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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Pre-B and pre-T lymphocytes must orchestrate a transition from a highly proliferative state to a qui...
We have utilized advanced RNAi technology to dynamically restore and subsequently knock down endogen...
To define H3K27me3 modified genes in intestinal stem, progenitor and epithelial cells, we performed ...
DCIS is a non-invasive precursor lesion to invasive breast carcinoma. We still have no understanding...
The adult mouse subependymal zone (SEZ) provides a niche for mammalian neural stem cells (NSCs). How...
Transcriptome of skin from Acne inversa lesions show specific alterations compared to healthy donor ...
Objectives: Idiopathic pulmonary fibrosis (IPF) is a complex disease in which a multitude of protein...
Emerging evidence suggests that various epigenetic mechanisms play important roles in regulating adu...
RNA-seq analysis was performed using RNA isolated from three tumor models (GL261 glioma, LLC Lewis l...
RNA expression profiles are not significantly altered by DDX3 WT or R534H expression as well as by 4...
We evaluated changes in mRNA stability and transcription using 4sU metabolic pulse labeling across a...
Prdm14 is a sequence-specific transcriptional regulator of embryonic stem cell (ESC) pluripotency an...
Comparison of ribosome associated RNA between Ctrl vs EW (or SD) and EW (or SD) vs EWFxr1 (or SDFxr1...
Gastrocnemius muscle biopsies were obtained from 15 health older adults without peripheral artery di...
MECP2 is critical for proper brain development and expressed at near-histone levels in neurons, but ...
We generated RNAseq profiles from Small Airway Epithelial Cells (SALE) expressing either KRAS G12V o...
We explored the role of the lysine-methyltrasferase G9a in the control of DNA methylation during mou...
NOTCH/RBPJ/MAML ternary transcriptional complex binds to regulatory element and drives gene expressi...
DUX4-induced gene expression was compared in the presence vs. absence of the p300 inhibitor, iP300w ...
Obesity, and visceral adiposity in particular, increases the risk of common metabolic diseases, incl...
Changes in DNA methylation are required for the formation of germinal centers (GC), but the mechanis...
We examined the role of PELP1 in E2-ER-mediated transcription in the hippocampus under conditions of...
Mice lacking components of the linear ubiquitin chain assembly complex (LUBAC) exhibit defects in th...
We analyzed the effect of DCP1A knockout on total RNA population in undifferentiated mouse embryonic...
MLL3/MLL4 are H3K4me1/2 methyltransferases enriched on enhancers. CBP/p300 are H3K27 acetyltransfera...
Through the analysis of mouse liver tumours promoted by distinct routes (DEN exposure alone, DEN exp...
Aim: Transcriptional analysis of the colon of adult Nkx2.2flox/flox;Villin-Cre (Nkx2.2int) mice vers...
Here we report the discovery of ABBV-744, a first in class, highly potent and selective inhibitor of...
AGRP neurons are a hypothalamic population that senses physiological energy deficit and consequently...
Three triple negative breast cancer cell lines (MDAMB231, SUM159, and HCC1806) were treated with sma...
T follicular helper (TFH) cells promote affinity maturation of B cells in germinal centers (GCs), wh...
Dox-inducible YAP5SA-GFP/nGFP were treated with Doxycycline for 24 hours each and compared to non-tr...
Mutations in the poly(A) ribonuclease (PARN) gene cause telomere diseases including familial idiopat...
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 SOURCE: Frithjof Glowinski...
The Adenomatous Polyposis Coli (APC) tumor suppressor is mutated in the vast majority of human color...
Here, we elucidated whether miR-200 family members control RNA-binding protein quaking (QKI), a newl...
The sequential activation of distinct developmental gene networks governs the ultimate identity of a...
Intestinal macrophages (IMs) are uniquely programmed to tolerate exposure to bacteria without mounti...
HEK293 cells were heatshocked and differentially expressed transcripts were identified SOURCE: Jon B...
This experiment aims to identify the biological pathways and diseases associated with the cytokine I...
Significance of RNA methylation in the context of HIV-1 infection in human T cells SOURCE: Christoph...
Accumulating evidence indicates that long noncoding RNAs can interact with microRNAs to regulate tar...
Following implantation, mouse epiblast cells transit from a nave to a primed state in which they are...
We report the application of single-molecule-based RNA sequencing technology for comparing the trans...
Insults to cellular health cause p53 protein accumulation and loss of p53 function leads to tumorige...
Gemcitabine resistance is currently the main problem of chemotherapy for advanced pancreatic cancer ...
microRNA plays important roles in tumor initiation and progression. Here we showed that, one of the ...
Abnormal placentation in cloned animals remains an unsolved problem. We demonstrated the involvement...
This study describes the transcriptome profiling of: 1) mouse ES cells in LIF/KSR medium; 2)EpiSCs i...
To analyze roles of histone H3 tri-methylation for transcription in retina, global transcription pat...
