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Sequencing-based assays page 12
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GSE87130: Transcriptional profiling of Regulatory T-cells isolated from neonatal skin and skin draining lymph nodes (SDLNs)
Purpose: The goals of this study were to identify preferential gene expression signatures that are u...
GSE85623: Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq]
Heterozygous mutations in GATA4 cause congenital heart defects and cardiomyopathy through unknown me...
GSE86337: Transcriptome profiling of 5 human adenocarcinoma cell lines
Purpose: The aim of this study is to compare the transcriptome profiles of a limited number of lung ...
GSE140852: RNA-seq of NIH3T3 cells treated with PBS or extracellular vesicles (EV) from MCF10A or MDA-MB-231 cells
To identify gene expression changes associated with treatment of EVs from MDA-MB-231 [231] and MCF10...
GSE85656: RNAseq analysis of lncRNA silenced primary melanoma cell line WM902B
Purpose: Study the changes in gene expression upon silencing of lncRNA TINCR; Methods: ...
GSE87189: The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment
RNA-seq from R-2HG sensitive leukemia cells treated with R-2HG or PBS. SOURCE: Jianjun Chen (jianche...
GSE98032: SiO2 Nanoparticles Modulate The Electrical Activity Of Neuroendocrine Cells Without Exerting Genomic Effects
Different electrophysiological approaches are combined with a genomic screening in order to analyze,...
GSE148410: RNA sequencing data of microglia isolated from brains of WT, Hexb-tdTomato, Hexb-CreERT2 and Hexb-KO mice. [Cre]
RNA sequencing of FACS sorted microglia isolated from brain tissue of WT, Hexb-tdTomato, Hexb-CreERT...
GSE99434: AP4 regulates stem and Paneth cell homeostasis and promotes adenoma initiation in the intestine (small intestinal organoid)
AP4 is frequently expressed in primary CRCs. However, the in vivo relevance of AP4 for development o...
GSE87200: Aurora B phosphorylates hnRNP U/SAF-A to facilitate XIST RNA removal from the inactive X chromosome during mitosis
We show that Aurora-B phosphorylates heterogeneous nuclear ribonucleoprotein U (hnRNP U) in the SAP ...
GSE122468: RNA-Seq of PreCFU-E and CFU-E progenitors from wild type and Scf mutants
It has been shown previously that endothelial cells and LepR+ stromal cells are the main sources of ...
GSE79408: Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity
Soybean oil consumption is increasing worldwide and parallels the obesity epidemic in the U.S. Rich ...
GSE90796: RNA-sequencing of human intestinal enteroids infected with or without human rotavirus (strain Ito)
We report the human intestinal epithelial host transcriptional response to human enteric virus infec...
GSE87198: RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells
We overexpressed ADAR1, ADAR2 and AIMP2 in HEK293 cells and examined editing using RNA-seq. SOURCE: ...
GSE90749: Induced Pluripotent Stem Cell Differentiation Provides an Approach for Functional Validation of GWAS Variants in Metabolic Disease
Genome-wide association studies (GWAS) have highlighted a large number of genetic variants with pote...
GSE87681: Analysis of gene expression from CD45neg cells of lung tumors upon neutrophil depletion or not
Interrogating the tumor immune compartment generates new prognostic and treatment modalities. We use...
GSE98198: MYOD Gene Expression Regulation during Myogenic Conversion of Fibroblasts
We provide here gene expression profile of IMR90 fibroblasts expressing or not MYOD culured in GM fo...
GSE87426: RNA-seq of human adipose tissue following n-3 PUFA supplementation and evoked endotoxemia
Dietary consumption of long-chain omega-3 polyunsaturated fatty acids (n-3 PUFA) may protect against...
GSE108254: Gain of function of the ATXN1-CIC complex drives cerebellar pathology in Spinocerebellar ataxia type 1 (part 1)
We isolated RNA from cerebella dissected from En1-Cre; Cicflox/flox and Cicflox/+ littermates at on...
GSE120370: The tissue factor-thrombin axis drives pancreatic ductal adenocarcinoma through tumor cell-derived PAR-1
RNA-Seq analysis reporting the transcriptional changes induced by treatment of mouse pancreatic duct...
GSE89378: Single-cell and bulk RNA-seq of sorted and micro-dissected mouse bone marrow and fetal liver cells
We here systematically studied the interaction network of bone marrow cells. To this end, we micro-d...
GSE87701: Effects of plasticizers (bisphenol A, bisphenol AF) and an herbicide in MCF7 human breast cancer cells
We studied alterations in gene expression profiles of the MCF7 human breast cancer cells caused by b...
GSE79519: The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions [RNA-seq]
STAT5 interacts with other factors to control transcription, and the mechanism of regulation is of i...
GSE87273: C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells
We established two HESC lines with a C9 mutation (SZ-ALS1, SZ-ALS3) from embryos, which were obtaine...
