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Sequencing-based assays (Page 11)
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GSE86927: Impact of NCoR1 on global transcriptomic profiling in intestinal epithelial cells during development
To explore the molecular events engaged following the deletion of NCoR1 in intestinal tissue during ...
GSE84942: Global Deletion of TSPO Does Not Affect the Viability and Gene Expression Profile.
Translocator Protein (18kDa, TSPO) is a mitochondria outer membrane transmembrane protein and which ...
GSE85423: RNA sequencing of mice fed a high fat/high sucrose diet or a low fat/low sucrose diet
Publication Title: DNA methylation alters transcriptional rates of differentially expressed genes an...
GSE84186: Single-nucleotide-resolution mapping of HBV promoters using CAGE
We provide a comprehensive map of transcription start sites (TSSs) for HBV at single nucleotide reso...
GSE89272: Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions (RNA-Seq)
Investigation into changes in the methylome in young (2 months) and aged (22 months) Ames dwarf (Pro...
GSE84953: Cnot3-dependent mRNA deadenylation safeguards the pluripotent state
Poly(A)-tail length and mRNA deadenylation play important roles in post-transcriptional gene regulat...
GSE83541: Zinc finger protein overexpression improves glucose homeostasis in mice
Using RNA-Seq, we compared the transcriptomes of muscle from wild type C57BL/6J or Zp407 transgenic ...
GSE97658: Quantitative Analysis of JAK2V617F/+ Plek2+/+ and JAK2V617F/+ Plek2-/- erythroblast and hematopoietic stem cells/ progenitor cells Transcriptomes
V617F driver mutation of JAK2 is the leading cause of the Philadelphia-chromosome-negative myeloprol...
GSE89044: Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq
The kidney differentiation protocol takes induced pluripotent stem cells through to kidney organoid ...
GSE89030: Analysis of gene expression profiles from alloreactive TCR-Tg CD8 T cells during activation and induction of tolerance
RNA-seq was used to evaluate transcriptional changes in alloreactive TCR-Tg CD8 T cells during activ...
GSE136232: Regulatory interaction between the ZPBP2-ORMDL3/Zpbp2-Ormdl3 region and the circadian clock (RNA-seq at ZT7)
Purpose: Identifying the biological pathways affected by the deletion of the zona pellucida binding ...
GSE83145: RNA profiling of testis from wild-type and tamoxifen-induced NIPP1 knockout mice
This study aimed to explore the role of NIPP1 in adult germline cell proliferation and differentiati...
GSE90659: Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq]
RNA-seq was performed in human Ph+ pre-B ALL cells that harbor a deletion of the Ikaros DNA binding ...
GSE77647: RNA-binding proteins Cugbp1 and HuD regulate neocortical projection neuron identities under the translational control of Neurotrophin-3
Intrinsic molecular pathways in the central nervous system dictate neuronal cell fate during develop...
GSE93263: Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq]
MyoD is known to transdifferentiate fibroblasts into muscle-like cells. Despite phenotypic resemblan...
GSE81670: Comparison of Kras;Rank+/+ and Kras;Rankfl/fl mouse primary pneumocytes treated with Rankl ex vivo
The transcriptional profile of Kras;Rank +/+ and Kras;Rank fl/fl mouse primary pneumocytes were dete...
GSE114011: E-cadherin suppresses invasion and promotes metastasis in multiple breast cancer models
E-cadherin (E-cad) mediates cell-cell adhesion and has been proposed to suppress both invasion and m...
GSE84988: Expression of MLL-ENL in hematopoietic stem cells induces mixed lineage acute leukemia
The t(11;19)(q23;p13.3) translocation leading to the expression of an MLL-ENL fusion is one of the m...
GSE114018: HNF4 Pathway Mapping Identifies Wild-type IDH1 as a Targetable Metabolic Node in Gastric Cancer
Comprehensive downstream mapping of HNF4 revealed its role in regulating GC metabolism via regulatio...
GSE84994: RNA-seq analysis of livers of mice fed a high fat diet with and without administration of an inhibitor of the ileal bile acid uptake transporter ASBT
The study was designed to determine the effect of inhibition of ileal bile acid uptake on hepatic ge...
GSE149870: A paired gRNA/Cas9 exon excision screen reveals the essentiality of ultraconserved poison exons
Paired gRNA/Cas9 delivery facilitates the removal of alternative exons and reveals splicing dependen...
GSE77778: Protracted NP95 binding to hemimethylated DNA disrupts SETDB1-mediated proviral silencing [RNA-seq]
Genetic ablation of the maintenance methyltransferase Dnmt1 induces widespread demethylation and tra...
GSE78691: Combination targeted therapy to disrupt aberrant oncogenic signaling and reverse epigenetic dysfunction in IDH2- and TET2-mutant acute myeloid leukemia (RNA-Seq)
Genomic studies in acute myeloid leukemias (AML) have identified mutations which drive altered DNA m...
