Explore curated data sets and assays
Pluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for access
Sequencing-based assays page 27
Store large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
GSE52260: Comparative analysis of human and mouse transcriptomes of Th17 cell priming.
Uncontrolled Th17 cell activity is associated with cancer and autoimmune and inflammatory diseases. ...
GSE114824: Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides
A difference in the transcriptomes of 8F10 T cells sourced from the NOD (8F10-NOD) or B16A (8F10-B16...
GSE120805: RNA-Seq analysis of human lens epithelial cells exposed to ionizing radiation
Purpose: The International Commission on Radiological Protection (ICRP) recently recommended reducin...
GSE52656: Leucegene: AML sequencing (part 2)
RNA sequencing of human leukemia SOURCE: Guy Sauvageau Institute for Research in Immunology and Canc...
GSE57609: Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast
The pluripotent mammalian epiblast undergoes unusually fast cell proliferation. This rapid growth is...
GSE53538: The GYF domain protein CD2BP2 plays a crucial role in alternative splicing, embryonic development and podocyte integrity
The spliceosome is a multimolecular ribonucleoprotein complex, which catalyzes the removal of intron...
GSE120851: Liver lncRNA gene expression in response to CAR/PXR agonists
Gene expression in livers of male and female mice treated with the CAR agonist ligand TCPOBOP or the...
GSE54113: Genome wide analysis of the direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells
A dominant negative allele of TR1 (TRAMI) has been introduced only in Sertoli cells using the Cre/lx...
GSE56367: Jmjd3-mediated H3K27me3 dynamics orchestrate brown fat cell fate transition and regulate white fat plasticity (RNA-Seq)
We performed RNA-Seq for brwon fat, epididymal white fat and soleus muscle of mice to identify brown...
GSE54460: RNAseq Analysis of Formalin-Fixed Paraffin-Embedded Prostate Cancer Tissues
In an effort to identify biomarkers of recurrence, we have performed global RNA-sequencing on 106 fo...
GSE104985: KDM5B links cellular transcriptome heterogeneity to therapy resistance (RNA-Seq)
The KDM5B histone H3 lysine 4 (H3K4) demethylase has been implicated in therapy resistance in multip...
GSE50809: Temporally defined neocortical translation and polysome assembly is determined by the RNA-binding protein, Hu antigen R
Precise spatiotemporal control of mRNA translation machinery is essential to proper development of h...
GSE151936 (human): C9orf72 in myeloid cells suppresses STING-induced inflammation
In this study we report that loss of C9orf72 expression in myeloid cells drives STING/type I interfe...
GSE53470: ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration
Knockdowns of c-JUN and JUND had opposite effects on PC3 prostate cell migration. We predicted that ...
GSE53635: RNA-seq analysis of differentiating human erythroblasts
Human erythroblasts purified from cord blood were cultured in vitro and FACS-sorted into five highly...
GSE80467: Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs.
We have generated stable human ESCs (H9) expressing control or DAP5-targeting shRNA. Polysome profil...
GSE99250: Kmt2a and Kmt2b Control Memory Function via Different Transcriptional Programs
We have analyzed changes in histone 3 lysine 4 methylation (H3K4me) and gene expression resulting ei...
GSE122818: Expression profiling of pancreatic adenocarcinoma and ductal adenocarcinoma cell lines.
We characterized baseline gene expression profiles for eleven human pancreatic adenocarcinoma and du...
GSE52957: The p53-regulated long noncoding RNA, lincRNA-p21 promotes the expression of Polycomb target genes and enforces the G1/S checkpoint by activating p21 in cis [RNA-seq]
The p53-regulated long non-coding RNA, lincRNA-p21, has been proposed to promote apoptosis and to re...
GSE53380: Kat2a regulates hippocampal memory formation [RNA-seq]
We sequenced mRNA from 24 samples extracted from mouse CA1 tissue to generate the first CA1-specific...
GSE53743: Translational profiling in the unfolded protein response
The unfolded protein response (UPR) couples cellular translation rates and gene expression to the pr...
GSE54390: mRNA profiling of GGT-HIF1aM3 (-HIF1M3, TRACK) kidney cortex
The complete transcriptomes of kidney cortex from 3 TRACK/-HIF1M3 ~15 month old TG+ male mice and 3 ...
GSE49571: Long-term exposure to low-concentrations of Cr(VI) induce DNA damage and disrupt the transcriptional response to benzo[a]pyrene
Living organisms are exposed on a daily basis to widespread mixtures of toxic compounds. Mixtures po...
GSE121795: Assessement of transcriptional consequences of CD27 signaling on Tregs during Th17 polarization
The goal of this study was to identify transcripts that were differentially expressed in untreated v...