GSE88944: High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Ki...
GSE99309: Hepatic glucocorticoid receptor transcriptome profiling in normal and hypogonadal females
We report the hepatic glucocorticoid receptor transcriptome is reprogrammed in the absence of ovaria...
GSE87476: Mitotic Transcription and Waves of Gene Reactivation During Mitotic Exit
The genome is thought to be transcriptionally silent during mitosis. Technical limitations have prev...
GSE87694: Olfactory receptor accessory proteins play crucial roles in receptor gene choice
Mice with olfactry accessory protein RTP1 and RTP2 knocked out show severe bias in their olfactory r...
GSE80732 (mouse): Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq
All mammals develop from embryonic founder cells with the ability to generate all of the differentia...
GSE109895: Resident effector memory Tregs of the uterus regulate trophic functions during mouse early pregnancy
Regulatory T cells (Tregs) contribute to successful pregnancy by promoting maternal-fetal tolerance....
GSE132494: Dynamic Lineage Priming by ERK is Driven by Transcription Factor-Independent Enhancer Regulation [Med24_KO]
Extensive analysis if the means by which ERK affects transcription via enhancer regulation in mouse ...
GSE87290: RNA-seq of human peripheral blood mononuclear cells
Inflammatory cytokine responses to activation of innate immunity differ between individuals, yet the...
GSE99338: RNAseq analysis of wildtype and Nrf2-/- advanced lung tumors
Nrf2 plays a critical role in lung cancer. We investigated the gene expression profile in Nrf2 wildt...
GSE99352: Lower motor neuron transcriptomic analysis of a TDP-43 Q331K knockin mouse
Here we analyse transcriptome profiles from laser captured lower motor neurons between wild type, he...
GSE93331: Transcriptional profile of Krt15- and Krt15+ basal cells in mouse esophageal epithelium
We report different transcriptional profiles of Krt15+ and Krt15- basal cells in the mouse eosphagea...
GSE87299: Transcriptome changes in mouse livers upon Bmal1 or Nr1d1 knock out and interactome of lnc-Crot by 4C-seq
To explore the circadian regulations of Bmal1, we examined the transcriptome changes in mouse livers...
GSE92622: Expression profiling of mouse primary prostate cells from WT mice
By single-cell expression profiling and validation, here we report that both basal and luminal-local...
GSE124599: RNA-seq data for tumor tissues from mice fed with normal diet (ND) or high cholesterol diet (HCD) [Hep1-6]
To address how serum cholesterol affected tumor progression, C57BL/6J mice were placed on either nor...
GSE87315: Identification of PU. 1 target genes in mouse developing pro-B cells
We examined expression of PU.1 target genes in mouse developing pro-B cells by RNA sequencing (RNA-s...
GSE87821: Cooperation between the pioneer factor OCT4 and chromatin remodeller BRG1 matures transcription factor binding in embryonic stem cells [RNA-Seq]
Pioneer transcription factors are able to recognise and bind their motif sequences in inaccessible o...
GSE93796: mRNA-Seq of the CA1 hippocampal subregion from 3 month old animals injected with JQ1 (50mg/kg) i.p. and mRNA-Seq of CA1 of 8-10 month old APP/PS1-21 transgenic animals injected with JQ1 (50mg/kg) i.p.
Histone acetylation is essential for memory formation and provides a drug target to treat dementia. ...
GSE87519: RNA-Seq Analysis of Dose-Dependent TCDD-Elicited Hepatic Gene Expression in Male Mice
Dose-dependent hepatic gene expression was examined following repeated exposure (every 4 days for 28...
GSE80990: Mitochondrial retrograde signaling in mammals is mediated by the transcriptional cofactor GPS2 via direct mitochondria-to-nucleus translocation [GRO-seq]
As most of the mitochondrial proteome is encoded in the nucleus, mitochondrial functions critically ...
GSE87321: Complete atrio-ventricular canal defects in mouse hearts lacking G-protein receptor kinases
Combined ablation of all 3 cardiac-expressed GRKs in the developing mouse heart impaired Hedgehog/Sm...
GSE88943: Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines
The experiment was designed to display differential gene expression profiling in one lung epithelial...
GSE79796: Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency
We reported RNA-seq transcriptome profiling of WT and Cripto KO ESCEpiSC transition using the Illumi...
GSE90087: LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis
High levels of LMO1 expression synergizes with MYCN to accelerate neuroblastomagenesis, enhance dise...
GSE87824: Systematic identification and comparison of expressed profiles of lncRNAs and circRNAs in male and female germline stem cells
Male and female germline stem cells are critical for passing genetic information from generation to ...
GSE99454: Cellular responses to human cytomegalovirus infection.
Here we perform a systems analysis of the HCMV host-cell transcriptome across two cell-types. SOURCE...
