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Sequencing-based assays page 15
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GSE87685: Next-gen RNA sequencing of mouse osteosarcoma tumors
Trascriptome analysis of osteosarcoma samples were performed SOURCE: Nuri,Alpay,Temiz University of ...
GSE89171: RNA-sequencing profiles of e12.5 transcriptomes in WT and Itgb1-/- mouse pituitaries.
The goal of the study was to understand how integrin beta1 expressed in epithelial cells directs dev...
GSE98734: A practical solution for preserving single cells for RNA sequencing
We present a method for histological tissue fixation using dithio-bis(succinimidyl propionate) (DSP)...
GSE90148: Transmural pressure is a master regulator of airway branching morphogenesis
Mechanical forces are increasingly recognized to regulate morphogenesis, but how this is accomplishe...
GSE94743: Insights into gene expression profiles induced by Socs3 depletion in Keratinocytes
Specific deletion of suppressor of cytokine signaling 3 (Socs3) in keratinocytes can cause severe sk...
GSE89364: The effects of Mycobacterium avium infection on hematopoietic stem cells
To investigate the changes in global transcriptome expression of HSCs following infection, we perfor...
GSE95771: AG221 and Ruxolitinib Treatment Effects on LSKs in IDH2-R140Q JAK2-V617F Transplant Recipients
Transplant recipients of IDH2-R140Q JAK2-V617F expressing bone marrow were treated with AG221 and ru...
GSE81316: Transgenic Expression Of Mitochondrial Chaperone Trap1 Accelerates Prostate Cancer Development
Protein homeostasis, or proteostasis is critical for organelle function, including mitochondria, but...
GSE95860: Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk.
We isolated the tip and stalk progenitors from four individual human embryonic lungs and used mRNAse...
GSE94950: Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa
Poly(A)-ClickSeq is a new methodology for the sequencing of the 3'UTR/poly(A) tail junction of RNA. ...
GSE109827: Gut Microbiota from Human Autism Spectrum Disorder Induces Behavioral Deficits in Mice
We transplanted gut microbiota via fecal transfer from TD and ASD children into germ-free wild-type ...
GSE105169: DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [ChrRNA-seq]
DHX36 is a ATP-dependent, 3-5 RNA helicase of the DEAH family. Previous publications reported this h...
GSE89182: MRTF activates TEAD-YAP target gene expression
Yes Associated Protein (YAP) and Myocardin Related Transcription Factor (MRTF) play similar roles an...
GSE89367: DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq1]
The cellular response to genotoxic stress is mediated by a well-characterized network of DNA surveil...
GSE89184: Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen
The inducible innate immune response to infection requires a concerted process of gene expression th...
GSE89412: B cell differentiation is limited by de novo DNA methylation [RNA-seq]
B cells provide humoral immunity by differentiating into antibody-secreting plasma cells, a process ...
GSE83351: Rapid Genome-wide Recruitment of RNA Polymerase II Drives Transcription, Splicing and Translation Events during T Cell Responses
Activation of immune cells results in rapid functional changes, but how such fast changes are accomp...
GSE94453: MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C]
In acute myeloid leukemia, chemotherapy resistance remains prevalent and poorly understood. Using fu...
GSE89196: Analysis of genes differencially expressed depending on Myc expression
The goal is to examine the transcriptome of ESCs with different Myc levels SOURCE: Fatima Sanchez-Ca...
GSE89460: Activity-dependent gene expression in the mammalian olfactory epithelium
We access the activity-dependent genes in olfactory neuron cells with unilateral naris occlusion mod...
GSE106521: Gene Expression Changes in the LA/BC muscle of a knock-in mouse model of SBMA
Examining changes in expression in a mouse model of SBMA compared to WT littermates. SOURCE: Richard...
GSE90097: RNA-Seq Analysis of Dose-Dependent TCDD-Elicited Jejunal Gene Expression in Male Mice
Dose-dependent jejunal gene expression was examined following repeated exposure (every 4 days for 28...
