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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Although -synucleinis implicated in the pathogenesis of Parkinsons disease and related disorders, it...
In this study, we have utilized a single-cell RNA-Sequencing platform coupled with transgenic lineag...
The immune system employs two distinct defense strategies against infections: pathogen elimination t...
Control (Villin-CreERT2tg/0; Apcflox/+; Nleflox/+), ApccKO (Villin-CreERT2tg/0; Apcflox/flox; Nleflo...
Purpose: Epigenetic landscapes can shape physiologic and disease phenotypes. We used whole genome bi...
The inability of the adult mammalian heart to regenerate represents a fundamental barrier in heart f...
The development of high-throughput single-cell RNA-sequencing (scRNA-Seq) methodologies has empowere...
With the advent of potent second-line anti-androgen therapy, we and others have observed an increase...
Extra-embryonic mesoderm (ExM), the earliest cells that traverse through the primitive streak, give ...
The goals of this study were to compare two human chronic myeloid leukaemia cell lines. One is sensi...
Experimental V4020 is derived from VEEV TC-83, a vaccine with a long track record of use in lab and ...
Advances in genetics and sequencing have lead to a deluge of disease-associated and disease-causing ...
Folate deficiency causes widespread DNA breakages and is responsible for neural tube defect (NTD). H...
Tumor evolution from a single cell into a malignant, heterogeneous tissue remains poorly understood....
We try to explore the effect of RARRES1 on human podocyte, so we performed RARRES1 overexpression an...
Purpose: Chromodomain helicase DNA-binding (CHD) chromatin remodelers regulate transcription and DNA...
Memory antigen-specific CD4+ T cells against Chlamydia trachomatis are necessary for protection agai...
Cannabidiol (CBD) is an FDA approved drug for treatment of drug-intractable forms of pediatric epile...
Mitochondrial complex I regenerates NAD+ and proton pumps for TCA cycle function and ATP production,...
The goal of this study is to compare the differences in the global mRNA expression of WT and TAp63-/...
This study identified a novel compound reverses SIX1-mediated EMT and metastasis in breast cancer SO...
The efficiency of the repair process following ischemic cardiac injury is a crucial determinant for ...
Here, we investigated the role of mononuclear phagocytes associated nicotinamide adenine dinucleotid...
Understanding how uniquely human genetic changes altered developmental processes is essential to und...
We describe the novel synthesis Ag2S nanoparticles (NPs) by using a sonochemical method and reveal t...
Transcriptomic analysis of NRP1 KO and WT donor pMel-T cells recovered from B16-gp100 tumors SOURCE:...
Purpose: The goal of this study are to compare global gene expression profile in brown adipose tiss...
Tumors are complex ecosystems, in which malignant and non-malignant cells engage in continuous inter...
One of the health risks posed to astronauts during deep space flights is exposure to high charge, hi...
Both PIK3R1(Y657X) mutant and wild-type C57Bl/6J mice were maintained on chow until 16 weeks old, at...
Extra-embryonic mesoderm (ExM), the earliest cells that traverse through the primitive streak, give ...
Glioblastoma (GBM) is the most common and most aggressive intrinsic brain tumour in adults. Integrat...
To investigate the role of CHOP in the pathogenesis of liver disease due to Z alpha-1 antitrypsin in...
The RNA- and DNA-binding protein YBX1 is involved in various cellular processes. We here focused on ...
Rhes, a multifunctional striatal protein, regulates nuclear proteins and gene expression via SUMO-me...
This study aimed to investigate how many genes were regulated by hepatocyte ATF3. C57BL/6J mice were...
7- week old male and female, C57BL6 mice received subcutaneous injections of LLC1 lung adenocarcino...
Purpose: Compare the tumor outgrowth and immunology of an immunocompetent 4T1- and Py230-based intra...
Multiple myeloma (MM) is a hematologic malignancy tightly dependent on inflammatory bone marrow micr...
The goal of this study was to apply Next Generation Sequencing analyses to identify genes and pathwa...
Summary: RNAseq analysis of Axin2+ and Axin2- endometrial epithelial cells shows that Axin2+ cells h...
Deep sequencing datasets are used for gene expression analysis. Knockdown of circFAM120A by BSJ-gRNA...
Currently, it is unclear if all monocyte subsets exhibit osteoclastogenic potential. Furthermore, th...
We used an in-depth and parallel approach combining proteomics, transcriptomics and the drug pertuba...
Adipose tissue provides a defense against starvation and environmental cold. These dichotomous funct...
The goal of this study was to compare the transcriptional effects of sciatic nerve injury and spinal...
Connections between RNA polymerase II (RNAPII) transcription stress, R-loops, and genome instability...
To gain more insights into the functional significance of lnc-HLX-2-7, gene expression profiles were...
Purpose: RNA sequencing (RNA-Seq) analyses of articular cartilage obtained after DMM surgery in Osca...