GSE87344: Lamin-B1 contributes to the proper timing of epicardial cell migration and function during heart development
Gene expression analysis of wid type and Lmnb1-/- epicardial cells SOURCE: Joseph Tran Carnegie Inst...
GSE90111: Functional genomics of HDAC class-I specific inhbitor 4SC-202 in pancreatic cell lines [RNA-seq]
We examined transcriptome-wide effects of 4SC-202 in L3.6, BXPC3 and PANC1 cells as well as its effe...
GSE83312: ATAC-seq and RNA-seq of adult mouse rods and cones
Rod photoreceptors are specialized neurons that mediate vision in dim light and are the predominant ...
GSE87542: RNA-Seq Analysis of Dose-Dependent TCDD-Elicited Duodenal Gene Expression in Male Mice
Dose-dependent duodenal gene expression was examined following repeated exposure (every 4 days for 2...
GSE101678: RNA-seq data of intestinal epithelial cells and lamina propria dendritic cells
We report that Klebsiella pneumoniae promote Th1 cell induction in colon. To examine the influence o...
GSE90140: Molecular reprogramming of granulocyte/macrophage progenitor (GMP) clusters upon 5-Fluorouracil (5-FU) treatment
Single cell RNA Seq and bioinformatic analysis are used to study what processes are important for th...
GSE87554: Genome-wide transcriptional profiling of YAP target genes in human endothelial cells
Endothelial cell is the major cell type that senses and transduces mechanosignal generated by shear ...
GSE95027: ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5
To identify new Glioblastoma multiforme (GBM) therapeutic strategies, we previously performed genome...
GSE101748: Loss of Apela peptide in mice causes low penetrance embryonic lethality and defects in early mesodermal derivatives
Apela (also referred to as Elabela, Ende and Toddler) is a small signaling peptide that activates th...
GSE129827: Gene expression comparison of splenic virus-specific CD8 T cells after immunization with LCMV vector and treatment with IgG or aIFNAR1
Acute, transient IFNAR1 blockade induces a compensatory IFN-I response during the effector phase (da...
GSE87212: Targeting Phospholipase D4 attenuates kidney fibrosis by modulating immune system and activating proteases
Phospholipase D4 (PLD4), a single pass transmembrane glycoprotein, is amongst the most highly upregu...
GSE87387: RNA-seq of primary murine lung adenocarcinoma cells from KP and JKP mice
The AP-1 transcription factor c-Jun is required for Ras-driven tumorigenesis in many tissues. Surpri...
GSE88757: Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq
To identify targets post-transcriptionally regulated by miR-100 and miR-125b, we have performed AGO2...
GSE93904: Gene expression profile of CRC-derived HILEC
HILEC from CRC tissues isolated from human patients underwent RNA sequencing to define their express...
GSE87240: S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq)
S-adenosyl methionine (SAM) is a ubiquitous methyl donor that was reported to have chemo- protective...
GSE88840: Conversion of adult endothelial cells into immune-competent long-term repopulating authentic haematopoietic stem cells
The molecular pathways and microenvironmental cues that choreograph the conversion of endothelial ce...
GSE87720: Term placenta single cell transcriptome
We provide single cell transcriptomes from the placental-uterine interface. Tissue was collected at ...
GSE93293: Determination of Lsd1 function in inguinal white adipose tissue (ingWAT) by global transcriptome analysis
To investigate the role of Lsd1 in ingWAT we crossed mice harboring conditional Lsd1 alleles (Zhu et...
GSE87692: Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface
Organismal function is, to a great extent, determined by interactions among their fundamental buildi...
GSE88741: Gene expression changes in human melanoma cell lines compared to primary melanocytes
Gene expression changes in 3 human melanoma cell lines were compared to freshly isolated normal prim...
GSE140014: RNA-seq data of Spermatogonia cells of Tet1-ko and WT
We analyzed 3 repeats of 12 samples of mouse spermatogonia cells including 3-month-old WT and 3 mon...
GSE93847: STAT5BN642H is a driver mutation for T-cell neoplasia (RNA-Seq)
The most frequent mutation in STAT5B is the Asp642His (N642H) mutation that was found in >90 leukemi...
GSE89476: Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection
The role of astrocytes in innate immunity during viral infections of the central nervous system (CNS...
GSE85191: Widespread transcriptional pausing and elongation control at enhancers
Regulation by gene-distal enhancers is critical for cell-type and condition-specific patterns of gen...
GSE94641: Single cell RNA expression of mouse embryonic basal forebrain
Single-cell RNA-Seq RNA from medial ganglionic eminence at E11.5, E13.5, E15.5 or E17.5.; The "SAMPL...
GSE88998: Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles
Dendritic cell subsets purified from skin-draining lymph nodes of C57BL/6J mice following intraderma...
