Explore curated data sets and assays
Pluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for access
Sequencing-based assays page 101
Store large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
GSE139003: RNA-seq timecourse of p53 activation with Nutlin-3a in IMR90 cells
To investigate the dynamics of the p53 response, we treated IMR90 cells with Nutlin-3a, a small mole...
GSE141280: SE-driven metabolic reprogramming in ADPKD (RNA-Seq)
Metabolic reprogramming is emerging as a key pathological contributor to the progression of autosoma...
GSE149123: RNAseq for perigonadal WAT of adipose tissue specific CDK7 knockout mice under CL or saline treatment for 7 days.
Purpose: The goal of this study are to compare global gene expression profile in pgWAT in Cdk7 aKO ...
GSE138984: Quantitative analysis of transcriptomes in irradiated/unirradiated pancreatic cancer cells
Irradiated dying tumor cells play crucial roles in tumor repopulation. However, the transcriptome ch...
GSE141328: Serine-threonine Kinase, ROCK2, Regulates Germinal Center B Cell Positioning and Cholesterol Biosynthesis
Splenic follicular B cells (FoB; B220+GL7-CD38hiCD23+) and Germinal Center B cells (GCB; B220+GL7+CD...
GSE155626: Effects of TNFR1 deletion on Il10-/- mouse colitis in early life
The loss of TNFR1 (Tnfrsf1a) in the Il10-/- spontaneous mouse colitis background results in accelera...
GSE101743: LncRNA NMR knockdown and overexpression in esophageal squamous cell carcinoma cell lines
Long noncoding RNAs (lncRNAs) are emerging as key regulators in cancer and play complicate and criti...
GSE152165: Rapamycin and dexamethasone during pregnancy prevents tuberous sclerosis complex associated cystic kidney disease
Chronic kidney disease is the main cause of mortality in patients with tuberous sclerosis complex di...
GSE139010: CircRNA analysis in depolarized neuroblastoma cells
We profiled circRNA using RNA-seq in the depolarized neuroblastoma cells to detect depolarization as...
GSE140964: Pharmacological target focused transcriptomic analysis of native versus cultured human and mouse dorsal root ganglia
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE149099: Transcriptomic comparison of young and aged choroid at the bulk and single-cell levels (bulk)
Purpose: The goals of this study were to identify cell specific expression patterns from infant and ...
GSE132148: Gene expression from mouse models of B cell lymphomagenesis driven by gp130 signaling
This study examines the transcriptional changes invoked by activation of gp130 signaling in differen...
GSE152226: EDMD-causing emerin mutant myogenic progenitors exhibit impaired differentiation using similar mechanisms
RNA sequencing was performed on proliferating and differentiating emerin-null myogenic progenitors e...
GSE140191: Bystander IFN- activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment
The cytokine IFN-g produced by tumor-reactive T cells is a key effector molecule with well character...
GSE132947: HyperTRIBE uncovers MSI2 increased RNA binding activity and differential regulation in leukemic stem cells [LSK cells]
Understanding RBPs molecular functions as well as their cell-type specific activity requires identif...
GSE139016: Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma
RNA-seq analysis was performed to compare gene expression of glioma cells with MLL1 and MLL2 knockdo...
GSE146156: RNA-seq data of TAGAP WT or KO BMDMs treated with Curdlan
Bone marrow derived macrophages (BMDMs) were isolated form WT or TAGAP-KO mice, followed by stimulat...
GSE94493: ChIPseq and RNAseq of ER mutant breast cancer cell lines
We performed several extensive phenotypic, genomic, and transcriptomic analyses in an effort to disc...
GSE155618: Role of PTEN in B-ALL
To elucidate the dependence of B-ALL cells on PTEN we analysed the transcriptional changes upon indu...
GSE99909: Polysome-profiling in small tissue samples - proof of concept experiment for the use of an optimized non linear gradient
Polysome-profiling is commonly used to study translatomes, i.e. transcriptome-wide patterns of trans...
GSE132031: Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression
Metastatic breast cancer is an extremely complex disease with limited treatment options due to the l...
