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Sequencing-based assays page 13
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GSE87758: Intersectionally labeled Drd2-Pet1 single-neuron RNA-seq
Single-neuron transcriptome profiles of Dorsal Raphe neurons marked by a history of expression of Dr...
GSE88777: Deep Sequencing analysis of the total RNA state and the polyadenylation state of mRNAs in Scrambled or CNOT7 knockdown neurons
Differential thermal elution over poly(U) agarose was used to identify mRNAs that underwent a change...
GSE157077: Reshaping Circadian Metabolism in the Suprachiasmatic Nucleus and Prefrontal Cortex by Nutritional Challenge
We compared the transcriptome of Suprachiasmatic Nucleus in C57BL/6J mice fed a high-fat diet or nor...
GSE87608: Next-Generation Sequencing Supports Quantitative Analysis of Wild Type and Runx2+/- Calvarial Transcriptomes With or Without Administration of MS-275
Because insufficiency of Runx2 limits skeletal growth, there is a great deal of effort to activate R...
GSE79729: RNA-seq analysis of in vivo- and in vitro-produced mouse oocytes
The female germline undergoes a unique line of differentiation processes that endows totipotency to ...
GSE95649: Mir-132/212 shapes age-dependent transcriptome and is required for binocular matching of orientation preference and depth perception.
We performed RNA sequencing and smallRNA sequencing experiments on visual cortex tissues from three ...
GSE109903: Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer [RNA-seq]
Transcriptome levels of matched patient-derived xenograft (PDX) in vitro-in vivo models. SOURCE: Tou...
GSE88779: Mouse Pancreatic Islet Maturation Time Series
Beta cells are the sole source of insulin in our body, yet we do not understand how they mature into...
GSE86151: Targeting the Creatine Kinase Pathway in EVI1-Positive Acute Myeloid Leukemia
Purpose: Identify new targets in EVI1-Positive Acute Myeloid Leukemia; Methods: Treatment with cyclo...
GSE135690: Impact of sevoflurane priming on B16F10 transcriptome after in vivo growth
Murine skin melanoma cell line B16-F10 (ATCC no. CRL-6475) was obtained from the national standard r...
GSE119441: The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice
We reported the hepatic gene expression profiling in mice treated by perfluorooctanoate (PFOA) and h...
GSE98003: Bptf maintains chromatin accessibility and the self-renewal capacity of mammary gland stem cells [RNA-Seq]
Chromatin remodeling is a key requirement for transcriptional control of cellular differentiation. H...
GSE100332: Next-generation sequencing measuring ribosome mRNA occupancy and translation efficiency in CD4+ T cells isolated from Mettl3 KO and WT mice
CD4+ Naive T cells were isolated by StemCell CD4+ T cell isolation kit of spleen and lymph nodes WT ...
GSE89989: RNA-seq data from T cells in vitro
Comparison of athymic T cells generated in vitro with iPSC-derived recent thymic emigrant (iRTE) gen...
GSE93374: A Molecular Census of Arcuate Hypothalamus and Median Eminence Cell Types
Drop-seq and single cell sequencing of mouse arcuate nucleus and median eminence SOURCE: Linus,Tzu-Y...
GSE94239: RNAseq analysis of GL261 GDC and mNS GSC transcriptome
We compare the gene expression profile between GL261 glioma differentiated cells (GDC) and mNS Neuro...
GSE90013: HBEC-shp53-PCHD7
We studied the effects of ectopic expression of Protocadherin 7 (PCDH7) on Human Bronchial Epithelia...
GSE95056: Differential requirement for functional telomeres in neurons
RNAseq was perfomed in control and TRF2-DCVX-cre mice to evaluate the effect of telomere dysfunction...
GSE93379: Gene expression profile (RNA-seq) of hypophysectomized male mouse liver treated with a single pulse of growth hormone (GH)
We investigated the effects of a single pulse of growth hormone on the transcriptional activation of...
GSE90929: Transcriptional changes in the primary somatosensory cortex upon sensory deprivation
Experience-dependent plasticity (EDP) is essential for anatomical and functional maturation of senso...
GSE89991: RNA-Seq in PWS iPSC-derived neurons
Transcriptional analysis of PWS iPSC-derived neurons compared to unaffected controls SOURCE: Lisa,Co...
GSE90468: Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1]
Comparing the gene expression in control siRNA samples and HIC1 siRNA samples SOURCE: Sini Rautio Aa...
GSE99479: A class of GATA3 mutation reprograms the breast cancer transcriptional network through gain and loss of function
A pioneer transcription factor, GATA3, is one of the most frequently mutated genes in breast cancer,...
GSE97215: Genetic-to-epigenetic Therapy for Pancreatic Cancer
We utilized RNA-Seq to define molecular markers for the effect of chaetocin and MLN8237 combination....