GSE94991: Dynamic control of translation during adult neurogenesis
Here we applied RNAseq and RIBOseq, the deep sequencing of ribosome-associated transcripts, to inves...
GSE95176: GCTM-5 positive and negative cells in pancreatic adenocarcinoma cell lines
Analysis of GCTM-5 positive and negative cells sorted from CFPAC-1 and SW1990 human pancreatic adeno...
GSE97375: Prostaglandin E2 is required for skeletal muscle stem cell function, augmenting regeneration and strength
To identify the downstream signaling pathways that contribute to expansion of MuSCs by PGE2 SOURCE: ...
GSE129449: Transcriptomic profiling of MLL-r AML PDX cells treated with CDKI-73 and/or JQ1
Transcriptomic profiling of MLL-r AML PDX cells treated with CDKI-73 and/or JQ1 SOURCE: Richard D'An...
GSE96738: Transcriptional profile of homozygous inactivation of Nf1 in mature oligodendrocytes
White matter abnormalities have been observed in Neurofiromatosis type 1 (NF1) patients and in mouse...
GSE95853: Metallothionein I as a direct link between therapeutic hematopoietic stem/progenitor cells and cerebral protection in stroke
Background: Increasing evidence indicates stem cell transplantation may be an effective stroke treat...
GSE98805: RNA-seq of head and neck cancer cell lines
Transcriptome analysis in head and neck cancer cell lines, FaDu and UMSCC47 with and without 5-aza'...
GSE89895: Impact of regulatory variation across human iPSCs and differentiated cells
Induced pluripotent stem cells (iPSCs) are an essential tool for studying cellular differentiation a...
GSE112244: Th1 and T17 activation with and without CB839 treatment
Activated T cells differentiate into functional subsets which require distinct metabolic programs. G...
GSE90469: Ribosome profiling experiments of G2019S LRRK2 human dopamine neurons
G2019S mutation of LRRK2 is known to increase mRNA translation. We perform ribosome profiling to stu...
GSE89485: Therapeutic targeting MLL degradation pathways in MLL-rearranged leukemia
Chromosomal translocations of the mixed-lineage leukemia (MLL) gene with various partner genes resul...
GSE96779: mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment
To establish effective multitargeted KRAS pathway therapy, we analyzed mediators of acquired resista...
GSE150967: Mammary gland tumor immunoinfiltrate analysis
In this experiment we compare the gene expression profile using two different models of mammary glan...
GSE86479: Pseudotemporal ordering of single cells reveals metabolic control of postnatal beta cell proliferation
Maintenance of blood glucose homeostasis depends on appropriate pancreatic beta cell mass, which is ...
GSE96783: Allergen-induced activation of NK cell genes represents an early life immune response in development of allergic asthma
Peripheral blood samples from children enrolled in the URECA cohort were collected at age 2. In shor...
GSE96724: T-bet regulates how T helper 1 cells interpret IFN- signals
Host defense requires the specification of CD4+ helper T (Th) cells into distinct fates including Th...
GSE84832: KRAB-ZFP/KAP1 is essential to restrict excessive IGF2 expression during mouse embryo development
Insulin-like growth factor 2 (Igf2) is the major fetal growth hormone in mammals. Here we identify t...
GSE115182: Gene expression signatures in IL27RA- and IL27RA+ hematopoietic stem cell
Analysis of IL27RA- and IL27RA+ hematopoietic stem cell (lineage-, c-kit+ Sca-1+ CD150+, CD34-). The...
GSE97762: A context-specific cardiac Beta-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart [RNA-eq]
Summary: Activation of the evolutionarily conserved, developmental Wnt pathway has been reported dur...
GSE89415 (human): RNA-seq analysis of EZH1 knockdown in 5F cells, or EZH1 heterozygous and homozygous knockout YS and AGM cells
Blood develops in distinct stages. Haematopoietic progenitors in the embryo manifest restricted diff...