GSE128263: Cadmium exposure induces SNAIL1 expression via downregulation of miR-30e in human bronchial epithelial cells
Purpose: To understand the molecular mechanisms underlying Cd exposure-induced diseases.; Methods: I...
GSE149067: RNA-sequencing of ApoB-reactive CD4+ T cells in mice
We report the transcriptome of atherosclerosis-specific murine CD4+ T cells in atherosclerosis that ...
GSE139310: Regulation of uterine genes during the peri-implantation period, and its relationship to gene expression changes in the maternal brain in gestating mice (RNA-seq)
In this study, we conducted an integrated analysis of gene expression and chromatin structure of mou...
GSE155673: Systems biological assessment of immunity to severe and mild COVID-19 infections
CITE-seq of 7 patients with COVID-19 and 5 healthy controls SOURCE: Madeleine Scott Stanford
GSE139663: HDAC3 maintains oocyte meiosis arrest by repressing amphiregulin expression before the LH surge [HDAC3cKO]
It is known that granulosa cells (GCs) mediate gonadotropin-induced oocyte meiosis resumption by rel...
GSE139836: Single-Cell transcriptomes and immune profiling of IgG+ murine memory B cells from Bone Marrow and Spleen.
Single cell sequencing for analysis gene of gene transcription and Ig repertoires of isotype-switche...
GSE139989: Nuclear Parkin Regulates Transcriptional Response during Hypoxia
Purpose: The E3 ubiquitin ligase Parkin is a well-characterized regulator of mitochondrial autophagy...
GSE132357: RNA methylation maintains hematopoietic stem cell identity and symmetric commitment
Stem cells balance cellular fates through asymmetric and symmetric divisions in order to self-renew ...
GSE139283: RNA-seq Analysis of Kidney versus Splenic CD4+ and CD8+ T cells in MRL/lpr Lupus Mice
Purpose: To understand the differences in gene expression of lupus T cells in secondary lymphoic org...
GSE143912: Transcriptome of wildtype and Meis2 mutant in the developing palate
We useRNA-sequencing to profile the different expression genes in the palatal mesenchyme of wildtype...
GSE128384: RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF)
The goal of this experiment was to identify if there are any genes differentially expressed in flage...
GSE125472: Human colon organoids reveal distinct physiologic and oncogenic Wnt responses
Constitutive Wnt activation upon loss of Adenoma polyposis coli (APC) acts as main driver of colorec...
GSE136750: A Second Heart Field-derived vasculogenic niche contributes to cardiac lymphatics
The mammalian heart contains multiple cell types that appear progressively during embryonic developm...
GSE139960: Wnt/-catenin activation epigenetically reprograms Regulatory T cells in IBD and progression to dysplasia
Previous work indicated that -catenin/TCF-1 occupy DNA together with Foxp3. Thus, we anticipated tha...
GSE141259: Longitudinal single-cell transcriptomics analysis of mouse lung upon bleomycin-induced injury
Two single-cell RNA sequencing data sets were generated called "Whole lung" and "High Resolution". T...
GSE138672: Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration
Rab and associated effector proteins are involved in all steps of cargo transport through subcellula...
GSE139324: Immune landscape of viral- and carcinogen-drived head and neck cancer
Head and neck squamous cell carcinoma (HNSCC) arises through exposure to environmental carcinogens o...
GSE157609: IFI16 functions as an antiviral factor during influenza virus infection by binding viral RNA and enhancing the RIG-I signaling
RIG-I is thought to be the most important sensor of influenza virus infection and plays critical rol...
GSE141268: Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after lipopolysaccharide induced lung inflammation I
While the inflammatory immune response of the lung to allergens and pathogens has been extensively s...
GSE139964: RNA sequencing of Sphk1fl/fl Sphk2-/- and Sphk1-/- Sphk2-/- mESC clones.
We report a growth defect in sphingosine kinase null clones due to a cell cycle arrest in G2/M phase...