GSE93179: Tau-P301L sorted cell types
Mice of indicated sexes and genotypes were perfused and their brains dissected and dissociated. Cell...
GSE94685: RNA-sequencing of lung ECs isolated at P5 from mice with EC-specific deletion of LATS1/2 and LATS1/2;YAP/TAZ
To investigate the role of Hippo-YAP signaling in angiogenesis, we performed RNA-sequencing by using...
GSE93594: Transcriptome-wide identification of CELF2 functional targets in T cells
CELF2 is a critical regulator of alternative splicing during T cell development and during stimulati...
GSE98877: Commensal microbiota modulate gene expression in the skin
Background: The skin harbors complex communities of resident microorganisms, yet little is known of ...
GSE99265: MicroRNA-183 cluster continuously scales mechanical pain sensitivity by regulating basal and neuropathic pain gene pathways.
Nociception is protective and prevents tissue damage but can also facilitate chronic pain. If a gene...
GSE92892: Generation of muscle stem cells from pluripotent stem cells
We have developed a method to generate muscle stem cells from pluripotent stem cells via teratoma fo...
GSE80804: A Pro-Asthmatic IL-4 Receptor Allele Promotes Airway Inflammation by Programming TH17 Cell-Like Regulatory T cells
Mechanisms by which regulatory T (Treg) cells fail to control inflammation in asthma remain poorly u...
GSE90889: Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle
We did the RNA-seq analysis to examine the global impact of Nicotinamide (NAM) on hiPSC-derived RPE ...
GSE89132: Study on the effects of cytoskeletal modifying compounds on stem cell differentiation
We report genome-wide expression changes that occur in mouse bone marrow-derived mesenchymal stem ce...
GSE93230: Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo
A comparison of the mRNAs analysis in lactation mammary myoepithelial cells (GFP+/GFP-) and brown ad...
GSE112261: RAC-GEF function as a critical factor in intestinal tumourigenesis
Here we investigate the transcription changes in the murine intestine 4 days following loss of APC u...
GSE93610: Time-course expression data from HEK293RAF1:ER cells stimulated with 4OHT and labelled with 4SU
We integrate experimental data and mathematical modelling to unveil how ERK signal duration is trans...
GSE93385: Differential responses of human fetal brain neural stem cells to Zika virus infection
Purpose: The goal of this study is to investigate the effect of Zika virus infection on neural stem ...
GSE95154: Gene expression profile of neurons expressing protein kinase C (PKC) or somatostatin (SST) in the central amygdala (CEA) of mice
Circuit neuroscience has made great progress by linking neuronal function to marker gene expression,...
GSE125268: RNAseq profiling of miR-132/212-deficient CD4+ T cells activated in vitro and in vivo.
Transcriptomic profiling of miR-132/212-deficient and WT CD4 T cells isolated from spleens of L dono...
GSE93070: Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [exoRNA-Seq]
The goal of this study is to investigate if endogenous RNA in exosomes activates RIG-I through unshi...
GSE93598: Genome-wide analysis reveals dual roles for Ikaros in regulation of macrophage chromatin state and inflammatory gene expression [RNA-seq]
Macrophage activation by bacterial LPS leads to induction of a complex inflammatory gene program dep...
GSE93057: RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins
Primary breast cancer xenografts SOURCE: Jessica Finlay-Schultz (jessica.finlay-schultz@ucdenver.edu...
GSE139905 (mouse): Transcriptome upon PDXK knock-out in mouse and human leukemic cells
To study transcriptomic changes upon PDXK knock-out in mouse and human leukemic cells SOURCE: Yu-Jui...
GSE94852: Radiation Induced Pulmonary Fibrosis as a Model of Progressive Fibrosis: Contributions of DNA Damage, Inflammatory Response and Cellular Senescence Genes
Utilizing an established model of Radiation Induced Pulmonary Fibrosis, low input RNA sequencing was...
GSE82002: The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryo
Oocytes develop the competence for meiosis and early embryogenesis during their growth. Setdb1 is a ...
GSE83697: Tbet regulates the transcriptional programming of Be1 B cells.
To investigate the role of Tbet in B cell differentiation to "effector-like" antibody secreting cell...
GSE93072: Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [patients RNA-Seq]
The goal of this study is to investigate if endogenous RNA in exosomes activates RIG-I through unshi...
GSE88778: Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets
Beta cells are the sole source of insulin in our body, yet we do not understand how they mature into...
GSE87487: Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers
Purpose: RNAseq was used to look in donor allografts for genes encoding cytokine receptors specific ...
GSE87785: Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer
To identify tumor suppressive microRNAs repressed by DNA hypermethylation in gastric cancer (GC), we...
GSE98041: Diurnal liver transcriptome in wt and nono-/- mice
The liver circadian transcriptome results from the combined action of a circadian clock and feeding/...