GSE106170: RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3
The nucleosome assembly proteins (NAPs) are histone chaperones with an important role epigenetic reg...
GSE89062: Integrated Transcriptomic and Proteomic Dynamics of Rituximab Treatment in B Lymphoblastoid Cells
The investigation aims to profile the molecular dynamics of Rituximab treatment in cells. Specifica...
GSE89532: RNAseq analysis of thymic CD4-CD8- double-negative (DN) invariant NKT cells from CD4+CD8+ double-positive (DP)-specific Rag2-conditional knock-out mice
We report the identification of DN NKT cells developed from DN stage thymocytes. We analyzed the gen...
GSE101437: Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE88764: RNA sequencing of the urethral epithelial progenitor cells
We will use micro-dissection to isolate cells from the embryonic mouse cloaca, and perform RNA-Seq a...
GSE84462: Inactivation of Ezh2 upregulates Gfi1 and drives aggressive Myc-driven Group 3 medulloblastoma [RNA-Seq]
The most aggressive of four medulloblastoma (MB) subgroups are cMYC-driven Group 3 (G3) tumors, some...
GSE88761: ERRa/ERRg KO heart gene expression analysis
ERRa and ERRg are essential transcriptional regulators of cardiac metabolism and functions. Here we...
GSE89918: miR-222 regulation of the tolerized LPS response
The purpose of this study is to determine the effect miR-221/222 have on LPS-induced gene expression...
GSE92762: RNA seq analysis of adipocyte precursor cells (APC) from Per3 KO mice
Understanding the differences in the transcriptome of adipocyte precuror cells in Per3 KO mice compa...
GSE135915: RNA-sequencing of mouse diabetic wounds treated with mast cell stabilizer MCS-01
To investigate global changes in gene expression patterns following treatment with DSCG or MCS-01 we...
GSE84324: Dynamics of chromatin marks and the role of JMJD3 during pancreatic endocrine cell fate commitment
Pancreatic endocrine lineages are derived from pancreatic progenitors that undergo a cell fate trans...
GSE87281: SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage
Spinal muscular atrophy is the leading genetic cause of infant mortality and is caused by homozygous...
GSE89899: Chronic nicotine differentially affects murine transcriptome profiling in isolated cortical interneurons and pyramidal neurons
Nicotine differentially affected subset of genes in Sst- and Thy1- neurons, which might contribute t...
GSE90534: Transcriptome analysis of the induced hepatocyte-like (iHep) cells
We have found three specific combinations of two transcription factors, comprising Hnf4alpha plus Fo...
GSE81275: A multi-step transcriptional and chromatin cascade underlies motor neuron programming (single-cell RNA-seq)
Direct programming via the overexpression of transcription factors (TFs) aims to control cell fate a...
GSE87767: mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription
mRNA cap addition occurs early during RNA pol II transcription, facilitating pre-mRNA processing and...
GSE89408: RNAseq study of synovial biopsies
Total RNA sequencing was performed on samples isolated from joint synovial biopsies from subjects wi...
GSE129992: RNA-sequencing of cultured young (2-3mos) and aged (20-22mos) mouse brain ILC2
We investigated how aging impacts the ILC2 population in the brain. Through RNA-sequencing of 2-week...
GSE81990: Dose-dependent metabolic reprogramming and differential gene expression in TCDD-elicited hepatic fibrosis
We have previously shown that in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-elicited NAF...
GSE98622: Transcriptome profile of a murine renal bilateral ischemia reperfusion model 2 hours to 12 months post injury
Acute kidney injury (AKI) is associated with an increased risk of chronic kidney disease (CKD). To e...
GSE89430: RNA-Seq Analysis of Dose-Dependent TCDD-Elicited Ileal Gene Expression in Male Mice
Dose-dependent ileal gene expression was examined following repeated exposure (every 4 days for 28 d...
GSE151250: next generation RNAsequencing from human hepatic stellate cells treated with GIPC shRNA reveals contribution of GIPC to hepatic fibrosis
next generation RNAseq data from human hepatic stellate cells with GIPC knockdown (GIPC shRNA) compa...
GSE94559: Hippocampus CA1 pyramidal cells Transcriptomic profile in WT and Fmr1 KO mice, using Wfs1-CreERT2:RiboTag:Frm1 knockout and wildtype mice
Comparing WT mice to a mouse model of mental retardation, this work identifies genes which display d...
GSE83253: Chromatin Remodeling Inactivates Activity Genes and Regulates Neural Coding
Activity-dependent transcription influences neuronal connectivity, but the roles and mechanisms of i...
GSE87511: Dietary interventions modulate global non-coding RNA expression: a role for microRNA-chromatin-mRNA crosstalk [Chd1KD_mRNA]
Using high-throughput deep sequencing we profiled coding and non-coding RNA expression in Hepa1-6 ce...