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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
NOTCH1 gain-of-function mutations are recurrent in B cell chronic lymphocytic leukemia (B-CLL), wher...
The goals of this study are to analyze the DEGs of the spinal cord cells in scramble microPEP(Scr) o...
The present study aims to investigation alterations in the transcriptional profile when cells acquir...
Overnutrition leads to metabolic disorders such as obesity and diabetes. Enhanced inflammation has a...
RNA-seq of sorted Pou5f1:EGFP-positive spermatogonia from adult testes. SOURCE: Maria,M,MikedisPage ...
Comparison of differential expression between macrodactyly BMSC and polydactyly BMSC SOURCE: Hengqin...
We used NGS-derived transcriptome profiling (RNA-seq) to compare the transcriptional difference betw...
The goal of this experiment was to determine differential gene regulation of PGC1 or ERR compared to...
Cutaneous squamous cell carcinomas (cSCC) are frequent heterogeneous tumours, arising from sun-expos...
Lynch syndrome (LS) patients are at markedly increased risk for colorectal cancer. It is being incre...
We used RNA sequencing to analyze the genomic signatures of prostate cancer that progressed after ta...
The ketogenic diet has been successful in promoting weight loss among patients that have struggled w...
The goal of this experiment was to find global transcriptional changes upon BRD4 deletion. We report...
Advanced cell culture methods to model organ function have been demonstrated to better replicate in ...
The study aimed to investigate molecular signatures in peripheral blood of individuals affected by m...
Transmembrane proteins are important for intercellular signaling and play important roles in the con...
Hnrnpu is the largest member of the heterogenous nuclear ribonucleoprotein family of RNA binding pro...
These are RNA sequencing data from embryonic day 18 whole brains from embryos whose mother's were ex...
We performed paired-end poly A+ RNA sequencing using total RNA isolated from serum starved and seru...
In this study, we established that PAF1 is critical for pancreatic tumorigenesis, and CSC-driven tum...
Surfactant protein A (SP-A) in addition to its surfactant-related functions interacts with alveolar ...
Analysis of primary fibroblasts isolated from human colorectal primary tumors(CAFs) and liver metast...
The aim of this study was to test the role of ROR in the action of the above analogs using murine fi...
Idiopathic pulmonary fibrosis (IPF) is a type of pulmonary fibrosis, a disease that results in scarr...
Injury induces retinal Muller glia of non-mammalian, but not mammalian, vertebrates to generate neur...
We demonstrated that natural killer (NK) cells selectively suppress single circulating tumor cells (...
Protein Arginine Methyltransferase (PRMT) 5 catalyzes symmetric dimethylation of arginine, a post-tr...
We used novel genetically engineered mouse models to investigate the role of HELLS during tumorigene...
The discovery of H3K27M mutations in pediatric gliomas marked a new chapter in cancer epigenetics. N...
Here, we identified METTL6 as abona fidetRNA methyltransferase, catalysing the formation of 3-methyl...
Intravasation, vascular dissemination and metastasis of malignant tumor cells require their passage ...
The transcriptome sequencing results were used to determine the association between UBE2C and pancre...
Classical dendritic cells (cDCs) are rare sentinel cells specialized in the regulation of adaptive i...
Despite the growing recognition of the role of the stroma in cancer growth, invasive behavior and me...
The tumor microenvironment plays a critical regulatory role in cancer progression, especially in met...
To confirm the neuroblastomas (NB) identity of human neuroblastomas from mouse-human neural crest c...
Treml4 has been recently characterized as a protein-coding gene of the Trem family. It has been show...
Background: We previously reported on the role of pericyte-like cells as functional sentinel immune ...
Insight on molecular and cellular responses to sleep loss provides a clearer understanding of sleep ...
Background: Recent transcriptomic studies of total glomerular and isolated glomerular endothelial ce...
In this study, we compared the transcriptional profile of NIH-3T3 cells that are either wild-type (W...
We profile gene expression upon circCDYL KD in HepG2 cells and in two bladder cancer cell lines J82 ...
RNA-seq comparing WT and caERBB2 over expresising hearts with/out injury SOURCE: Eldad Tzahor Weizma...
We identified IGF2BP1 as a marker of the C5 molecular subtype of high-grade ovarian carcinoma (HG-SO...
The expression of the extracellular sulfatase, SULF2, has been strongly associated with increased he...
Purpose: Immunoglobulin A nephropathy (IgAN) is immune-mediated primary glomerulonephritis, which is...
Recent studies suggested that crosstalk between ER and EGFR/HER2 pathways plays a critical role in m...
We report the high-throughput profiling of murine intestinal type 2 innate lymphoid cells (ILC2) tra...
MCF10A cells were CRISPR-Cas9 edited to create heterozygous deletion in RAD21 and SMC3 subunits of c...
Accurate analysis of gene expression in human tissues using RNA Sequencing is often dependent on the...