GSE93071: Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [RNA-Seq]
The goal of this study is to investigate if endogenous RNA in exosomes activates RIG-I through unshi...
GSE99944: Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells
We report the effect of FDA approved digoxin treatment (50nM for 48h) on the gene expression and alt...
GSE119499: Comparative transcriptomic analyses provide insights into key genes involved in niche-associated functions of primary murine LEC and BEC in homeostasis
Purpose: The goal of this study is to compare the transcriptome profiles of freshly isolated primary...
GSE93143: Full-coverage landscape of extracellular RNAs, coding and non-coding, secreted by human glioma stem cells
Communication between glioblastoma brain tumor (GBM) and its microenvironment alters the parameters ...
GSE87849: The Nature and Nurture of Cell Heterogeneity: Accounting for Macrophage Gene-environment Interactions with Single-cell RNA-Seq
Background: Single-cell RNA-Seq can be a valuable and unbiased tool to dissect cellular heterogeneit...
GSE119484: Hif-1alpha deletion leads to adverse treatment efficacy in a mouse model of MLL-AF9 driven AML
This report explores the effect of Hif-1alpha deletion, using a conditional mouse model, together wi...
GSE93153: The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and is Counteracted by the HBV X Protein Shortly after Infection
RNA-Seq analysis of HBV-infected primary human hepatocyte SOURCE: Li Li (li.li@gilead.com) - Gilead...
GSE84468: Tumor-derived prostaglandin E2 promotes p50 NF-B-dependent differentiation of monocytic MDSC.
Myeloid-derived suppressor cells (MDSC) include immature monocytic (M-MDSC) and granulocytic (PMN-MD...
GSE87899: Identification of Novel Targets of Diabetic Nephropathy Using RNA-seq
Diabetic nephropathy (DN) is a major complication of type 1 and type 2 diabetes and may lead to kidn...
GSE94814: RNA-seq analysis of WT vs. Reck vascular KO P0 mouse brains
We examined, compared, and analyzed the transcriptome profile (RNA-seq) of WT vs Reck vascular KO (R...
GSE87531: Effects of aged garlic extract (AGE) and FruArg on lipopolysaccharide-induced genetic response in microglial cells using gene expression profiling
We hypothesized that aged garlic extract, and a pure compound from it, FruArg, can repress the genet...
GSE95601: Olfactory stem cell differentiation: horizontal basal cell (HBC) lineage
The lineage of the horizontal basal cells (HBC) stem cells and other Sox2eGFP-positive cells from th...
GSE95852: Gene expression profiles in retinas from miRNA183/182/96 cluster knockout mice versus wild type controls by RNA-seq
Retinas from various developmental stages at postnatal p5, p11, and p27 from miRNA183/182/96 cluster...
GSE93585: Transcriptome analysis of the effect of DAPT in GHMT-induced cardiac reprogramming
The purpose of this experiment is to anlyze the transcriptomic changes associated with Notch inhibit...
GSE88802: Novel metastatic models of human esophageal adenocarcinoma highlight the importance of E-cadherin in cancer metastasis
We report the identification of FLO-1, and derivation of its isogenic companion FLO-1LM, as two spon...
GSE92340: Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B
In order to obtain an overview of gene expression changes in CHMP2B-dependent frontotemporal dementi...
GSE94982: Landscape of translation in mouse tissues
We used parallel ribosome profiling and RNA sequencing to investigate the tissue-specific translatio...
GSE87517: Immune escape in breast cancer during in situ to invasive carcinoma transition
To dissect mechanisms of immune escape during breast tumor progression, we analyzed the composition ...
GSE90813: Single cell analysis of SFTPC+ cells and CPM-high progenitor cells derived from human induced pluripotent stem cells (hiPSCs)
We stepwisely induced SFTPC+ cells from hiPSCs via CPM-high progenitor cells with or without cocultu...
GSE88858: RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets
The goal of this study is to compare the gene profiling of human blood BDCA-1+ cDCs, blood BDCA-3+ c...
GSE92865: Single-cell RNA-seq of Lgr5-eGFP+ intestinal stem cells upon Wnt and R-spondin modulation in vivo
We report the transcriptomic alterations of Lgr5-eGFP+ intestinal stem cells upon Wnt and R-spondin ...
GSE101623: The neuropeptide Neuromedin U stimulates innate lymphoid cells and promotes type 2 inflammation [ILC2 and ILC3]
The type 2 cytokines interleukin (IL)-4, IL-5, IL-9 and IL-13 play critical roles in stimulating inn...
GSE95631: Programed cell removal of Neutrophils regulated by calreticulin
RNA seq analysis for pathwayidentification to identify SOURCE: Kristopher,David,Marjon (kdmarjon@st...
GSE88905: Genome-wide effect of AML engraftment on bone marrow endothelial cells
We analysed the transcriptional signature in endothelial cells extracted from the bone marrow of mic...
