeneration is a major cause of blindness and a considerable health burden durin...
By substituting lysine 27 in histone variant H3.3 to arginine in mouse embryonic stem cells, we meas...
We found a high frequency of heterozygous Fanconi-BRCA pathway mutations in pediatric T-ALL. BRCA2 ...
To identify changes in splicing patterns following TARBP2 knockdown, RNA-sequencing was performed on...
Gene expression changes in leukemic LKlow cells after depleting nestin+ cells in vivo SOURCE: Manuel...
To test how translational control of proteome quality affects stem cell function, we examined Aarsst...
Background: Dissecting the in-vivo host-pathogen interplay is crucial in understanding the molecular...
We previously had generated clonal mouse melanoma cell lines, where each clone was isolated in a RAF...
Smooth muscle cell TGF signaling is one of the primary drivers of smooth muscle cell maturation. Inh...
Whole lens transcriptome profiling by RNA-seq analysis was performed to investigate the role of S100...
During transcriptional activation, chromatin undergoes structural changes with the help of various p...
to gain insight into how Mcph1 inactivation affected cell cycle progression and survival of neocorti...
Cardiac fibroblasts have a central role during the ventricular remodeling process associated to diff...
Babao Dan has efficient therapeutic effects on patients with pancreatic cancer.However, little is kn...
Sample index hopping refers to the incorrect sample assignment of a demultiplexed sequencing read in...
The development of efficacious therapies targeting metastatic spread of breast cancer to the brain r...
Purpose: One important challenge in the field of Chagas disease research is to determine the main f...