GSE74697: Long non-coding RNAs in psoriatic and healthy skin
In this study, we used RNA-sequencing to profile the long non-coding RNA (lncRNA) transcriptome in l...
GSE121043: Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE50983: MAEL-dependent selective processing of pachytene piRNA precursors and translation of spermiogenic mRNAs
Piwi-interacting small RNAs (piRNAs) of fetal prospermatogonia of mice have been strongly implicated...
GSE56905: Study of the cross-talk between two distant tumors
We demonstrated that a visceral immunosuppressive tumor can influence a distant, normally-responsive...
GSE54409: Pathways Disrupted in Human ALS Motor Neurons Identified Through Genetic Correction of Mutant SOD1
Although many distinct mutations in a variety of genes are known to cause Amyotrophic Lateral Sclero...
GSE98258: Non-cell autonomous Otx2 homeoprotein regulates visual cortex plasticity through Gadd45b
A better understanding of how Otx2 regulates plasticity in the visual cortex requires that its non-c...
GSE60781: Identification of subset-specific dendritic cell progenitors reveals early commitment in the bone marrow [RNA-Seq]
Dendritic cells (DCs) are antigen sensing and presenting cells that are essential for effective immu...
GSE133820: Transcriptomic analysis of class I odorant receptor enhancer deletion [LD]
We used RNAseq based transcriptome analysis to compare gene expression changes in the olfactory muco...
GSE57745: Transposon expression kinetics in Dnmt3L-/- developing testes [RNA-seq]
We examined the kinetics of production of mRNAs and small RNAs derived from transposable elements du...
GSE122991: Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells.
The purpose of this study was to identify genes regulated by NEUROD1 in insulin expressing cells dif...
GSE94839: Differentially expressed genes between SPOPmut and control in mouse prostate organoids
To provide further insight to the signaling pathways deregulated by SPOP mutation and determine the ...
GSE121082: Comprehensive Analysis of TCR- Repertoire in Patients with Neurological Immune-mediated Disorders
Infiltrating T-lymphocytes from the peripheral blood into the central nervous system (CNS) play a dy...
GSE53837: Allelic expression mapping across cell lineages reveal repressor disruption among disease SNPs
Most variants associated to diseases are located in non-coding regions of the genome, and are though...
GSE54853: RNA-seq of C.elegans and M.musculus in the presence and absence of D-Glucosamine (GlcN)
D-Glucosamine (2-amino-2-deoxy-D-glucose, C.A.S.# 3416-24-8) (GlcN) is a freely available and common...
GSE50172: mRNA expression profiles of WT and MLL4-/- during brown preadipocyte differentiation
Enhancers play a central role in cell-type-specific gene expression and are marked by H3K4me1/2. Act...
GSE118766: Activation of a novel ULK1-MLK3-ERK5 pathway by the IFNg receptor is required for IFNg-inducible antiviral responses
Although well established that signal transducer and activator of transcription 1 (STAT1) activation...
GSE117993: Transcription profiles of rectal biopsies obtained during diagnostic colonoscopy for pediatric inflammatory bowel diseases.
RNA was isolated from rectal biopsies from 190 pediatric patients undergoing diagnostic colonoscopy ...
GSE61748: Transcriptome analysis of Foxj3 or Zbtb18 stable expressed embryonic stem (ES) cell lines
To understand the specific mechanism by which Foxj3 and Zbtb18 control RA-induced neural directional...
GSE94566: A p53 super-tumor suppressor reveals a tumor suppressive p53-Ptpn14-Yap axis in pancreatic cancer
The p53 transcription factor is a critical barrier to pancreatic cancer progression. To unravel mech...
GSE52069: Maternal hematopoietic TNF, via milk chemokines, programs hippocampal development and memory
TNF is a proinflammatory cytokine with established roles in host defense and immune system organogen...
GSE53053: High-throughput integration of metabolic and transcriptional profiles reveals major metabolic regulators of macrophage polarization
Macrophages polarize to divergent functional phenotypes depending on their microenvironment in a hig...
GSE53386: Single-cell RNA-Seq transcriptome analysis of circular RNAs in mouse embryos
We reported a new method of single-cell universal poly(A)-independent RNA sequencing (SUPeR-seq) to ...
GSE52490: Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation
Using strand specific RNA-seq to assess the EBV transcriptome during reactivation of Akata cells, we...
GSE53697: RNAseq in Alzheimer's Disease patients
Human brain samples from healthy, early and advanced Alzheimer's Diseased patients were subjected to...
GSE53993: Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line
To systematically investigate early host transcriptional response to HIV-1 infection, including poly...
GSE55163: Genome-Wide Profiling of miRNA-mRNA regulatory network in Skeletal Muscle with Aging [mRNA]
Skeletal muscle degenerates progressively, loses mass (sarcopenia) along in years, and leads to redu...
