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Sequencing-based assays page 18
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GSE93514: MACROD2 haploinsufficiency promotes chromosome instability and growth of intestinal tumors
RNA-Seq data from intestinal tumors of ApcMin/+/Macrod2-/-,ApcMin/+/Macrod2-/+ and ApcMin/+/Macrod2+...
GSE101923: Gene expression profile of multiple myeloma cell lines treated with CB-5083
The goal was to determine the gene expression differences between CB-5083 and Bortezomib treated mul...
GSE107495: Expression profiling of mouse eosinophils and myeloid progenitors
We have sequenced using single end and paired end sequencing GMPs, CMPs, EoPs, SiglecF+IL5ra- GMPs a...
GSE107121: Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor)
Mammary epithelial cells were treated with control or BRCA2 siRNAs, then allowed to recover for 4 pa...
GSE93412: Comparison of translational profiles in Motor Neurons (CHAT), to all neurons (Snap25) in the spinal cord.
Translating ribosome affinity purification (TRAP) was performed on spinal cord dissections pooled fr...
GSE85385: EZH2 is a potential therapeutic target for H3K27M mutant paediatric gliomas [RNA-Seq - mouse cell lines]
Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive brain tumour that is located in the p...
GSE93511: A genome-wide analysis of human pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels compared to standard 2D or 3D cell culture platforms
The influence of 2D and 3D cell culture platforms on vascular function was investigated by comparing...
GSE93097: Loss of a CDR1as, a conserved mammalian circRNA, causes miRNA de-regulation and a psychiatric phenotype [RNA-seq]
Circular RNAs (circRNAs) are highly expressed in mammalian brains, with oftentimes conserved express...
GSE101531: RNA seq analysis of human Fetal and adult derived Enterospheres
enterospheres (FEnS) from six aborted fetal small intestines, ranging in gestational age from 11 to ...
GSE93624: Profiling of Ileal Transcriptome in Pediatric Crohn Disease
We report ileal gene expression at diagnosis in a cohort of 210 treatment-nave patients of pediatric...
GSE104086: RNAseq data on HDAC Class IIa inhibitor (CHDI-00390576) dosed R6/2 mice.
R6/2 and WT mice treated orally twice a day with vehicle (10% HPCD), and R6/2 mice treated with eith...
GSE95122: Priming and Activation of ER Enhancers Through Ordered and Cooperative Interactions Between p300 and Mediator [GRO-seq]
Estrogen receptors alpha (ER) converges estrogen signaling by orchestrating estrogen (E2)-dependent ...
GSE106694: GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 2)
The estrogen receptor (ER) is expressed in the majority of luminal breast cancers and inhibition of ...
GSE106669: Repression of Human and Mouse Brain Inflammaging Transcriptome by Broad Gene Body Histone Hyperacetylation (RNA-seq)
RNA-seq data of human prefrontal cortex and mouse brain during aging and/or SAHA treatment were gene...
GSE108750: RNA-seq of Egr1-/- and Tet1-/- mouse frontal cortex
We performed transcriptome profiling for frontal cortex tissues derived from 6~8 week old Egr1-/- an...
GSE83134: RBYP stimulates PRC1 to shape chromatin-based communication between polycomb repressive complexes [RNA-seq]
Polycomb Repressive Complexes (PRC), and their chromatin-modifying activities, are essential for the...
GSE93314: Cell cycle dynamics and complement expression distinguishes mature hematopoietic subsets arising from hemogenic endothelium
We report the transcriptional profiling of intra-aortic clusters (IAHCs) at different time points of...
GSE134522: EMP2 functions as a novel target for breast cancer stem cells
Little is know about the role of epithelial membrane protein-2 in breast cancer development or progr...
GSE94832: HDAC3-mediated regulation of the circadian gene Per1 contributes to age-related impairments in hippocampal memory and synaptic plasticity
We performed an RNA Sequencing experiment on dorsal hippocampal tissue from six groups of animals: A...
