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Sequencing-based assays page 14
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GSE86235: Voluntary running triggers VGF-mediated oligodendrogenesis to prolong the lifespan of Snf2h-null ataxic mice
Exercise enhances cognitive function and slows progressive neurodegenerative disease. While exercis...
GSE49321 (human): Improved Smart-Seq for sensitive full-length transcriptome profiling in single cells
Improved Smart-Seq for sensitive full-length transcriptome profiling in single cells. SOURCE: Rickar...
GSE92539: The histone code reader Spin1 controls skeletal muscle development
We report developmental defects in Spin1(Myf5-Cre) mice, in which Spin1 is ablated in skeletal muscl...
GSE81181: Gene expression analysis to identify Runx1 target genes in GMP, MEP and Gene expression signature of Runx1/ lin- sca- kit+ CD105- CD16/32+ CD150+ (XMP) progenitors
We report the application of single-molecule-based sequencing technology for high-throughput profili...
GSE88850: Assessing characteristics of RNA amplification methods for single cell RNA sequencing
We conducted a large-scale control experiment to assess the transfer function of three scRNA-seq met...
GSE109885: The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines]
RNA-Sequencing Analysis was performed on 7 Head and Neck Squamous Cell Carcinoma Cells Lines in orde...
GSE89796: Identifying deer antler proliferation and mineralization genes using comparative RNA-seq
Purpose: The goal of this study is to compare (RNA-seq) transcriptomes of in vitro cultured human bo...
GSE85412: The mechanism of restoration ovarian function using female germline stem cell
Germ stem cells are the only stem cells which can produce gametes in vivo. Recently, accumulating ev...
GSE88856: JNK promotes epithelial cells anoikis by transcriptional and post-translational regulation of BH3-only proteins
Developmental morphogenesis, tissue injury, and oncogenic transformation can cause the detachment of...
GSE90136: Transcriptome analysis of Cdc73 deletion in AML cells
The Polymerase Associated Factor (PAFc) complex is an epigenetic regulating complex that has been sh...
GSE90654: RNA-seq analysis of RNA from DBA/2J retinal ganglion cells
RNA-seq analysis from young and pre-glaucomatous DBA/2J retinal ganglion cells and control (age and ...
GSE121122: Selective eradication of leukemia cells with reprogramming factors (RNA-Seq)
We used RNA-seq to evaluate the global programme of gene expression after Dox inducible Yamanaka fac...
GSE92914: RNA-Seq analysis of human colorectal cancer with liver metastasis
Nine specimens from three colorectal cancer (CRC) patients including adjacent normal tissue, primary...
GSE97110: Role of TERRA lncRNA during epithelial-to-mesenchymal transition
We analyzed the contribution of TERRA lncRNA in an invitro model of epithelial-to-mesenchymal transi...
GSE92562: Post-transcriptional regulation of adult CNS axonal regeneration by Cpeb1
Profiling of injury response of the localized transcriptome from wild-type and Cpeb1 knockout neurit...
GSE93787: Diverse Non-Genetic Allele Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain [HybridMouseDRN]
Determine allele level expression in hybrid mice of different ages SOURCE: Christopher Gregg (chris....
GSE90848: Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices (SC RNA-Seq)
Adult tissue stem cells (SCs) reside in niches, which through intercellular contacts and signaling, ...
GSE112482: Celll type specific gene expression from healthy human lung tissue infected with mycobacterium tuberculosis (ILC).
We have investigated the initial responses in human lung tissue explants to Mtb infection, focusing ...
GSE94969: Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5)
We report that engagment of TLR10 via the 5C2C5 anti-TLR10 mAb causes differential expression is a s...
GSE96592: DLK inhibitor treated Optic nerve crush
RNA was purified from retinas following crush in the presence of vehicle or DLKi; The "SAMPLE_ID" sa...
GSE92979: The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells
We report the function of Flightless I involved in the overall nuclear export, and genome-wide trans...
GSE92589: Tsc2 KO cells have a transcriptional signature found in bladder tumors with TSC1/2 deficiency and that is corrected by sirolimus and includes Lgals3 overexpression
Use RNA-seq to obtain transcriptional signature of Tsc2 KO neonatal mouse dermal fibroblasts +/- sir...
GSE95280: The hypoxic landscape of melanoma
Micro-environment played an important role in the disease progression and overall survival. More rec...
GSE85221: Developmental Exposure to 2,2,4, 4 Tetrabromodiphenyl Ether Induces Long-Lasting Changes in Liver Metabolism in Male Mice
Polybrominated diphenyl ethers (PBDEs) were used as flame-retardant additives in a wide range of pol...
GSE96939: Role of NRROS in microglia and perivascular macrophages in the brain
Mice deficient in NRROS exhibit neurological phenotype similar to ALS. Our previous work showed that...