GSE94436: Gene profiles in inguinal white adipose tissue in Hsp20 knockout mice
To investigate the function of HSP20 in adipogenesis and thermogenesis of white adipose tissue. SOUR...
GSE84705: Stochastic capture of chromatin topological domains by nuclear matrix RNA polymerase II determines monogenic choice
Antigen receptor gene recombination requires stochastic, monoallelic choice of a single variable gen...
GSE90697: Organism-level analysis of vaccination reveals networks of protection across tissues
To study the response of single lung and liver memory CD8+ T cells to reactivation, mice vaccinated ...
GSE109231: RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses
Precursor T-cell lymphoblastic neoplasms are aggressive haematological neoplasm that most often mani...
GSE90711: Proteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype
The remarkable feature of Schwann cells (SCs) to transform into a repair phenotype turned the spotli...
GSE85731: Epigenetic memory of obesity in mouse colonic epithelium
Colorectal cancer is the third most common cancer. Obesity is a major risk factor with long-lasting ...
GSE86976: Protein Kinase CK2 Controls the Fate Between Th17 Cell and Regulatory T Cell Differentiation
We report that CK2 inhibition with CX-4945 broadly suppresses Th17-associated effector and metabolic...
GSE95078: Transcriptional responses to TNF-alpha in germline A20 haploinsufficiency
Early-onset complex autoimmunity can arise from monogenic activating mutations in inflammatory signa...
GSE94430: Capturing the onset of PRC2-mediated repressive domain formation (RNA-Seq)
Our study defines nucleation and spreading regions for Polycomb repressive complex 2 (PRC2), demonst...
GSE86956: Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq]
To identify genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells, we analyzed the whole-tr...
GSE80036: Targeted deletion of an Nr4a1 associated enhancer ablates Ly6Clow monocytes while protecting pleiotropic gene function in macrophages [RNA-seq]
Mononuclear phagocytes are a diverse cell family that occupy all tissues and assume numerous functio...
GSE84661: Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq]
Genome-wide chromosome conformation capture (Hi-C) and promoter-capture Hi-C (CHi-C) were performed ...
GSE85671: The Genomic Landscape of Atypical Fibroxanthoma
In this study, we used exome sequencing and RNA sequencing to describe the genomic landscape of Atyp...
GSE84292: Identification of transcriptomic drivers of squamous cell carcinoma development through a preneoplastic intermediate [mouse RNA-Seq]
Cutaneous squamous cell carcinoma (cuSCC) comprises 15-20% of all skin cancers, accounting for over ...
GSE86653: Time course of the miR-203 effect during reprogramming from somatic cells to pluripotent cells
The balance between pluripotency and differentiation is critical during development and regeneration...
GSE89725: The mRNA expression analysis of psoriasis skin lesion mesenchymal stem cell
RNA sequencing for 6 samples from psoriasis skin lesion mesenchymal stem cell, to examine the differ...
GSE97764: The microprotein Minion controls cell fusion and muscle formation
These findings establish minion as a novel microprotein required for muscle development, and define ...
GSE99180: CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures
CD133hi, Notchhi, DP and DN cells were FACS-isolated from GBML8 and GBML20 cultures and analyzed wit...
GSE90758: RNA-SEQ of mutants B cell for IgH 3'RR and Emu
RNA-SEQ of mutants B cell for IgH 3'RR and Emu SOURCE: Kevin LebrigandFunctional Genomics Platform o...
GSE85648: Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer [seq]
PAX8-PPARG fusion protein (PPFP) results from a t(2;3)(q13;p25) chromosomal translocation,is found i...
GSE112251: Tumor immune evasion arises through loss of TNF sensitivity [Ado]
Investigation of the transcriptional response of wild type or Ado knockout MC38 cells to TNF SOURCE:...
GSE78964: Foxa2 identifies a novel ventricular-specific cardiac progenitor population during gastrulation.
The recent identification of novel progenitor populations that contribute to the developing heart in...
GSE99296: -ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming
We conducted gene expression analysis of naive and polarized macrophages from wild type C57BL6/J mic...
GSE87050: RNA-Sequencing analysis of BET inhibitor resistant cell lines
Targeting BET bromodomain proteins utilizing small molecules in an emerging anti-cancer strategy wit...
GSE79951: Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms
Topoisomerase 1 (TOP1) inhibitors, including camptothecin and topotecan, covalently trap TOP1 on DNA...
GSE87186: Safety and Immunogenicity of the Recombinant BCG Vaccine AERAS-422 in Healthy BCG-nave Adults: A Randomized, Active-controlled, First-in-human Phase 1 Trial
We report a first-in-human trial evaluating safety and immunogenicity of a recombinant BCG, AERAS-42...