GSE101745: FGF-13 promotes metastasis in triple-negative breast cancer
To define the molecular regulators of metastasis of triple-negative breast cancer, we conducted a ri...
GSE109936: Establishment of novel atopic dermatitis model by Nestin-cre mediated Ikk2 deficiency
To generate novel atopic dermatitis model, we used Nestin-cre mediated Ikk2FL/FL mice. Nestincre-med...
GSE94893: RNA-seq analysis in dermis and epidermis of WT (control), LSL-Shh (Shh overexpression in epidermis), and E14.5d skin
We found Shh overexpression in epidermis can induce hair follicle neogenesis in wounded skin. We ana...
GSE92377: bulk cell RNA-seq of Lgr5+ ISCs with in vivo Rspo GOF and LOF
sorted Lgr5-eGFP+ cells under conditions of in vivo Rspo manipulation in reporter mice, SOURCE: Xiao...
GSE92434: RNA- and ATAC-seq data of Wt, Ebf1-KO and Pax5-KO FL-ProB-cells.
EBF1 and PAX5 are crucial factors for B-cell development. Knock down of either factor leads to an ar...
GSE93590: Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration
Inhibition of FOXO1 activity in kidney microvascular endothelial cells improves angiogenesis SOURCE:...
GSE90519: Basal-A Triple Negative Breast Cancer Cells Selectively Rely on RNA Splicing for Survival
Development of targeted therapies for triple-negative breast cancer (TNBC) has failed at least in pa...
GSE90657: Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402
RNA sequencing was performed on biological triplicates of HSB2 and RPMI8402 cells treated with 100nM...
GSE95617: Transctriptional profiling of murine hematopoietic stem and progenitor cells upon -glucan administration
Objective: Transcriptional profiling of murine HSPC in response to -glucan-induced innate immune tr...
GSE90133: Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma
The epithelial-to-mesenchymal transition (EMT) process in cancer enables the migratory and invasive ...
GSE81875: CPEB4 prevents hepatic steatosis [RNA-Seq]
The Cytoplasmic Polyadenylation Element Binding (CPEB)-family of RNA-binding proteins regulates pre-...
GSE88737: The profile of long non-coding RNAs in mouse testis and sperm after exposure to cadmium
Increasing evidences have shown that cadmium could caused male infertility. However, the exhaustive ...
GSE92887 (human): Impact of HypERrlnc Knockdown on the human pericyte transcriptome
Pericytes are essential for vessel maturation and endothelial barrier function. Long non-coding RNAs...
GSE104139: Defining transcription factor networks that govers SCC growth [RNA-Seq]
Differential gene expression analysis were performed between Pitx1 silenced SCC cells and controls i...
GSE106471: IRF3 and type I interferons fuel a fatal response to myocardial infarction [bulk RNA-Seq]
Interferon regulatory factor 3 (IRF3) and type I interferons (IFNs) protect against infections1 and ...
GSE90684: IGF2BP proteins Enhance mRNA stability
To evaluate the effect of IGF2BPs on mRNA stability and gene expression output, we conducted RNA-seq...
GSE90961: Comparison of Pax6 alpha enhancer Cre-Rblox/lox retinas to Pax6 alpha enhancer Cre-Rblox/lox TET-MYCN retinas at PND12
The most frequent focal alterations in human retinoblastoma are RB mutation and MYCN amplification. ...
GSE92894: The efficiency of Xist-mediated silencing of X-linked and autosomal genes is determined by the genomic environment
Xist is indispensable for X chromosome inactivation (XCI) in female mammalian cells. However, how Xi...
GSE87341: In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells
The in vitro derivation and propagation of spermatogonial stem cells (SSCs) from pluripotent stem ce...
GSE108177: Total RNA-seq of cancer cells with inhibition of DNA and/or histone methylation
Endogenous Retroviruses (ERVs) silencing mechanism depend on DNA methylation, heterochromatin confor...
GSE84996: Ionic immune suppression within the tumour microenvironment limits T cell effector function
Tumours progress despite being infiltrated by effector T cells. Tumour necrosis is associated with p...
GSE89136: Loss of imprinting mutations define both distinct and overlapping roles for misexpression of IGF2 and H19 lncRNA
Imprinted genes occur in discrete clusters that are coordinately regulated by shared DNA elements. H...
GSE95168: H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Mouse RNA-Seq]
Gain-of-function mutations in histone 3 (H3) variants are found in a large proportion ofpediatric hi...
GSE94099: RNA-seq analysis of the effects of BCL6-inhibiting and BCL6-degrading compounds in lymphoma cell lines
The goal of this experiment is to measure the changes in gene expression induced by small molecules ...
GSE121117: SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors
We performed RNA sequencing analysis using NextSeq500 to identify drivers that mediate feedback RAS ...