GSE119513: Comparison of Transcriptomes between A549 and H23 Cells
We profiled transcriptomes in human lung cancer cell lines H23 and A549 cells. SOURCE: Bin Shan (bin...
GSE102857: A molecular roadmap of the aorta-gonad-mesonephros region reveals BMPER as a novel regulator of HSC maturation [AGM]
In the developing embryo, haematopoietic stem cells (HSCs) emerge from the aorta-gonad-mesonephros (...
GSE96093: RNA-sequencing of hepatocyte specific ABCA1 deletion mice
ATP binding cassette transporter A1 (ABCA1) regulates cellular cholesterol efflux. We characterized ...
GSE94072: Subepithelial telocytes are an indispensable source of Wnt ligands supporting intestinal crypts
We successfully sequenced and annotated Foxl1 positive and Foxl1 negative mouse intestine mesenchyma...
GSE92751: Inhibition of Ubc13-mediated ubiquitination by GPS2 regulates multiple stages of B cell development
Non-proteolytic ubiquitin signaling mediated by K63 ubiquitin chains plays a critical role in multip...
GSE95156: Pancreatic alpha and beta-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression
We performed a parallel analysis of the molecular properties of - and -cell oscillators, using a mou...
GSE107574: The human blood-nerve barrier transcriptome
We report the application of whole exome sequencing to comprehensively deduce the normally conserved...
GSE103528: CARM1/PRMT4 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis
We investigated the role of PRMT4 in normal and malignant hematopoiesis.; We found that knockdown of...
GSE103548: Analysis of mRNA Expression in Lewis Lung Carcinoma (LLC1) Cells and MLE 12 cells
Whole transcriptome sequencing was used to analyze mRNAs expressed by LLC1 and MLE 12 cells. SOURCE:...
GSE95638: RNAseq Analysis of Transcriptome expression profiles in E12.5 and E13.5 FACS sorted Osr2RFP/- (mutant)and Osr2RFP/+ (control) palatal mesenchymal cells
Purpose: The purpose of this study is to compare the transcriptome expression profiles of E12.5 and...
GSE93620: Gene expression in HT-29-MTX intestinal epithelial cells treated with Ancylostoma ceylanicum hookworm larvae
HT-29-MTX cells were treated with Ancylostoma ceylanicum hookworm larvae or left untreated. The dif...
GSE103489: T cell activation in skin explants from patients with psoriasis and controls
We have worked on skin explants and activated T cells locally with a CD3 antibody, whole biopsies we...
GSE89900: Transcriptional dynamics of paternal X chromosome reveals different epigenetic memory of the inactive state in the inner cell mass
This study concerns the dynamics of reprogramming of the inactive X chromosome in the inner cell mas...
GSE106147: Identify the master regulator of ILT3.Fc induced perturbation in Jurkat cells
Generate gene expression profile of ILT3.Fc treated Jurkat cells SOURCE: Zheng Xu (xuzhenghzau@gmail...
GSE98866: Gene expression changes upon drug withdrawal (A375/451Lu cell lines)
In this study we investigate the mechanism of drug addiction SOURCE: Oscar Krijgsman (o.krijgsman@nk...
GSE102675: RNAseq in C57Bl6 and congenic Atf3-/- mice
RNA expression from whole pancreatic tissue was assessed by RNA-seq following 4 hours into cerulein-...
GSE117608: Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell
In response to blood vessel wall injury, aberrant proliferation of vascular smooth muscle cells caus...
GSE113035: Seletive inhibition of CDK9 in DLBCL cell lines
Deregulation of the MYC transcription factor is a key driver in lymphomagenesis. MYC induces global ...
GSE107578: Fine-tuning Mybl2 levels are required for proper MET process during somatic reprogramming [RNA-seq]
Genome wide data investigating the role of Mybl2 in reprogramming SOURCE: Carl Ward (crjward@gmail.c...
GSE107787: Fasting Imparts a Switch to Alternative Circadian Transcriptional Pathways in Liver and Muscle
The circadian gene expression in peripheral tissue displays rhythmicity which is driven by the circa...