GSE86007: iPSC-Derived Cholangiocytes
Human iPS cells were differentiated to cholangiocyte-like cells thorugh five phases of endodermal di...
GSE85737: RNA-Seq Analysis of Gfi1b KO Hematopoietic Stem Cells
The zinc finger protein and SNAG domain transcription factor Gfi1b is highly expressed in hematopoie...
GSE94402: The gut microbiome drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
We investigate the microbial effects on DNA methylation and the transcriptome of intestinal epitheli...
GSE98082: RNA-sequencing from wild-type (WT) or Tie2-Ino80 knockout (KO) mouse embryo hearts
Purpose: Endothelial cell-specific knockout of the INO80 chromatin-remodeling complex in developing ...
GSE109074: Gene expression in adult sciatic nerves upon miRNA ablation and crush injury
We report RNA sequencing data from induced Schwann cell specific knockouts for DICER and DGCR8 as we...
GSE87068: RNA Sequencing Quantitative Analysis of RNA editing sites of Wild Type and ADAR1 editing deficient (ADAR1E861A) murine fetal RNA of various tissues
The Adar1 deaminase inactive mutant mouse tissue samples were obtain from the Walkley lab as describ...
GSE87615: ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq]
ASCL1 mediates neuronal differentiation of GBM stem cell (GSC) cultures upon Notch signalling inhibi...
GSE89736: Cdk8 overexpression effect in heart
Analysis of ventricular derived mRNA from cardiac specific Cdk8 overexpressing mice. Results provid...
GSE144622: Sex Diversity in Proximal Tubule and Endothelial Gene Expression in Mice with Ischemic Acute Kidney Injury
Female sex protects against development of acute kidney injury (AKI). While sex hormones may be invo...
GSE79238: Transcriptional Basis of Neuronal Diversity in the Mammalian Brain
Neuronal diversity is a defining feature of the mammalian brain deemed necessary for realizing the c...
GSE89742: Hippo Pathway Regulates Microarchitecture of Fibroblastic Reticular Cells in Lymph Node
To unveil the role of Hippo signaling in regulating the maintenance and integrity of FRCs in LNs. SO...
GSE85880: Genome-wide transcriptomicprofiling of cardiomyocyte differentiation from human ES cells and iPS cells under exposure to sublethal of isotretinoin (RNA-seq)
In this study, isotretinoin (INN)-induced alternations in transcriptome during caidiomyocyte differe...
GSE80708: An ES cellspecific NuRD complex functions through interaction with Wdr5
The Nucleosome Remodeling and Deacetylase (NuRD) complex is a chromatin regulatory complex that func...
GSE100217: Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder
This study examined if p53 was essential in the brains response to alcohol using a mouse model of fe...
GSE86083: Polycomb-mediated axial patterning requires nucleosome compaction [RNA-seq]
We determined by RNA-seq gene expression changes in mESCs following the induced expression of WT-, K...
GSE85532: RNASeq comparing Thpok and LRF-deficient Tregs to Control
The transcription factor Thpok is required for intrathymic CD4+ T cell differentiation and, together...
GSE87456: Hypoxic transcriptome of SQ20B human head and neck cancer cells
We have carried out deep directional sequencing of mRNA isolated from normoxic (control) SQ20B cell...
GSE85870: Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance
We report that some cancers have extensive loss of epigenetic and transcriptional fidelity, characte...
GSE129948: Bulk RNA-sequencing of spinocerebellar tract neuron populations in cervical and thoracic sections of mouse spinal cord
We profiled populations of mouse spinocerebellar tract neurons (SCTNs) in cervical and thoracic sect...
GSE87504: Expression analysis of wt and maternal Trim28 mutant E3.5 embryos
We performed RNAseq on 4 individual E3.5 control and maternal Trim28 blastocysts respectively in ord...
GSE85534 (mouse): Single Cell Transcriptome Conservation in Cryopreserved Cells and Tissues
Sample preservation method that maintains transcripts in viable single cells and so allows to discon...
GSE60873: Transcriptome of EBV-infected gastric cancer cell lines
To understand epigenic dysregulation of host and viral genes upon EBV infection in human gastric can...
GSE87088: The expression changes of RNA binding proteins during human myeloid differentiation
We used CD34-positive cells isolated from cord blood to differentiate to granulocytic and monocytic ...
GSE86199: Gene expression profiles of Hes1 positive retinal subsets
To analyze Mueller glia specific gene expression, Hes1-promoter-dEGFP mice was used. dEGFP positive ...
GSE83251: RNA-seq analysis of retinoic acid treated mouse neuromesodermal progenitors
Bipotent neuromesodermal progenitors (NMPs) residing in the caudal epiblast drive coordinated body a...
GSE85535: Catch-and-release of cytokines converts transient exposure into long-term inflammatory responses
We report that after cancer cells are exposed to a transient pulse (5h) of the pro-inflammatory cyto...