GSE148658: SIX6 knockdown in Jurkat-Cas9 T-ALL cell line
T cell acute lymphoblastic leukemia (T-ALL) is a hematological malignancy strongly affected by the a...
GSE141345: A-to-I RNA editing enzyme Adar1 is essential for cardiac morphogenesis
In recent years, the topic of RNA modifications, epitranscriptomics, has gained momentum in a variet...
GSE131680: Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation
We recently described the phenotype of HepG2 and Huh-7, hepatocellular carcinoma cells, knocked down...
GSE135514: Transcriptomic insight into salinomycin mechanisms in breast cancer cell lines: synergistic effects with dasatinib and induction of estrogen receptor beta
Purpose:The use of a single-drug to encounter cancer progression is generally ineffective due to the...
GSE148564: RNA-seq of WT and Stat3 cKO neural progenitors
To identify STAT3-regulated genes during neural progenitor development. SOURCE: Yixun Su (suyixun@u....
GSE141372: Transcriptome wide alternative splicing analysis to determine the effect of CDK12 and CDK13 inhibition by THZ531 in alternative splicing (Total RNA-Seq)
We performed Total RNA-seq on MV4;11 cells after 6 hours treatment of THZ531 to determine whether CD...
GSE143880: Next Generation Sequencing Analysis of Transcriptomes of the HEK293T-Cas9 cells transfected with plasmid containing programmed scaffold RNA
By performing RNA sequencing (RNA-seq) analysis on the HEK293T-Cas9 cells which transfected with pla...
GSE139248: Genetic heterogeneity profiling by single cell RNA-sequencing
We delineate subclonal expansion in a mouse melanoma models in response to immunotherapy, highlighti...
GSE144997: Determining ribosome-associated mRNA in motor neurons in adult GarsC201R/+ mice [16NGS-002-burgess]
To determine transcriptome changes in motor neurons induced by the GarsC201R mutation.; How mutation...
GSE139987: Altered expression of long non-coding and messenger RNAs in diabetic nephropathy following treatment with rosiglitazone
Diabetic nephropathy (DN) is characterized by metabolic disorder and inflammation. However, the regu...
GSE132079: RNA-seq analysis of transcriptomic changes in bone marrow LSK cells in WT, G12D, Ezh2-KO and G12D with Ezh2-KO (G12D_Ezh2-KO) mice [RNA-seq]
Epigenetic gene regulation and metabolism are highly intertwined, yet little is known whether and ho...
GSE145012: Transcriptional profiling of germ-free and conventionalized mouse liver
The microbiome has been shown to have significant effects on susceptibility to liver disease. How th...
GSE148102: Transcriptomic profiling of isolated mouse Merkel cells [SMARTseq]
Merkel cell carcinoma (MCC) is a highly aggressive, neuroendocrine skin cancer that lacks actionable...
GSE133019: Whole genome transcriptome of in vivo Treg cells and ex vivo TGF-beta induced Treg cells from WT and Aim2 knockout mice
To understand the whole genome transcriptome of in vivo Treg cells and ex vivo TGF-beta induced Treg...
GSE149132: Translational control of breast cancer plasticity
Plasticity of neoplasia, whereby cancer cells attain stem-cell-like properties, is required for dise...
GSE141312: Differential Regulation of Alcohol Consumption and Reward by the Transcription Cofactor LMO4
The goal of this study is to identify and validate transcriptional targets of LMO4 in the Basolatera...
GSE147911: Genome-wide transcriptome analysis of the STAT6-regulated genes in advanced-stage cutaneous T-cell lymphoma [Bulk-seq]
The signal transducer and activator of transcription 6 (STAT-6) is a critical up-stream mediator of ...
GSE141057: CLIC4 is essential for host competence for metastasis in murine models of breast cancer and a prognostic indicator for human breast cancer
CLIC4 belongs to a family of highly conserved metamorphic proteins of the glutathioneStransferase su...
GSE132508: TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease
CD33-/- and/or TREM2-/- mice were crossed with the 5xFAD mouse model of Alzheimers disease to genera...