GSE88888: Monocyte transcriptome differences in early stage Parkinsons disease patients
Recent studies suggest that the activation of the innate immune system is an integral part of Parkin...
GSE89207: Candidate Gene Identification Through RNA-Seq Analysis of (TRAMP x J:DO) F1 Primary Tumors
RNA-seq analysis of 195 randomly selected (TRAMP x J:DO) F1 prostates that had been harvested at exp...
GSE96598: Expression pattern in dSG knockout mutant mice and effect of treatment with ifetroban
We sequenced RNA from left ventricle of dSG knockout and wild type mice treated with vehicle or ifet...
GSE95363: A Comparison of theSexually Dimorphic DexamethasoneTranscriptomeinMouse CerebralCortical and HypothalamicEmbryonicNeuralStemCells
We used RNA-Seq analysis to identify thesexually dimorphic dexamethasone regulated gene expression p...
GSE89115: Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage
Alpha-synuclein (aSyn) is widely portrayed as the main culprit on Parkinsons Disease (PD) pathophysi...
GSE98674: Combinatorial Signal Preception in the BMP Pathway
These data consist of an expression survey of three receptor cell lines and the parental cell types ...
GSE114960: Dietary fat, but not dietary protein or carbohydrate (sucrose), regulates energy intake and causes adiposity in mice
Purpose: Obesity is a global health issue. To investigate if protein and fat contents of the diets h...
GSE103549: Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells
Primary human skeletal muscle cells (Lonza) were treated with LLC1 conditioned medium, LLC1 conditi...
GSE79423: Temporal regulatory interactions of lipid metabolism and inflammation in defining macrophage inflammatory phenotype
Systematic analyses of the temporal dynamics of transcriptomes and chromatin landscapes of macrophag...
GSE94241: Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq]
Aberrant gene expression is a hallmark of acute leukemias. However, therapeutic strategies for its b...
GSE96938: Gene expression of mouse brain and mouse microglia in NRROS WT and NRROS KO animals
Mice deficient in NRROS exhibit neurological phenotype similar to ALS. Our previous work showed that...
GSE104956: LEAP2 is an Endogenous Antagonist of the Ghrelin Receptor
Bariatric surgery, an effective treatment for obesity and diabetes, leads to profound remodeling of ...
GSE96966: RNA-seq analysis comparing normal mouse melanocyte stem cells to the melanoma tumor derived from them upon Braf:Pten mutations
We found that mouse melanocyte stem cells give rise to melanoma whose signatures highly mimicks huma...
GSE89732: RNA-sequencing of B cells in the absence of Moz or c-Myb
Humoral responses of mice specifically deleted for Moz (a histone acetyltransferase) or c-Myb (a tra...
GSE96627: Transcriptomic response to 24-hour food deprivation in four hypothalamic nuclei
The hypothalamus has an established role in the central control of energy homeostasis. In this stud...
GSE97224: Expression profiles of restoration of BAP1 in a BAP1 deficient cell line
RNA-seq of UPMM3 with restoration of BAP1 and BAP1 mutant proteins. Cell line UPMM3 contains a frame...
GSE89161: Analysis of Wild Type and B7-H4-/- leukemia initial cells Transcriptomes
The goal of this study are to find the abonormally expressed genes of B7-H4-/- leukemia inital cell...
GSE89952: Transcriptome analysis of murine T-cell lymphoblastic lymphomas induced by HrasG12V, p53 KO and CIC loss-of-function
RNA sequencing of T-ALL tumors derived from genetically modified mouse models: CIC loss-of-function,...
GSE87848: RNA-seq analysis of livers of C57BL/6 mice upon antagomiR-122 and CL316243 treatment
Purpose: miR-122 plays a role in lipid metabolism in the liver. The goal of this study is to search ...
GSE100727: Pitx1 directly controls the core limb development program to implement hindlimb identity [RNA-Seq]
Pitx1, critical regulator of a limited hindlimb-specific gene network, targets the limb development ...
GSE96054: Time-course analysis of astrocyte-specific RNA-seq in two severities of spinal cord injury
RNA-seq analysis of astrocytes following spinal cord injury demonstrated an autologous injury-induce...
GSE81149: RNASeq of MLL-AF9 cells transduced with scramle shRNA or BRD4 shRNA in combination with DMSO or SGC0946
Central to the molecular pathogenesis of MLL leukaemia is the abnormal co-optation of members of tra...
GSE88954: Identification of glucocorticoid-dependent circadian genes in the cochlea
The cochlea possesses a robust circadian clock machinery that regulates auditory function. How the c...
GSE89108: Integrative analysis of translatome and transcriptome of adipocytes
To systemically determine the translational control of gene expression in adipose, we performed ribo...
GSE81103: Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice
Truncating CHD8 mutations are amongst the highest confidence risk factors for autism spectrum disord...