GSE88819: Deletion of the Tug1 locus leads to male sterility and affects gene expression in multiple tissues
We have sequenced wild type and mutant testes, prostate, liver, heart, spleen, and eye from adult ma...
GSE89569: RNAseq analysis of NR0B1 LOF
We report analysis of transcriptional chanages following RNAi depletion of NR0B1 or NRF2 depletion i...
GSE89198: BCL11B AND COMBINATORIAL RESOLUTION OF CELL FATE IN THE T-CELL GENE REGULATORY NETWORK
We report the RNA-seq results from mouse T-cell precursors in different developmental stages includi...
GSE98197: Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis
Our mouse model (Ksp-CreER/Sav1fl/fl ) offers novel insights into molecular events that are linked t...
GSE112166: STAT5 activation enhances Paneth cell function by regulated ileal Wnt3a-Tcf4-Sox9 or Gfi1 to sustain niche differentiation.
To determine the potential molecular mechanisms by which STAT5 signaling control ileal Paneth cell h...
GSE115206: Genome wide analysis of SAHA (vorinostat) treatment in primary mouse cortical neurons upon miR-203 overexpression
Purpose: The goal of this study was to assess gene expression changes upon SAHA treatment in cells o...
GSE89134: Hit-and-run' programing of CAR-T cells using mRNA nanocarriers
RNAseq of ex vivo CD8 T cell lineages and in vitro differentiated CD8 T cells treated with nanocarri...
GSE106388: Enhanced interferon response genes in bronchial epithelial cells after in vivo rhinovirus challenge of asthma patients
In asthma there are exaggerated rather than impaired innate and adaptive interferon responses in viv...
GSE89619: Genome-wide analysis of transcription in in vitro- and in vivo-derived motor neurons
RNA sequencing analysis of Hb9::GFP mouse embryonic fibroblasts, Hb9::GFP+ primary mouse embryonic m...
GSE96055: Time-course analysis of microglia-specific RNA-seq in two severities of spinal cord injury
RNA-seq analysis of microglia following spinal cord injury demonstrated that microglia response is d...
GSE83940: Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPAR2
The pathophysiologic continuum of non-alcoholic fatty liver disease begins with steatosis. Despite g...
GSE96885: CD14+ IMC treated TGF-beta
CD14+ human immature myeloid cells were treated with TGF-beta for increased periods of time to study...
GSE104553: Whole transcriptome analysis of T11 treated with FPP-1746-Omomyc
RNA Sequencing of claudin-low triple negative breast cancer cells T11 treated with FPP-1746-Omomyc, ...
GSE98841: Overlap in Signaling through Smoothened and the Heterotrimeric G Protein G13
RNA sequencing is used to compare genes regulated by a constitutively active form of Smoothened, a p...
GSE98101: Spatial-temporal epigenetic landscape of mouse gastrula
Regionalized lineage progenitor cells emerged from the onset of gastrulation would facilitate mouse ...
GSE106210: Transcriptomic response to adult hypothalamic deletion of Snord116
Snord116 deletion mouse models recapitulate aspects of the Prader-Willi Syndrome. In this study, we...
GSE87365: ERBB3 and NGFR mark distinct skeletal muscle progenitor cells in human development enabling enrichment and maturation of hPSC muscle
Abstract: Human pluripotent stem cells (hPSCs) can be directed to differentiate into skeletal muscle...
GSE97165: RNAseq study of synovial biopsies after triple DMARD treatment
Total RNA sequencing was performed on samples isolated from joint synovial biopsies from subjects wi...
GSE92618: Comparative genomic analysis of basal and LPS-induced expression patterns of bone marrow derived macrophages and bone marrow resident macrophages
Comparative genomic analysis of basal and LPS-induced expression patterns of bone marrow derived mac...
GSE109416: Analysis of differential gene expression in the striatum of R6/2 Huntington's disease model vs. control mice
5 mice per group of each: R6/2 and isogenic wild-type controls. SOURCE: Myriam Heiman (mheiman@mit.e...