GSE100873: Mouse macropahge RNA-seq with or without virus infection
To investigate the role of lncRNAs in viral infection and their relationship with the IFN-I system, ...
GSE100881: Analysis of RNA-seq libraries for conditional knock-out of transcription factors in adult mouse pancreas
The purpose of this study is to determine the roles and hierarchy of the transcription factors Foxa2...
GSE93180: Tau-P301S sorted cell types
Mice of indicated sexes and genotypes were perfused and their brains dissected and dissociated. Cell...
GSE105089: Lung Epithelial Response to Cigarette Smoke and Modulation by the Nicotinic Alpha 7 Receptor
We report the impact of side-stream cigarette smoking on baseline tracriptional status of enriched e...
GSE98988: Histone H3K4 methylation-dependent and independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation
Of the six members of the COMPASS (complex of proteins associated with Set1) family of histone H3 Ly...
GSE121489: Transcriptomics analysis of enteroendocrine cells after vertical sleeve gastrectomy
We report here the transcriptome of sorted enteroendocrine cells from duodenum, ileum and colon from...
GSE121120: RNAseq analysis on E14.5 midbrain material from mouse, Lmx1b fl/fl; Pitx3-Cre vs Lmx1v wt/wt;Pitx3-Cre littermates
Lmx1b influences the subsets specification in midrbain DA neurons SOURCE: Marten,Piet,Smidt (smidt.m...
GSE87453: Epistasis between TIFAB and miR-146a, neighboring genes in del(5q) MDS
Interstitial deletion of a single copy of chromosome 5q is the most frequent cytogenetic alteration ...
GSE93380: Gene expression profiling of Male and Female adult mouse liver using RNA-seq
RNA-seq analysis of intact male and female adult mouse liver SOURCE: David,J.,Waxman (djw@bu.edu) - ...
GSE94849: RNA Sequencing of Pinometostat Sensitive and Resistant Paired Cell Lines
MLL-r cell lines KOPN-8 and NOMO-1 were cultured with pinometostat to derive treatment emergent resi...
GSE110188: Neuro-glial crosstalk regulates microglia activation and control of viral encephalitis
In this study it was possible to compare the behaviour of different myeloid cell populations upon VS...
GSE104310: Gene Expression Profile of human hepatocellular carcinoma by RNA sequencing
The aim of the present study was to investigate biomarkers in the malignant process of HCC by high t...
GSE104161: Gene expression profiles of SIRT6-deficient pancreatic beta cells from Ngn3-Cre Sirt6 f/f and MIP1-CreERT Sirt6 f/f mice
Purpose: The complete understanding of how genetic and epigenetic components control beta cell diffe...
GSE103667: Transcriptome-wide profiling of translation efficiency using mRNA-seq and Ribo-seq in ER stress-induced NIH3T3 cells
We report systematical profiling of translation efficiency in stress conditions of NIH3T3 cells. SOU...
GSE107894: Metformin Regulates Metabolic and Non-Metabolic Pathways in Skeletal Muscle and Subcutaneous Adipose Tissues of Older Adults
Administration of metformin increases healthspan and lifespan in model systems and evidence from cli...
GSE98898: A prostate cancer risk element functions as a repressive loop that regulates HOXA13
Prostate cancer (PCa) is the leading cancer among men in the United States, with genetic factors con...
GSE107050: Biomodal role of H3.3 in safe-guarding and establishing cell identities during reprogramming [RNA-Seq H3.3 KD]
Determination of transcriptome rewiring during cellular reprogramming in cells in which H3.3 had bee...
GSE98133: Determination of Lsd1 function in C2C12 myoblast cells by global transcriptome analysis
First, we aimed to identify genes whose transcript levels change at the onset of myogenic versus adi...
GSE93085: Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells
Examine differences in Type-1 alveolar epithelial cells with and without alveolar macrophages during...
GSE104581: Beta cell-targeted glucokinase overexpression
RNA sequecing of isolated mouse islets from C57BL/6J mice fed high fat diet following control or AAV...