GSE149154: LCM-RNAseq on human pyramidal neurons and parvalbumin interneurons from frontal cortex
Pyramidal neurons and aggregcan-positive interneurons were collected from healthy control human post...
GSE147910: Human immature neutrophils as a functional biomarker of systemic vascular pathologies
We used an ex vivo system of murine ER-Hoxb8 neutrophils that phenotypically and morphologically rec...
GSE148130: Transcriptome analysis of synovial osteoprogenitor populations in mice with antigen-induced arthritis and non-immunized mice
The aim of this experiment was to analyze differences in gene expression between potential osteoprog...
GSE132728: RNA-sequencing of paired normal-adjacent and liver tumor tissue from WT and Liver MPC-knockout mice
Purpose: Liver-specific MPC-knockout (Mpc1-/-, LivKO) mice develop less liver tumors than wild-type ...
GSE146247: SIRT7 counteracts mesenchymal stem cell senescence via stabilizing heterochromatin
Human mesenchymal stem cell (hMSC) senescence contributes to the imbalance of tissue homeostasis dur...
GSE133927: RNA-Sequencing analysis of Meox1 siRNA knockdown in p53 and PTEN deficient triple negative breast cancer in vitro cell lines of BT-549 and MDA-MB-468
The goal for this experiment was to analyze how knockdown of homeobox transcription factor Meox1 alt...
GSE143944: Transcriptional profiling of ribociclib-treated sensitive and ribociclib resistant CAMA-1 cells
We report transcriptional response to ribociclib treatment in resistant and sensitive CAMA-1 cells u...
GSE148629: Transcriptional profiling of the prefontal cortex and nucleus accumbens of mice upon chronic stress
The goal of this study is to characterize the transcriptional responses of mitochondria associated g...
GSE136789: Oligomeric human A1-42 inhibits antigen presentation
The goal of this study is to investigate the involvement of inflammation in Alzheimers disease (AD) ...
GSE145609: Defining totipotency using criteria of increasing stringency
Totipotency is the ability of a single cell to give rise to all the differentiated cells that build ...
GSE142633: Next-generation sequencing of wild type and 5XFAD transcriptomes for Alzheimer's disease study
We found some novel miRNA that targets SIRT1 may contribute to the pathogenesis in AD mouse model. W...
GSE131315: The DEL-13 integrin axis promotes Runx-1dependent Foxp3 expression and regulatory T cell responses at mucosal barrier sites
Foxp3+CD4+ regulatory T cells (Tregs) are critical for immune homeostasis and respond to local tissu...
GSE143941: Classification of Primary Liver Cancer with Immunosuppression Mechanisms and Correlation with Genomic Alterations
Background: The tumor microenvironment can be classified into immunologically active inflamed tumors...
GSE148937: Targeted next generation sequencing of transcriptomes from human treatment-nave patient-derived prostate tissues, organoids, and organoid-derived cells (unaffected and tumor counterparts)
Human prostate mRNA profiles of organoids, cells, and tissues were generated by targeted next genera...
GSE132438: Fc receptor-like 6 (FCRL6) defines pre-BCR dependent and independent pathways of natural antibody selection
B-1a cells produce natural antibodies (Abs) to neutralize pathogens and clear neo self-antigens, but...
GSE148910: Transcriptome analysis of CHAF1B depletion in Akata EBV+ Burkitt Lymphoma cells
RNAseq was used to identify host and EBV viral transcriptome changes in CHAF1B knock-out Akata EBV+ ...
GSE148974: An Integrated Epigenomic and Transcriptomic Map of Mouse and Human ab T Cell Development (RNAseq Exp2)
ab lineage T cells, most of which are CD4+ or CD8+ and recognize MHC I or MHC II-presented antigens,...
GSE143953: RNA sequence of preeclampsia and healthy control placentas
Preeclampsia (PE) is a multi-system disorder that is primarily characterised by new-onset hypertensi...
GSE145710: Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy (human)
Intellectual disability (ID) is a heterogeneous clinical entity and includes an excess of males who ...