GSE67117: Identifying signals from the skeletal muscle niche that regulate satellite cell function
Skeletal muscle is the most common tissue in the body. Its continued maintenance and regeneration th...
GSE55190: JNK-mediated control of gene expression in liver
RNAseq analysis of gene expression in Liver of Control and JNK deficient mice fed a control or a Hig...
GSE55689: Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
Gene expression analysis of purified hematopoietic stem and progenitor cells isolated from low to in...
GSE53074: Transcriptome analysis of cells of different cycling speed during Yamanaka reprogramming
Reprogramming somatic cells to induced pluripotency by Yamanaka factors is usually slow and ineffici...
GSE130437: Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib
While targeted therapies directed against cancer cells have proven effective, their clinical benefit...
GSE120353: Transcriptional profile of WT, p53 -/- and p53R172H esophageal cells
We report different transcriptional profiles of WT, p53-/- and p53R172H cells derived from mouse eso...
GSE53683: A mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia [HTS]
The plasma cell transcription factor XBP1 is critical for terminal differentiation of B cells into p...
GSE98280: Function of Sox2 and Klf4 during SKM reprogramming
Differentiated somatic cells can be reprogrammed into induced pluripotent stem cells by ectopic expr...
GSE120336: Tamoxifen therapy in a murine model of myotubular myopathy (TAM4MTM)
Purpose: The goal of this study was to investigate the transcriptional profile of genes expressed in...
GSE62270: Single-Cell mRNA Sequencing Reveals Rare Intestinal Cell Types
Understanding the development and function of an organ requires the characterization of all of its c...
GSE52778: Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications
Rationale: Asthma is a chronic inflammatory airway disease. The most common medications used for its...
GSE53698: RNAseq in IMR-32 neuroblastoma cells
IMR-32 cells were subjected to lentiviral YRNA infection or nELAVL RNAi and/or UV stress followed by...
GSE121179: Next generation seuquencing of 3D breast cancer cell culture in synthetic hydrogels presenting either a collagen mimic or laminin mimic
MDA-MB-231 (ER-) and T47D (ER+) breast cancer cells were encapsulated in synthetic hydrogels, forme...
GSE62704: A negative feedback loop of transcription factors specifies alternative dendritic cell chromatin states (RNA-Seq)
During hematopoiesis, cells originating from the same stem cell reservoir differentiate into distinc...
GSE121992: Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human adult erythroid cells
As high fetal hemoglobin (HbF) levels ameliorate the underlying pathophysiologic defects in sickle c...
GSE53105: Next-generation sequencing facilitates quantitative analysis of diaphysis and metaphysis from femur of 5-week-old Dlx3Oc-cKO and wild type (WT=Dlx3+/+) mice transcriptomes
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE62734: Intrinsic Protection From Leukemic Transformation at The Level of Hematopoietic Stem Cells
Genome wide RNA-seq from pGM and HSCs in response to expression of the MLL-ENL fusion gene SOURCE: S...
GSE115389: RNA-Seq analysis of HIF-2a-responsive genes in clear-cell renal cell carcinoma
We performed RNA-Seq analysis of wildtype and three EPAS1-/- 786-O single cell clones generated by C...
GSE53789: RNA-sequencing reveals oligodendrocyte and neuronal transcripts in microglia relevant to central nervous system disease
Expression profiling of distinct central nervous system (CNS) cell populations has been employed to ...
GSE53280: Transcriptomic profiling of HeLa cells infected with Salmonella Typhimurium
We evaluated the transcriptome changes induced by infection with Salmonella (20 hpi, MOI 100). SOURC...
GSE102923: Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles
We have investigated the genomic and epigenetic consequences of co-culturing colorectal carcinoma ce...
GSE55060: Scml2 establshes germline-sepcific epigenome
we identify Scml2, a subunit of a germ cell-specific polycomb repressive complex 1 (PRC1), as a crit...
GSE111459: Tuberculous Meningitis in Pediatric Patients
Whole blood transcriptional profiles in children with or without tuberculous meningitis (TBM) were c...
GSE45982 (mouse): EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation
The EZH2 histone methyltransferase is highly expressed in germinal center (GC) B-cells and targeted ...
GSE102865: Sp8 and Sp9 Coordinately Promote Striatal Medium Spiny Neuron Production through Activating Six3 Expression [RNA-seq]
Purpose: To assess changes in gene expression profiles from the E16.5 no cre littermate control stri...
GSE130903: Short and long-term effects of CDK4/6 inhibition on early stage breast cancer
CDK4/6 inhibitors are used in the treatment of advanced estrogen receptor (ER)(+) breast cancer (BC)...