GSE106510: T helper cells modulate intestinal stem cell renewal and differentiation
Using single-cell RNA-seq of intestinal epithelial cells we identify surprising expression of MHC cl...
GSE83373: The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons
Purpose: To assess changes in gene expression profiles from the P0 littermate Sp9Flox/Flox control s...
GSE103866: Single cell analysis reveals cancer cell heterogeneities in hepatocellular carcinoma [SMART-seq]
Combined transcriptomic and functional analyses of HCC cells at single-cell level were performed to ...
GSE96962: Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells
Smooth muscle cells (SMCs) and endothelial cells (ECs) constitute vasculature media and endothelium,...
GSE99440: Reduced circulating insulin enhances insulin sensitivity in old mice and extends lifespan
The causal relationships between insulin levels, insulin resistance, and longevity are not fully elu...
GSE111136: scRNAseq of aging dermal fibroblasts
Transcriptomic analysis of murine aging dermal fibroblasts at single cell level. SOURCE: Gustavo Rod...
GSE157391: Gene expression profiles of in vitro CD105pos and CD105neg pancreatic fibroblasts (PaFs) after stimulation with various recombinant proteins
CD105pos and CD105neg PaFs were isolated from B6 murine pancreas, subjected to in vitro stimulation ...
GSE88970: Next Generation Sequencing Comparison of Wild Type and Whsc1-/- BM sorted proB Cell Transcriptomes
Whsc1 gene codes for a SET domain-containing H3K36 dimethylase, whose activity has been suggested, i...
GSE96931: RNA sequencing of lncRNAs knockdown in human pancreatic cancer cell lines
We report the transcriptome changes that result from the transient knockdown of FAM83H-AS1 in Aspc1 ...
GSE114424: Asf1a resolves bivalent chromatin domains for the induction of lineage-specific genes during mouse embryonic stem cell differentiation
Bivalent chromatin domains containing both repressive H3K27me3 and active H3K4me3 modifications are ...
GSE129520: A novel leiomyoma genetic mouse model
We report the RNAseq data from uterine tissues obtained from mice that over-express KRAS-G12D or KRA...
GSE108995: Profiling of escape kinetics of viruses subjected to RNAi
To assess how viruses of different genome compositions escape engineered RNAi SOURCE: Benjamin tenOe...
GSE98487: The GNAS-R201C Mutation Associated with Clonal Hematopoiesis Maintains Mouse Long-Term Hematopoietic Stem Cell Potential
Gene expression analysis of mouse hematopoietic stem cells (HSCs) transduced with lentiviral vectors...
GSE92721: Transdifferentiation as a mechanism of treatment resistance in a mouse model of castration-resistant prostate cancer
Analysis of transcriptome of prostate tissue from the anterior lobe or tumor from 9, 12, 13, 14, and...
GSE94724: Transcriptome analysis of HCMV infected tissues
We report the application of RNA sequencing for transcriptome analysis of HCMV infected tissues, ena...
GSE118248: Loss of CBP in newborn neurons interferes with synaptic maturation and SRF-dependent neuronal growth
We used genome-wide sequencing methods to study the consequences of eliminating the CREB-binding pro...
GSE92983: Reprogramming methods influence DNA methylation and expression patterns of mouse induced pluripotent stem cells [RNA-seq]
Induced pluripotent stem cells (iPSCs) can be derived from somatic cells through ectopic expression ...
GSE92361: The impact of Tcf1/Lef1 deficiency and prostagladin E (PGE) treatment on leukemic stem cell (LSC) transcriptome
Comparison of trasncriptome bewteen control LSCs and Tcf1/Lef1 deficient LSCs, LSCs treated with DMS...
GSE90153: Colon lamina propria myeloid cell subpopulations versus intratumoral counterparts
Monocytes, neutrophils and tissue resident macropahges of colon lamina propia are compared to their ...