GSE90053 (human): Species-Specific Developmental Timing is Maintained by Pluripotent Stem Cells Ex Utero
We performed whole transcriptome RNA sequencing experiments on two sets of differentiation time cour...
GSE96059: Next Generation sequencing and quantitative transcriptomic analysis in -77+/+ and -77-/- erythroid precursors
Gene expression profiles of sorted erythroid precursors from E14.5 wild-type (WT) and -77 enhancer k...
GSE82072: Next Generation Sequencing of megakaryocyte-erythrocyte progenitor cells (MEPs) with or without mutations in JAK2 and Ezh2
Comparison of mRNA expression profiles of MEPs with or without mutations in JAK2 and Ezh2 by RNA seq...
GSE150809: Transcriptomes of H1650 cells with and without SETD2 depletion
RNA sequencing of H1650 cells with and without SETD2 depletion to identify SETD2-regulated genes SOU...
GSE99030: Choroid plexus tertiary lymphoid structures in lupus: a novel neuro-immune interface
The central nervous system manifestations of systemic lupus erythematosus (SLE) remain poorly unders...
GSE104775: TREM2 Gene Dosage Increase Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimers Disease Models
TREM2 BAC transgenic mice with elevated expression of human TREM2 in microglia under its endogenous ...
GSE96643: RNA_seq and Ribo_seq analyses of control and CPT-treated MCF7 cells
We used RNA-seq and Ribo-seq analyses to examine the effect of CPT treatment of translation efficien...
GSE88931: Human embryonic stem cells do not change their X-inactivation status during differentiation [RNA-Seq]
Female human ESC-lines can carry active X-chromosomes (Xa) or an XIST-RNA-coated inactive X-chromoso...
GSE92238: RNA-seq transcriptonal profiling in whole hippocampus in WT and Arid1b+/- mice
There is growing evidence for the involvement of ARID1B, a SWI/SNF ATP-dependent chromatin remodelin...
GSE87556: DERARE RNA-seq
We analyzed the transcriptome of LT-HSCs sorted from wildtype and DERARE knockout mice. We aim at id...
GSE92725: AMPK signaling for nave pluripotency [Hs]
We show activation of AMP kinase (AMPK) with single chemical compounds can endow nave pluripotency. ...
GSE89497: Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta
In this study, we isolated human villous stromal cells (STRs), CTBs, the STB, and EVTs at the first ...
GSE97435: USP7 controls the oncogenic transcriptional circuitry and is a novel therapeutic target in T cell leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by...
GSE82043: Itaconate links inhibition of succinate dehydrogenase with macrophage metabolic remodeling and regulation of inflammation
Remodeling of the tricarboxylic acid (TCA) cycle is a metabolic adaptation mechanism accompanying in...
GSE97445: Tracheal gene expression after Wls deletion
Wls is required for patterning of the developing trachea SOURCE: Debora Sinner (debora.sinner@cchmc....
GSE97828: RNA expression in anterior nasal septum cartilage of wildtype and Fgfr2+/S252W Apert syndrome model mice at embryonic day (E)14.5.
The nasal capsule cartilage of Apert Fgfr2+/S252W mice increases in size compared to wildtype carti...
GSE97729: Induction of Cardiomyocyte Proliferation [tm-683-mouse]
Isolated adult cardiomyocytes from alpha-MHC MADM mice treated with 4 cell cycle genes to induce car...
GSE97911: Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type (WT) HSCs and NHD13+ MDS HSCs Transcriptomes
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE87558: Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes
Transplantation of genetically corrected hepatocytes is an attractive alternative to liver transplan...
GSE89737: Rapid molecular profiling of defined cell types using viral TRAP
Translational profiling methodologies enable the systematic characterization of cell types in comple...
GSE96608: Interplay between genome topology and gene regulation during somatic cell reprogramming [RNA-seq]
Studies of genome topology, chromatin state and transcriptome dynamics during highly-efficient somat...
GSE100764: Spindle-localized mRNA translation mediated by CPEB1 and CPEB4 controls mitotic progression
Sequencial functions of CPEB1 and CPEB4 in the localization of repressed mRNAs to the mitotic spindl...
GSE97732: Divergent mechanisms of EZH1 regulation of heart development and regeneration [RNA-Seq]
RNA-seq for DKO, E1KO, E2KO and WT E12.5 heart revealed that EZH1 and EZH2 play a partially redundan...
GSE105019: Gene expression analysis of human liver progenitor-like cells in culture
To compare the global expression profiles among primary human hepatocytes and liver progenitor-like ...
GSE94574: A Cross-Species Approach Identifies MELK as a Potential Therapeutic Target in Prostate Cancer
Genetically engineered mouse models of cancer represent valuable biological tools that can be used t...