N6-methylation of 2-O-methyladenosine (Am) in RNA occurs in eukaryotic cells to generate N6,2-O-dime...
We report the transcriptomic profile of uterine tissues obtained from the control (Wnk1f/f) and Wnk1...
Methylmercury (MeHg) is a well-known neurotoxicant, particularly harmful for the developing brain. S...
Forkhead box a2 (FOXA2) is a transcription factor expressed specifically in the glands of the uterus...
Bile acids act as ligands for several nuclear receptors expressed in the small intestine, especially...
Hypoxanthine phosphoribosyl transferase 1 (HPRT1) is traditionally believed to be a housekeeping gen...
Here, we studied the interaction between dietary (TWD) and genetic factors (APPswe/PS1dE9 and tau P3...
Ovarian cancer (OC) is the leading cause of death from gynecologic malignancies in the US. Ovarian c...
CBP/p300-interacting transactivator with glutamic acid/aspartic acid-rich carboxyl-terminal domain 2...
Cancer vaccines utilizing naturally circulating dendritic cell (DC) subsets, such as plasmacutoid DC...
Regulatory T cells (Tregs) are enriched in the tumor microenvironment (TME) and suppress anti-tumor ...
Lynch syndrome (LS) patients are at markedly increased risk for colorectal cancer. It is being incre...
The heterochromatin protein 1 (HP1) family members are canonical effectors and propagators of gene r...
We investigated genome wide changes in gene expression in skin between patients with type 2 diabetes...
Murine RPE transcriptomes were generated for 6 time points during a 24 hour period. Our data demonst...
The relative contribution of genetic and environmental factors to variation in immune response is st...
Zygotic genome activation (ZGA) is the first transcription event in life. However, it is unclear how...
Functional analysis of transcriptome (mRNA and microRNA) and proteome formation during treatment of ...
Promising activity of BET protein inhibitors (BETis) is compromised by adaptive or innate resistance...
These experiments were part of a larger study investigating abnormal bowel motility in mice lacking ...
Here, we implemented a computational pipeline to determine the correlation of expression between ind...
The DNA-binding protein CTCF and the cohesin complex function together to shape chromatin architectu...
As part of characterizing the novel pogz deficiency mouse model, we performed RNA-Seq from cerebellu...
Under steady state conditions, the immune system is poised to sense and respond to the microbiota. A...
To explore this question, we will use three different male mouse models including VDR KO mice and tr...
Gene expression was evaluated by RNA-seq of mouse pancreas 5 days following chronic caerulein-induce...
We profiled RNA expression in human iPSC-derived cardiomyocytes from patients with LZTR1-associated ...
We performed single-cell RNA-seq (10x Chromium 3' v.2) on dissociated single cell suspensions from m...
CTCF is a key insulator-binding protein and mammalian genomes contain numerous CTCF-binding sites (C...
To gain a deeper insight into roles of Arid1a in injured retinal ganglion cells (RGCs), we performed...
We aim at identifying genes enriched in POMC neurons versus NPY neurons that were involved in glutam...
Purpose: To understand compound effects on human macrophage repolarization in the transcriptional le...
Alopecia areata (AA) is one of the most common autoimmune conditions, presenting initially with loss...
Development of effective therapies against brain metastasis is currently hindered by limitations in ...
Specialized pro-resolving mediators (SPMs) function to limit inflammation and actively stimulate SOU...
Mesp1-Cre+ cells from E7.5 mouse embryos (from the cross Mesp1-Cre/+ x Rosa26-Gli3R-IRES-YFP/tdTo...
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian hippocampus. However,...
RNA-seq analysis of sorted WT and Klf5/Smad4/Egfr-KO 6694c2 mouse pancreatic tumor cells from subcut...
AbstractDNA transfection is widely used in biomedical research. However, transfection efficiency is ...
We report the effects of Hfol on TNF induction of inflammatory genes in wild type cells versus cells...
Long non-coding RNAs (lncRNAs) are important regulators of biological processes including immune res...
We analyzed wildtype and miR-302 knockout embryos at E7.5 and sorted neural crest using Wnt1-Cre at ...
To shed light on the complexity of tumor-infiltrating immune cells in non-small cell lung cancer (NS...
Merkel cell carcinoma (MCC) is a highly aggressive, neuroendocrine skin cancer that lacks actionable...
The cellular stress response triggers a cascade of events leading to transcriptional reprogramming a...
To identify KLF5 target genes and study the gene regulation function of KLF5 by integrating ChIP-seq...
To evaluate the effects of ALKBH5 KD on the mRNA stability, we conducted RNA-seq of mRNA samples enr...
Purpose: To build a differential transcriptome network in Smug1 knock-out HepG2 hepatocarcinoma cell...
Tuberculosis (TB) remains the worlds top infectious killer. Understanding how immune mediators deter...
The interaction of Menin (MEN1) and MLL (MLL1, KMT2A) is a dependency and potential therapeutic oppo...