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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Long non-coding RNAs (lncRNAs) are important regulators of biological processes including immune res...
MeCP2 (methyl CpG binding protein 2) is a key component of constitutive heterochromatin, which plays...
Allogenic hematopoietic stem cell (HSC) transplantation is widely used for treatment of blood disord...
The formation, maintenance, and repair of the blood-brain barrier (BBB) are critical for central ner...
Purpose of this study is to identify the role of DJ-1 in the brain inflammation at moleculer level. ...
We have obtained RNAseq data from the livers of male C57BL/6J and BALB/c that were maintained on a l...
Purpose: Chromatin architecture is an important regulator of gene expression, but details of how DNA...
Dendritic cells (DC) are antigen presenting cells controlling T cell activation. In human, the diver...
This study investigated the effects of IL1RL1 deficiency on the devlopment of red pulp macrophages (...
We constructed a searchable genome-wide atlas of mRNA abundance, splicing and editing alterations du...
Among primates, humans display a unique trajectory of development responsible for the many traits sp...
Intrauterine infusion of CXCL12 has a beneficial effect on endometrial angiogenesis by recontruction...
Population based transcriptomic profiling was performed on microglia isolated from TNF or GMCSF trea...
Somatic cell nuclear transfer (SCNT) can reprogram a somatic nucleus to a totipotent state. However,...
The goal of this study was to compare Next Generation mRNA Sequencing (RNA-seq) data obtained from a...
Genetic alterations in members of the nucleotide excision repair (NER) pathway are present in a wide...
The aim of this study was to investigate the stability of DNA methylation, the dynamics of different...
CCCTC binding factor (CTCF) is an important factor in the maintenance of chromatin chromatin interac...
The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. De...
To determine transcriptome changes in spinal cord induced by the GarsdelETAQ mutation.; How mutation...
We evaluate heterozygous transgenic mice expressing human ACE2 receptor driven by the epithelial cel...
Classical dendritic cells (cDCs) are rare sentinel cells specialized in the regulation of adaptive i...
To determine transcriptome changes in motor neurons induced by the GarsP278KY mutation.; How mutatio...
Coronavirus EndoU inhibits double-stranded RNA (dsRNA)-activated antiviral responses; however, it is...
Increasing energy expenditure through activation of brown adipose tissue (BAT) thermogenesis is an a...
This study used nasal transcriptomic profiling of the inferior turbinate in control and pediatric AR...
Air pollution particulate matter <2.5 microns (PM2.5) is associated with poor respiratory outcomes. ...
To determine combination effect of GSK126 and pomalidomide at the RNA levels in EZH2 Y641 mutant DLB...
mRNA, lncRNA, and miRNA signatures were identified to discriminate cervical adenocarcinoma from norm...
We perform expression analysis on a panel of four T-cell lymphoma lines exposed to romidepsin and 5-...
RNA-seq was performed to interogate the transcriptional changes in response to infection with Adhere...
3D cell cultures are becoming more and more important in the field of regenerative medicine due to t...
First line treatment with AKT inhibitors combined with paclitaxel improves outcomes of metastatic TN...
To investigate the molecular mechanisms that lead to CL/P in Esrp1-/- mice, we performed RNA-Seq usi...
No disease-modifying drugs exist to treat osteoarthritis (OA), a degenerative disease of the joint. ...
Paneth cells are important for maintaining epithelial cell renewal and modulating innate immune func...
piRNAs are a novel class of small noncoding RNAs that were recently identified in animal germ cells....
Virus species- and tissue-tropism is governed by host dependency and restriction factors. Hepatitis ...
WEE1 is a cell cycle and DNA damage response kinase that is emerging as a therapeutic target for can...
These studies identify a novel node of AR-regulated DNA repair through CRY1 directly regulating HR-m...
Investigation of the physiogical functions of YAP/TAZ in vascular smooth muscle cells SOURCE: Stefan...
To investigate insight into how Esrrg regulates the TREG transcriptional program, we performed high-...
The UPF3B-dependent branch of the nonsense-mediated RNA decay (NMD) pathway is critical for human co...
Our previous study demonstrated that Galectin-1 plays a protective role for colitis by binding with ...
We evaluated the potential importance of adipose tissue (AT) oxygenation on AT biology and insulin s...
We detected the contributions of CpG methylation in gene promoter to the expression of acute phase p...
This experiment was conducted to identify mRNA transcripts alteration in skeletal muscle of MLL4SET ...
PAK4 was knocked down in human glioblastoma (GBM)-associated endothelial cells (ECs) using CRISPR-Ca...
We provide a comprehensive assessment of the cellular, immunological, physiological and transcriptom...
The differentiation and homeostasis of Foxp3+ regulatory T (Treg) cells is strictly controlled by T ...