GSE97766: Gene Expression Profiling of Gemcitabine, Genistein and Combinatorial Effects on Pancreatic Cancer Cell Lines
We reported the transcriptional effects of gemcitabine, genistein and the combined gemcitaibe/gensit...
GSE92967: Inflammatory Memory in Epidermal Stem Cells Accelerates Tissue Damage Responses
The bodys first line of defense against environmental assaults, the skins barrier, is maintained by ...
GSE97568: Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the mouse brain
The study provides new insights into how 5mC/5hmC vary across different part of brain, and the assoc...
GSE95750: Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq]
Nasopharyngeal carcinoma (NPC) is an invasive cancer with particularly high incidence in Southeast ...
GSE100484: mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells
Next Generation Sequencing Facilitates Quantitative Analysis of HL-60 cells transduced with control ...
GSE97090: RNA sequencing of Dorsal Root Ganglia upon axonal injury, in presence or absence of NAC (N-acetyl cysteine), and upon H2O2 nerve treatment
Purpose: A) compare the response to an axonal injury in the peripheral vs central nervous system B) ...
GSE88791: Two MicroRNAs and NF-kB Act in a Unique Regulatory Network to Ensure Precision of the Acute Inflammatory Response in Macrophages
The innate inflammatory response must be tightly regulated to ensure effective immune protection whi...
GSE105043: IL-1R8 is a checkpoint in NK cells regulating anti-tumor and anti-viral activity
We reported that IL-1R8 serves as a checkpoint for NK cell maturation and effector functions. Its ge...
GSE81193: Characterising the transcriptional profile of murine 3T3-L1 adipocytes with altered expression of IRF3.
The chronic inflammatory state that accompanies obesity is a major contributor to insulin resistance...
GSE120280: The IL-33/ST2 Axis Contributes to the Accumulation of Tumor-Infiltrating Regulatory T Cells
The objective of this study is to compare transcriptional features in tumor-infiltrating (TI) regula...
GSE88829: CTCF translates IL-2- and KG-sensitive metabolic changes in T cells into context-dependent differentiation gene programs [RNA-Seq]
We found that aspects of the IL-2-sensitive effector gene program in CD4+ Th1 and CD8+ Tc1 cells are...
GSE95519: Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Mouse siRNA]
To better understand transcriptional regulation during human oogenesis and pre-implantation embryoni...
GSE87561: Gene expression profile analysis of CD8+ T cells isolated from splenic red and white pulp upon LCMV infection
We performed RNAseq analysis on CD8+ T cells isolated from splenic white and red pulp upon lymphocyt...
GSE89885: Transcriptional profiling reveals gene programs that are differentially regulated in cardiac fibroblasts during exercise and disease
Purpose: Cardiac fibroblasts (CFs) contribute to pathological remodeling by proliferating and secret...
GSE88942: RNA-Seq from early time points in the kidney differentiation protocol
The kidney differentiation protocol takes induced pluripotent stem cells through to kidney organoid ...
GSE108770: Hypoxia-induced priming of microglial inflammatory gene expression is associated with TLR4 signaling H3K4me3 enrichment
We analyzed genome-wide H3K4me3 enichment and performed RNAseq analyses in N9 microglia cells after ...
GSE95477: Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age
Study Question: What effects do maternal age and oocyte maturation stage have on the human oocyte tr...
GSE115122: POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer [RNA-seq]
Transcriptome analysis by high throughput sequencing SOURCE: Olaf Klingbeil (klingbe@cshl.edu) - Co...
GSE87837: RNA sequencing on uninjured and injured cardiac regions of B6 and C3H strains
Purpose: To analyze gene expression in calcific (C3H) and non-calcific (B6) hearts; Methods: B6 and ...
GSE95587: Heterogeneity in neurodegenerative disease
RNA was purified from fusiform gyrus tissue sections of autopsy-confirmed Alzheimer's cases and neur...
GSE89326: Divergent expression patterns and regulation of the H3.3-encoding genes during normal development and carcinogenesis
Minor histone variants replace canonical histones in replication-independent manner, altering chroma...
GSE89152: Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression.
EMT, Epithelial to mesenchymal transition is a developmental biology process associated with migrati...
GSE90116: Transcriptomes of enriched mouse islet alpha cells
Glucagon supports glucose homeostasis by stimulating; hepatic gluconeogenesis, in part by promoting ...
GSE97324: RNA-seq analysis of MCT8-deficient and healthy control brain microvascular endothelial cells (BMECs) and neural cells
MCT8-deficient, healthy control and mutated/corrected isogenic iPSCs were differentiated into brain ...
GSE124209: Autophagic turnover of NBR1 restricts metastatic colonization during mammary tumor progression
Autophagy is implicated in promoting the metastatic potential of tumor cells. Utilizing a mouse mode...