GSE149137: HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases
HACE1 is an E3 ubiquitin ligase with important roles in tumor biology and tissue homeostasis. Loss o...
GSE141419: Transcriptomic analysis of nave B cells and antigen-specific activated B cells and plasma cells from 4dpi NP-LPS immunized mice [Blimp1_reporter_PC_stim]
Though it is known that plasma cells utilize the unfolded protein response to remodel their ER it is...
GSE131420: Analysis of transcriptomic profile of iNKT cells
The maintenance of tissue homeostasis is critically dependent on the function of tissue-resident lym...
GSE131300: JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors
Tumor-associated macrophages contribute to tumor progression and therapeutic resistance in breast ca...
GSE143934: The response to the growth inhibitory activity of bone morphogenetic protein 4 in human glioblastoma cell lines is heterogeneous and dependent on SOX2
Glioblastoma multiforme (GBM) continues to have a dismal prognosis. Even though detailed information...
GSE144559: Total RNA Sequencing of control and huntington's disease iPSC-derived medium spiny neuron-like cells
HD and control patient-derived induced pluripotent stem cells were used to generate medium spiny neu...
GSE140513: Vascular PPARb/d Promotes Tumor Angiogenesis and Progression
PPAR/ has been suggested to be involved in the regulation of the angiogenic switch in tumor progress...
GSE134706: Cross-species analysis across 450 million years of evolution reveals conservation and divergence of the microglia program (bulk RNA-seq)
Here we characterize microglia transcriptional program across ten species spanning more than 450 mil...
GSE148991: Unlocking the keys to metastasis: A novel culture method for efficient propagation of Circulating Tumor Cells
Circulating Tumor Cells (CTCs) from metastatic breast cancer patients were harvested and grown in vi...
GSE141444: High-dose Ascorbic acid synergizes with anti-PD1 in a Lymphoma mouse model
Major efforts are underway to identify agents that can potentiate effects of immune checkpoint inhib...
GSE144588: RNA-seq mouse donor T-cells after day of BMT
RNAs isolated from mouse T cells were processed for sequencing. Naive T cells were wer isoalted from...
GSE145774: Multi-omics HUVEC data of Tibetan and Han in hypoxic induction.
Tibetan's adaptation to high-altitude environment at the Qinghai-Tibetan plateau represents a remark...
GSE131404: IRE1-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain
The IRE1-XBP1 arm of the unfolded protein response (UPR) maintains endoplasmic reticulum (ER) homeos...
GSE149084: Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomics in children with Cryptorchidism
Cryptorchidism is the most common congenital defect in children's genitourinary system. It is one of...
GSE141186: H1 linker histones regulate the balance of repressive and active chromatin domains via localized genomic compaction [RNA-seq]
H1 linker histones are the most abundant chromatin binding proteins. Their association with chromati...
GSE141912: Transcriptomic profiling of murine Nfe2l2 knockout melanoma cells
The role of Nfe2l2 in established murine melanoma cells was studied by analyzing expression profiles...
GSE139932: Profiling of RNAs from human islet-derived exosomes in a model of type 1 diabetes
Type 1 diabetes (T1D) is characterized by immune mediated destruction of insulin producing cells. B...
GSE152250 (human): Metabolic dysfunction is integral to TGFb signaling and tissue fibrosis
Fibrosis, or the accumulation of extracellular matrix, causes loss of organ function and is a common...
GSE143929: Gene expression profile of primary cultures of neonatal cardiomyocytes treated with specific GapmeRs
The eRNAs are non coding transcripts involved in the control of gene expression. To verify the biolo...
GSE131366: Distinct Contribution of DNA Methylation and Histone Acetylation to the Genomic Occupancy of Transcription Factors
DNA methylation has been shown to act by directly modulating transcription factor affinity to DNA bi...
GSE141322: Bisphenol A and Bisphenol S Disruptions of the Mouse Placenta and Potential Effects on the Placenta-Brain Axis
C57BL6J mice were fed 200ug/kg body weight BPA or BPS for two weeks and then bred. Placenta tissue w...