RNA-seq of breast tumor from Pik3caH1047R/+ mammary gland transduced with single or pooled lentiviru...
Polycomb repressive complex 2 (PRC2) maintains developmental regulator genes in a repressed state th...
Norm mouse hepatocyte-derived extracellular vesicles were used to treat CCl4-injured mice and the he...
TET-family dioxygenases oxidize 5-methylcytosine (5mC) in DNA, and exert tumor suppressor activity i...
The data generated here shows increased interferon gamma gene signatures in Elf5- tumor cells in C3...
Recurrent mutations in the spliceosome are observed in several human cancers but their functional an...
Objective: To assess safety in women of tenofovir disoproxil fumarate (TDF) polyurethane intravagina...
Analysis of Kupffer cells at gene expression level. The hypothesis tested in the present study was t...
The immune system depends on a balanced interplay among a variety of specialized cell types transiti...
Untreated mice or mice treated with paracetamol, in the presence or absence of TSA, were culled afte...
Abstract:The pRb tumor suppressor protein associates with chromatin and regulates gene expression. N...
ILC2 are potent producers of IL-5 and IL-13 and Th2 cytokines have been found to promote neurogenesi...
Alterations of IKZF1, encoding the lymphoid transcription factor IKAROS, are a hallmark of high risk...
We found NF-kB signaling as a major target of miR-26 based on an analysis of the changes in gene act...
We performed SMAD2/3 ChIP-seq analysis in MCF10A MII cells. To validate whether the changes in SMAD2...
To understand the genes and pathways that may potentially drive nasopharyngeal carcinoma (NPC) patho...
Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans, and has been implica...
Medial prefrontal cortices (mPFCs) were dissected from the brian of control of antibiotic-treated 10...
To improve the maturity and reduce the heterogeneity of iPSC-cardiomyocytes, we addressed the divers...
Mitochondrial biogenesis and metabolism recently emerged as critical modulators of stemness properti...
The goals of this study are to analyze the transcriptome profiling (RNA-seq) after PBX3 overexpressi...
ChIP-Seq data of HDAC3 in mouse C57BL/6J hippocampus and RNA-Seq data of hippocampal CA1 in control ...
MicroRNAs have emerged as key regulators of B cell fate decisions and immune function. Deregulation ...
The cellular response to replication stress requires the DNA-damage responsive kinase ATM and its co...
Here, we find that the B cell lymphoma 6 (BCL6) repressor is enriched upon feeding and converges gen...
Retrotransposons comprise a staggering 40% of the mammalian genome. Among them, endogenous retroviru...
Histone variant H3.3 is incorporated into various chromatin domains by distinct chaperones including...
Activating mutations in the proto-oncogene KRAS are a hallmark of pancreatic ductal adenocarcinoma (...
A major problem with linking transcription factor binding to function is that many factors bind to a...
The juvenile onset of spermatogenesis in mice is analyzed by combining cytological and transcriptomi...
We aim to the investigate the role of tamoxifen in breast cancer progression. LCC2 and MCF-7 cells w...
Mental disorders (MDs) such as intellectual disability (ID), autism spectrum disabilities (ASD) and ...
In order to understand the molecular effects of PARP-1 on basal and signal-regulated transcription...
ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, is frequently mutated in cancer. Defi...
Disruption of the MECP2 gene leads to Rett syndrome (RTT), a severe neurological disorder with featu...
The transcriptional profile of WapCre;Rank;Brca1;p53 and WapCre;Brca1;p53 mouse primary mammary tumo...
We developed a new single cell sequencing method to simultaneously identify RNA TSS and TES at singl...
Purpose: To compare the transcriptome of MESP1-mTomato reporter cells at undifferentiated state, car...
We hypothesized that the circRNA will play an important role in the progresion of gallbladder cancer...
Neuropathic pain is a complex chronic condition, characterized by a wide range of sensory, cognitive...
Analysis of adult progenitor cells depleted for DDX6. Results provide insight into the regulation of...
DNA methylation is the net result of deposition by DNA methyltransferases (DNMT1, 3A and 3B) and rem...
miRNA sponge, a special class of miRNA target, has been emerging as a pivotal player in miRNA media...
In this study we show that ascorbate (vitamin C) shifts the transcriptome of melanoma cells, and de...
Purpose: The aim of this study is to identify genes that are differentially expressed in the differe...
The transporter which uptakes pyruvate into the mitochondria during pyruvate oxidation, called the M...
Allergy is one of the least understood immunological response partly due to the diversity of allerge...
Total mRNA seq was perfomed on widtype and Ret null male mouse embryonic gut at E10.5 SOURCE: Sumant...
Accumulation of misfolded proteins in the endoplasmic reticulum (ER) triggers the unfolded protein r...
The hypothesis is that HIV affects TRM, by decreasing their numbers and possibly affecting their fun...