Stress granules (SG) are membrane-less ribonucleoprotein condensates that form in response to variou...
The paucity of genetically informed, immune-competent tumor models impedes evaluation of conventiona...
Treml4 has been recently caracterized as a protein-coding gene of the Trem family. It has been shown...
Purpose: The cranial suture is a fibrous joint, and similar to the growth plates of the skeletal lon...
Chronic obstructive pulmonary disease (COPD) is a highly prevalent respiratory disease characterized...
We reported transcriptional characterization of vTreg53 TCR transgenic Treg cells from splenic/lymph...
Microdeletions and microduplications of the 16p11.2 chromosomal locus are implicated in a collection...
Analysis of colorectal primary tumors (pTU) and liver metastases (LM) tissue samples from patients a...
Current management of childhood leukemia is tailored based on disease risk determined by clinical fe...
We report the transcriptional changes with knock down of HDAC1 and HDAC2 from the epithelium of the ...
We examined here the regulation of gene expression in ventral hippocampus neurons that project to nu...
Neurogenesis is limited in mammalian brains and Alzheimers disease conditions further reduce the neu...
Background: Single-cell RNA sequencing has been widely adopted to estimate the cellular composition ...
Cultured dorsal root ganglia neurons of 4 and 12 weeks old C57Bl/6 mice were first characterized as ...
Phenotypic plasticity and partial EMT underlie local invasion and distant metastasis in colon cancer...
EGFR tyrosine kinase inhibitors (EGFR TKIs) are the standard of care treatment for patients with EGF...
The uptake of macromolecules and cellular debris through macropinocytosis has emerged as an importan...
Ischemic stroke is one of the leading causes of mortality and major healthcare and economic burden. ...
The purpose of this study was to elucidate the transcriptome of ER expressing MDA-MB-231 cells follo...
Mesenteric lymph node (mLN) T cells undergo tissue adaptation upon migrating to intestinal lamina pr...
Oxidative stress is a central part of innate-immune induced neurodegeneration. However, the transcri...
ALKBH5 is the RNA N(6)-methyladenosine (m6A) demethylase. To understhand the function and mechnism o...
Retinoic acid (RA) signaling is essential for multiple developmental processes, including appropriat...
Mice maintained on high-fat diet (Research Diets #D12492) for 37 weeks. SOURCE: Alexander Banks (asb...
Zygotic genome activation (ZGA) is a crucial developmental milestone that remains poorly understood....
Prostate cancers (PC) with loss of the potent tumor suppressors TP53 and RB1 exhibit poor outcomes t...
With advances in single-cell genomics, molecular signatures of cells comprising the brain vasculatur...
Here we investigated the underlying mechanisms causing the suppression of normal immune responses wh...
We performed RNAseq to study the transcriptional changes of human CAOV2 ovarian cancer cells with or...
To test the effect of fatostatin on gene expression patterns in microglia, we treated mouse (C57BL/6...
A disturbance of histone protein composition renders nuclear DNA immunogenic, inducing a type I inte...
We report the generation of a novel mouse strain that is immunologically tolerant to exogenously int...
Maternal infection and inflammation during pregnancy is associated with neurodevelopmental disorders...
TBK1 is a multifunctional kinase phosphorylating a variety of proteins triggering innate immune sign...
Microglia are the tissue macrophages of the central nervous system (CNS) and the first to respond to...
Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (...
The ability of B-1 cells to become positively selected into the mature B cell pool, despite being w...
Glioblastoma is the deadliest adult brain cancer and all patients ultimately succumb to the disease....
Ribosome footprint profiling is a high throughput sequencing based technique that provides detailed ...
Osteoarthritis (OA) is a highly prevalent and morbid disease affecting over 30 million Americans. Ef...
The ability of Toxoplasma gondii to inject the rhoptry kinase ROP16 into host cells results in the a...
Tumor-associated microglia and macrophages (TAM) are the most numerous non-neoplastic populations in...
The differentiation of patient-specific induced pluripotent stem cells (iPSCs) into specific neurona...
In this experiment we compare the expression profile of genes present in the lymph node or spleens o...
To understand the mechanism of lncRNA-DRR induced effect on cardiomyocyte proliferation, high-throug...
Our study prompeted us to assign, through spiked single cell RNAseq, metastatic function to transcr...
We report differential effects of mutations in genes of the homologous recombination (HR) pathway on...
Among the non-polio enterovirus (NPEV) Echovirus-30 (E-30) is responsible for extensive global outbr...
ssRNA-seq analysis of the transcriptional landscape of 38 multiple myeloma patients SOURCE: Xabier A...
Purpose: The presence of a phagocytic peak of photoreceptor outer segments by the retinal pigment ep...