In this study, we show that pediatric T-cell acute lymphoblastic leukemia (T-ALL) has an alternative...
The continuing spread of HIV/AIDS is predominantly fueled by sexual exposure to HIV-contaminated sem...
Distinct cell types emerge from embryonic stem cells through a precise and coordinated execution of ...
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
MYSM1 is a transcriptional regulator essential for HSC function and hematopoiesis. We established th...
MacroH2A histone variants have functions in differentiation, somatic cell reprogramming and cancer. ...
Immunity to fungal infections is mediated by cells of the innate and adaptive immune system. Activat...
We report the comparison of TLR9 agonist CpG and TLR4 agonist MPL alone and in combination on the ge...
LTi cells are part of the ILC family and essential for the formation of secondary lymph nodes within...
Placental insufficiency is implicated in the intrauterine infection-associated spontaneous preterm b...
Cancer stem cells (CSCs) are a minority population of cancer cells that display stem cell-like multi...
This study first reveals that Prp19 is a potential oncogene in neuroblastoma, which is significantly...
Neural control of visceral organ function is essential for homeostasis and health. Intestinal perist...
Genome-wide analysis of changes to mRNA transcript levels upon expression of YFV capsid in Huh7 cell...
We report TREX for simultaneous lineage tracking and expression profiling of dissociated cells from ...
Pluripotency is tightly regulated via versatile pathways and is crucial for the maintenance of stem ...
Abstract: Immunotherapy fails to cure most cancer patients. Preclinical studies indicate that radiot...
We developed a CHK1 inhibitor Prexasertib resistant strain of ovarian cancer cell line OVCAR5 in lab...
DmPGE2 predominantly interferes with IR-induced p53-downstream apoptotic gene expression at 1 h, and...
Murine pancreatic cancer cells (HY15549 cells) established from genetically engineered mouse models ...
Allele-specific expression (ASE) quantifies the relative expression of two alleles in a diploid indi...
To explore downstream gene expression profile of PKM2,we evaluated the transcriptome of GA- or SKN-t...
Inflammatory activation of endothelial cells is considered to be the first step in the development o...
Comparing the transcriptomic program induced by oleic acid to that of the pro-inflammatory arachidon...
Hematological malignancies are characterised by a block in differentiation, which is in many cases c...
Following liver injury, a subset of hepatocytes adopt features of biliary epithelial cells (BECs) in...
Type 1 interferon (IFN) plays a critical role in early antiviral defense and priming of adaptive imm...
This study first reveals that Prp19 is a potential oncogene in neuroblastoma, which is significantly...
We report RNA-seq data from hepatic mRNA on WT and PAI-1 heterozygous 21 week old mice. SOURCE: Doug...
Purpose: The goals of this study are to compare NGS-derived transciptomes from human melanoma cell l...
Regulatory T (Treg) cells require Foxp3 expression and induction of a specific DNA hypomethylation s...
Follicle stimulating hormone (FSH) regulates ovarian follicular development through a specific gene ...
Microglia are heterogeneous and ubiquitous CNS-resident macrophages that maintain homeostasis of neu...
Gene expression estimates detected by RNA-sequencing technology vary with the updates of reference g...
This study reports androgen-induced gene expression in granulosa cells of the ovary and provides a m...
The aim was to study the effect of shear stress on iPS-derived endothelial cells (iPS-EC). iPS-ECs w...
During the natural progression of Non-small-cell lung cancer (NSCLC), tumor cells evolve progressive...
Identification of gene expression changes in cortex-specific Sufu knockout mice SOURCE: Samuel Pleas...
Strong evidence supports the tumor immune landscape as a determinant of patient responses to immunot...
Neural control of visceral organ function is essential for homeostasis and health. Intestinal perist...
In our study, We found that exosomal transfer occurred from highly metastatic nasopharyngeal carcino...
Exploration into the dynamic process of adipogenesis in MEF cells via transcriptome analysis SOURCE...
Anterior mesoderm (AM) and definitive endoderm (DE) progenitors represent the earliest embryonic cel...
Neural control of visceral organ function is essential for homeostasis and health. Intestinal perist...
Purpose: The function of Prom1, a penta-transmembrane glycoprotein which is a used as cancer stem c...
Chronic stress contributes to the development of psychiatric disorders including anxiety and depress...
Keratinocyte-specific RIPK1 deficiency causes skin inflammation due to ZBP1-induced necroptosis. RNA...
The objective of this study is to identify molecular determinants of DAC response in gliomas SOURCE:...
Somatic cell nuclear transfer (SCNT) enables gaining of totipotency by reprogramming nuclei of termi...
Tumor cells rely on glutamine to fulfill their metabolic demands and sustain proliferation. The elev...
Here, we describe the identification and characterization of p38 as a novel regulator of DUX4 expres...