GSE53510: Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells
We profile the expression pattern of human pulmonary microvascular endothelial cells (HPMECs) at dif...
GSE103246: RNAseq in control and shQk KD mouse neural stem cells
We sequenced mRNA from mouse primary cultured neural stem cells infected with control or shQk lentiv...
GSE53779: The RNA-binding protein RBM47 suppresses metastatic breast cancer progression
Through integrative analysis of clinical breast cancer gene expression datasets, cell line models of...
GSE89945: RNA-Seq with wild type mESC, wild type NPC and Phc1 knock-out ESC
Master regulatory genes require stable silencing by the Polycomb-Group (PcG) to prevent improper exp...
GSE57680: RNA-sequencing of luminal epithelium and stroma cells isolated by LCM from pseudopregnant day 4 Msx1/Msx2 knockout and control uteri
We recently demonstrated that Msx genes, which encode muscle segment homeobox (Msh) transcription fa...
GSE46846: Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3K Inhibition Through PIK3IP1
The RNA-seq data presented in this study include libraries from Mantle Cell Lymphoma (MCL) tumor cel...
GSE49321 (mouse): Improved Smart-Seq for sensitive full-length transcriptome profiling in single cells
Improved Smart-Seq for sensitive full-length transcriptome profiling in single cells. SOURCE: Rickar...
GSE55581: Diet-induced chromatin remodeling in mice livers
The tissue-specific packaging of the genome into the nucleus through chromatin is fundamentally invo...
GSE53545: Region-specific identity of small intestinal stem cells from the ileum and jejunum
We report the expression profiles of three stem-cell varieties derived from the ileum and jejunum, f...
GSE58836: Chromatin and signaling pathways in reprogramming
Reprogramming intermediates (pre-iPSCs) were subjected to control DMSO, ascorbic acid (AA), 2i ( MAP...
GSE49831: Differential Protein Occupancy Profiling of the mRNA Transcriptome
Protein-RNA interactions are fundamental to core biological processes, such as mRNA splicing, locali...
GSE53595: Stage-specific control of early B cell development by the transcription factor Ikaros
Ikaros is an essential regulator of lymphopoiesis. Here, we studied the B-cell-specific function of ...
GSE54074: An atlas of TNF--responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Sequencing of 5'ends of RNA molecules from Caco-2 cells +/- TNFa stimulation SOURCE: Berit Lilje (be...
GSE55596: Transcriptome Analysis of Follicular Helper T cells, Central Memory Precursors, and Terminal Effecter Th1 Cells from Wild Type and Stat3fl/fl Cd4cre mice
Purpose: To compare the transcriptomes activated CD4 T effector cell populations in the presence and...
GSE54704: miR-125b: A Rheostat of Growth versus Stress-Induced MAPKs That Governs Stemness and OncomiR Addiction in Skin
We analyze the globel gene expression changes in the tumor initiating cells of regressing miR-125b a...
GSE48764: RNA-seq transcriptome analysis of Nestin-GFP-peri and -GFP-retic bone marrow stromal cells
Cell cycle quiescence is a critical feature contributing to haematopoietic stem cell (HSC) maintenan...
GSE55633: Gene expression profile of metastasis-associated neutrophils
The goal of this experiment was to determine gene expresssion differences between neutrophils from e...
GSE104156: Single-cell RNA-seq (10X Genomics Chromium) of MGE, CGE, cortical and subcortical regions of E13.5, E18.5 and P10 mice
Single-cell RNA-seq to profile a developmental time course of interneuron development, measuring the...
GSE55621: Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) controls hippocampal neural stem cell conversion into progenitor cells
Neural stem cells (NSCs) continuously produce new neurons within the adult mammalian hippocampus. Ho...
GSE54107: Netrin-1 facilitates somatic cell reprogramming by limiting Dcc pro-apoptotic activity.
The generation of induced pluripotent stem (iPS) cells holds great promise in regenerative medicine....
GSE54729 (mouse): Transcriptome profiling of a mouse model of alveolar soft part sarcoma
In order to dtermine how well a mouse genetic model of alveolar soft part sarcoma (ASPS) mimics the ...
GSE58757: Extensive crosstalk between lncRNAs and mRNAs in mouse stem cells
To determine the temporal variation of mRNA levels, we collected and sequenced poly-adenylated RNA f...
GSE33592: Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq
We mapped and quantified poly(A) sites in BJ and MCF10A cells under proliferative, arrested and tran...
GSE53001: Subclone of resistant CT26 murine tumor shows high sensitivity to VA7 virotherapy: A novel system to study innate immunity and antigen dominance in oncolytic immuno-virotherapy
Recently, attenuated Semliki Forest virus vector VA7 completely eliminated type I interferon (IFN) u...