GSE103670: Angiogenic factor imbalance precedes complement deposition in the placenta of preeclamptic-like BPH/5 mice
BPH/5 mice are an inbred strain with borderline hypertension that spontaneously develops both matern...
GSE112401: Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor and estrogen receptor signalling pathways in endocrine resistant breast cancer
Our data supports the potential combination of inhibition of ERBB2/3 signalling with mTORC1 perturba...
GSE116146: Gene expression of subtypes of neocortical projection neurons over developmental time is correlated with cell class-specific chromatin accessibility
Excitatory projection neurons of the neocortex can be classified as occupying the upper layers, laye...
GSE104797: Protein kinase D1 deletion in adipocytes enhances energy dissipation and protects against adiposity
DAG-activated Pkd1 promotes triglyceride accumulation in adipocytes; Pkd1 promotes lipogenesis and s...
GSE107593: UC Colon RNAseq subset analysis
RNAseq was used to confirm findings from microarrays and identify additional genes different between...
GSE89415 (mouse): RNA-seq analysis of EZH1 knockdown in 5F cells, or EZH1 heterozygous and homozygous knockout YS and AGM cells
Blood develops in distinct stages. Haematopoietic progenitors in the embryo manifest restricted diff...
GSE98168: Macrophage function in tissue repair and remodeling requires IL-4/IL-13 with apoptotic cells [Run2]
Tissue repair is a subset of a broad repertoire of IL-4/IL-13-dependent host responses during helmin...
GSE108807: Transcriptome Profiling of Neutrophils from Patients Infected with IAV using RNA-seq
Purpose: To explore the roles of host lncRNAs during IAV infection; Methods:profiling whole transcri...
GSE97113: Sex-biased hippocampal pathology in the 5XFAD mouse model of Alzheimer's disease: A multi-omic analysis
Numerous neurological disorders, including Alzheimer's disease, display a sex-biased prevalence. To ...
GSE104036: AGO CLIP reveals an activated network for acute regulation of brain glutamate homeostasis in ischemic stroke [dataset 2]
Adult mouse cortical tissues after MCAO or sham surgery were analyzed by RNAseq at various time poin...
GSE94859: EOMES-expressing CD4+ T cells are increased in PTPN22 (1858T) risk allele carriers
The presence of the PTPN22 risk variant (1858T) is associated to several autoimmune diseases includi...
GSE92844: Gene expression profiling of mouse brown and white adipose tissues
Gene expression profiling of supraclavicular brown, interscapular brown, inguinal white, and epididy...
GSE98584: Gene expression profiling of continuous growth hormone infused (cGH) adult male mouse liver by RNA-seq analysis of polyA-selected liver RNA. [G88_G96]
PolyA-selected RNA isolated from livers of adult male mice treated with a continuous infusion of gro...
GSE108833: Regulation of hypoxia-inducible factor activity by ZMYND8
ZMYND8 coactivates the global HIF target genes in breast cancer MDA-MB-231 cells. SOURCE: Weibo Luo ...
GSE109793: LSK cells transfected with Hhex retrovirus
The Hematopoietically-expressed homeobox (Hhex) transcription factor is overexpressed in human myelo...
GSE126662: Comparison between opioid (morphine) and vehicle treatments in mouse trigeminal ganglia and nucleus accumbens
Chronic opioid treatment elicits hyperalgesia in mice that is significantly augmented by a human mig...
GSE93327: Transcriptome profiles of seminiferous tubes on different stage of spermatogenesis
In order to get the different gene expression profiles of these seminiferous tubules on different st...
GSE94860: YAP/TAZ as new regulatory hub of VEGF signaling [RNA]
VEGF is a major driver of blood vessel formation.; However, the signal transduction pathways culmina...
GSE142589: m6A RNA methyltransferases Mettl3/14 regulate immune responses to anti-PD-1 therapy
We analyzed the RNA-seq and MeRIP-seq data from Mettl3/14 CRISPR knock-out and control CT26 colon ca...