GSE106294: Role of GDF10 for axonal sprouting and functional recovery after stroke
GDF10 controls a unique transcriptome, which coordinately regulates several molecular signaling syst...
GSE98507: CTCF depletion effect in B cells
Role of CTCF in activated B cells. SOURCE: Manuel,J,Gomez (mjgomezr@cnic.es) - Bioinformatics Unit C...
GSE108532: Effect of ablation of the alternative NF-kB pathway on the regulatory T cell (Treg) transcriptome
We report here the transcriptome analysis of in-vitro stimulated WT, nfkb2-/-, Relb-/- and nfkb2-/-R...
GSE98768: Histone H3.1K27 methylation promotes NHEJ by antagonizing FANCD2 on Chromatin
The goals of this project are to study the transcriptome profiling (RNA-seq) of human fribroblast ce...
GSE106526: High-throughput RNA seq data of mouse embryonic stem cells and intermediate states throughout their differentiation into motor neurons
Piezo1 is a mechanosensitive (MS) ion channel with characteristic fast-inactivation kinetics express...
GSE100417: Global transcriptome analysis of WT versus HEB-/- hESCs
To examine genome-wide changes in mRNA expression, we performed RNA-Seq on HEB-/- and WT hESCs. Ther...
GSE106844: Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma
By genome-wide ChIP-seq analysis in ABC DLBCL cell lines, we identified 2,251 STAT3 direct target ge...
GSE92626: Identification of genes induced by NOTCH1 in a chronic lymphocytic leukaemia (CLL) cell line and tracking of these genes in primary CLL patients
NOTCH1 is mutationally activated in ~15% of cases of chronic lymphocytic leukaemia (CLL), but its ro...
GSE94556: LSD1/KDM1A Maintains Genome-wide Homeostasis of Transcriptional Enhancers [RNA-Seq]
We performed sequencing of Nuclear RNA from Lsd1-WT, Lsd1-GT, KDM5c-WT, and KDM5C-KO mouse embryonic...
GSE93292: Gene expression changes after LOC550643 silencing
Differential analysis of gene expression in HEK293T cells treated with a pool of siRNA targeting LOC...
GSE89225: Regulatory T cells exhibit distinct features in human breast cancer
The goal of this study is to compare transcriptional profiles of regulatory T cells and conventional...
GSE98822: Constitutive and Tamoxifen inducible knockout of HDAC1 and HDAC2 in Microglia
Hdac1 and 2 are important regulators of developmental processes. In this study we created microglia ...
GSE93706: OCT6 uniquely replaces OCT4 in inducing human pluripotency
Somatic cells can be reprogrammed into pluripotent stem cells by the ectopic expression of OCT4, SOX...
GSE90459: RNA-seq analysis of mouse brain endothelial cells and glioma endothelial cells
Glioblastoma multiforme (GBM) is a highly aggressive and vascularized malignant brain tumor. Anti-VE...
GSE103850: 5hmC and gene expression data in breast cancer cell lines treated with an antioxidant
In this study, we identify genes with enriched 5-hydroxymethyl-cytosine (5hmC) modifications correla...
GSE109843: A novel CD4+ T cell population expanded in Systemic Lupus Erythematosus (SLE) blood provides B cell help through IL10 and succinate
A better understanding of the molecular and cellular factors involved in human plasma cell different...
GSE102512: Transcriptome profiling of in vitro cellular entities involved in lung tumour fusion events
Cell fusion theory for explaining metastasis origin has been hypothesised for almost one-hundred yea...
GSE92634: RNA sequencing of Epiblast stem cells, nodal inhibited epiblast stem cells and embryonic samples
To characterize the molecular properties of the EpiSCsS/F, we compared the transcriptome of EpiSCsS/...
GSE102230: mRNA-Seq profiling SIX2+ and Foxd1+ cells in mouse embryonic and SIX2+ and SIX2-/MEIS1+ cells human fetal kidney
To characterize the molecular features of human and mouse nephron progenitors and stromal cells we p...