GSE84857: The Role of Epithelium EZH2 in Experimental Colitis
Despite recent progress, the contribution of epigenetic mechanisms to govern Inflammatory bowel dise...
GSE149359: Next generation sequencing facilities quantitative analysis of ASAP2 knockout or wild-type Panc1 and MiaPaCa2 cells
To assess potential gene expression changes by ASAP2 individual knockout in Panc1 and MiaPaCa2 cells...
GSE86794: Time course of the miR-203 effect on the transcriptomic profile of IPSCs
The balance between pluripotency and differentiation is critical during development and regeneration...
GSE85565: TCF21 and Aryl-hydrocarbon receptor gene cooperate to activate a pro-atherosclerotic gene expression program
Genome-wide association studies (GWAS) for coronary artery disease (CAD, also termed coronary heart ...
GSE85894: RNA sequencing of Mus musculus thymic lymphomas
RNA sequencing of Mus musculus thymic lymphomas SOURCE: Ludovic Deriano (ludovic.deriano@pasteur.fr)...
GSE89352: Phospholipase C pathway-dependent mTOR signaling controls IL-7-mediated early B cell development
We examined the global gene expression profile of PLC1/PLC2 double-deficient CLPsand B cell progenit...
GSE81724: A comprehensive analysis of gene expression patterns in wild-type and Batf2-/- bone marrow-derived macrophages (BMM)
We previously identified TLR-independent expression of 4933430F08Rik, encoding Batf2, in T. cruzi-in...
GSE84447: Unbiased genomic analysis of multiple stages of lung cancer development
To uncover the gene expression alterations that occur during lung cancer progression, we interrogate...
GSE81849: mRNA cap methylation in pluripotency and differentiation
The mRNA cap recruits factors essential for transcript processing and translation initiation.We repo...
GSE93902: Effect of BCL11B knockdown on transcriptome of human T-cell precursors
To investigate the role of BCL11B in the initial stages of human thymopoiesis, we performed loss of...
GSE142303: Bulk RNA seq of intestinal immune cells from nave, LCMV-Arm and LCMV-Cl13 infected mice
We report that the gastrointestinal tract (GIT) is a previously unappreciated long-term reservoir of...
GSE87144: RNA-Seq analysis of MRL-871 and control-treated C57BL/6 thymocytes and Rorc over-expressing cell lines
We report the genes that are differentially expressed in thymocytes upon treatment with MRL-871 in v...
GSE86165: GRO-seq from HCT116, MCF7 and SJSA cell lines treated with DMSO and Nutlin
To identify loci with transcriptionally engaged RNA polymerase, we performed GRO-seq analysis of col...
GSE142321: Genome wide RNA-sequencing of sorted human pluripotent stem-cell derived endothelial cells with CLDN5-GFP reporter (GFP+ and GFP-)
CLDN5-GFP reporter has been engineered in hPSCs. These cells have been differentiated to Ecs. Differ...
GSE84545: Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration [E16]
In order to understand if early epigenetic mechanisms instruct the long-term behaviour of neural ste...
GSE87544: Single-cell RNA-seq reveals hypothalamic cell diversity
We performed single-cell RNA-seq of mouse hypothalamus to reveal the cell diversity of this region. ...
GSE89764: Next Generation Sequencing of Pkd1 mutant kidneys
This study sough to understand the differential gene expression profile of Pkd1 mutant mice kidneys ...
GSE86236: Genetic vs Dietary Models of Iron Overload in the Mouse Liver
Iron overload causes the generation of reactive oxygen species, which can lead to lasting damage to ...
GSE129950: A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc
To elucidate whether lncRNA-AK096729 plays a role in colorectal cancer tumorigenesis, a RNA-seq an...
GSE85598: Three congruent human Schwann cell models of CMT1A reveal a converged phenotype
Three CMT1A patient Schwann cell populations which were derived from hESC, hiPSC, or direct converte...
GSE90522: Generation of virtual memory from relatively highly self-reactive is a mechanism of self-tolerance
Virtual memory T cell show an intermediate expression profile in between nave and true memory T cell...
GSE79352: The dynamic translatome of retinal ganglion cell axons during assembly and maintenance of the mouse visual system
Local mRNA translation mediates the adaptive responses of axons to extrinsic signals but direct evid...
GSE84458: TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells [RNA-seq]
TET enzymes oxidise DNA methylation as part of an active demethylation pathway. Despite extensive re...
GSE88709: Mouse neural stem cells heterozyous or null for Dgcr8
We isolated and characterized mouse neural stem cells that are heterozygous or null for Dgcr8 from E...
GSE85936: E2F3a mediates cocaine action in nucleus accumbens via alternative splicing and transcription
Long-lasting changes in neuronal gene expression in brain reward regions, including the nucleus accu...