GSE96541: Blockade of IFN-alpha by antibody or CYM-5442 reveals a unique transcriptional gene signature in autoimmune CD8+ T cells and pancreatic islets
Blockade of interferon (IFN)-alpha but not IFN-beta signaling using either an antibody or a selectiv...
GSE126660: Epidermal basal cell-specific in vivo ribosome profiling to describe the translation landscape of HrasG12V and Eif2b5
eIF2B5 is necessary for HrasG12V hyperplastic growth. Ribosome profiling was used to describe HrasG...
GSE100060: Adipocyte p62/SQSTM1 suppresses tumorigenesis through the opposite regulation of metabolism in fat and tumor
Obesity is a leading risk factor for tumorigenesis and there is emerging support for a positive asso...
GSE107615: Mutant IDH1 promotes glioma formation in vivo [RNA-seq]
RNA was isolated from FFPE samples of IDH1 mutant, WT tumors and normal brains SOURCE: Sheri Holmen ...
GSE105447: A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit
We profiled two IDH1 mutant glioma models, grown as intracranial xenografts, treated with an IDH1 in...
GSE138201: Altering sphingolipid metabolism attenuates cell death and inflammatory response after myocardial infarction
We performed transcriptomic analyses to evaluate changes in gene expression post MI. We investigated...
GSE113281: RNASeq: lenalidomide-treated anti-BCMA CAR T cells
Transcriptom-wide RNA expression profilng in human CAR-T cells treated with lenalidomide in the pres...
GSE111377: Unique features and clinical importance of acute alloreactive immune responses
By 2 weeks after stem cell transplantation, there was differentiated changes in T cell phenotype bet...
GSE109287: Expression data from bone marrow derived macrophages (BMDMs) in Wild Type and NICcA
The Notch pathway plays a critical role in regulating the development and polarization of macrophage...
GSE108854: Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential
Gene expression profiles from ALDH high cells sorted from expanded adult human pancreatic organoids ...
GSE111517: Snapshot of translation in mammalian cells that are depleted of polyamines or replete with polyamines
Snapshot of translation in mammalian cells that are depleted of polyamines or replete with polyamine...
GSE101868 (human): Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity
Despite increasing evidence to indicate that long non-coding RNAs (lncRNAs) are novel regulators of ...
GSE102160: Single cell RNA Seq data of BMDM from mouse infected with Salmonella [full time course]
The interaction between a pathogen and a host is a highly dynamic process in which both agents activ...
GSE105064: Transcriptomic insights into human decidual and peripheral blood CD8 T cells
We performed the analysis of transcriptional and alternative splicing landscapes for paired decidual...
GSE112402: Polycomb repressive complex 1 (PRC1) role in skin epithelium development [Epi Eed cKO]
Polycomb repressive complexes (PRC) 1 and 2 are essential chromatin regulators of cell identity. PRC...
GSE113065: Uterine glands synchronize embryo-endometrial interactions and coordinate on-time embryo implantation and stromal cell decidualization for pregnancy success
By employing FOXA2-deficient mouse models coupled with LIF repletion, we reveal definitive roles of ...
GSE84610 (mouse): CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair
BACKGROUND:; Deletion of the chromatin remodeler CHD1 is a common genomic alteration found in human ...
GSE93622: MLL2, but not MLL1, plays a major role to sustain leukemia survival [RNA-seq]
We investigated the effect of Mll1, Mll2 and Mll1;Mll2 deletion on gene expression in MLL-AF9-transf...
GSE105170: DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [cPDS-RNA-seq]
DHX36 is a ATP-dependent, 3-5 RNA helicase of the DEAH family. Previous publications reported this h...
GSE103044: Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes
Gene expression variation upon folate deficiency and repletion in human foreskin keratinocytes immor...
GSE101537: Neurog3-Cre p300/CBP mouse islets RNA-seq
We have performed RNA-seq on mouse islets lacking all p300 (p300 KO), all CBP (CBP-null), and one co...
GSE93543: Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4
Purpose: Identifying target genes of the two human chromatin remodeling enzymes CHD3 and CHD4; Metho...