Explore curated data sets and assays
Pluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for access
Sequencing-based assays page 49
Store large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
GSE90797: Molecular reprogramming of granulocyte/macrophage progenitor (GMP) clusters upon induction of BCR/ABL oncogene
Single cell RNA Seq and bioinformatic analysis are used to study what processes are important for th...
GSE97078: AG-221 as an effective and on-target therapy in IDH2 mutant AML
Herein we developed a multigenic AML model with inducible expression of IDH2R140Q and constitutive e...
GSE87419 (mouse): Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (RNA-seq)
Targeting the dysregulated BRaf-MEK-ERK pathway in cancer has increasingly emerged in clinical trial...
GSE136690: Transcriptional profiling of neurons in the thalamus of a Slc17a6-TRAP (JX883) mouse line
TRAP translational profiling is a method that allows investigators to genetically characterize speci...
GSE143695: Gene expression profiles of WT and Vil-CREPTKO intestinal cyrpts
Intestinal stem cells (ISCs) residing in the crypts are critical for the continual self-renewal and ...
GSE154614: Gene expression and polysome profiling data of E-Myc B-lymphoma cells
Acute response to combinatorial ribosome-targeting therapy in vivo is associated with downregulation...
GSE154551: Notch activity determines a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features [L-NICD]
Hepatocellular carcinoma (HCC) is the predominant primary liver cancer and an increasing cause of ca...
GSE134864: H2BG53D mutation in PDAC
Study was conducted to understand the effect of the cancer associated H2BG53D mutation in PDAC. Usin...
GSE87592: Expression profiling by high throughput sequencing and transcriptome-wide association study study the metabolic mechanism of the formation of atorvastatin lactone and the risk to statin-induced myotoxicity
Statin-induced myotoxicity (SIM) is one of the principal reasons for atorvastatin (AT) non-adherence...
GSE86418: Transcriptomic profiling of dorsal root ganglia of transgenic sickle and control mouse models for studying genetic signatures of pain in sickle cell disease
We sequenced mRNA from the dorsal root ganglion (DRG) of transgenic mouse models of sickle cell dise...
GSE140217: The biochemical basis of microRNA targeting efficacy [4]
MicroRNAs (miRNAs) act within Argonaute proteins to guide repression of mRNA targets. Although vario...
GSE86338: RNA profiling to describe the transcriptional change during white fat browning, brown fat activity and inactivation
Enhancing brown fat activity and promoting white fat browning are attractive therapeutic strategies ...
GSE80187: Genome-wide analysis of tumor suppressive programs during p53-induced regression of Myc-driven lymphomas [RNA-Seq]
The tumor suppressor p53 is a transcription factor that controls the response to stress. Here, we di...
GSE86336: m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
HeLa cell chromatin associated nascent pre-mRNA (CA-RNA) contains many unspliced introns and m6A in ...
GSE79137: Repression of interstitial cell identity in nephron progenitor cells by Pax2 establishes the nephron-interstitium lineage boundary throughout mammalian kidney development
The kidney contains the functional units, the nephrons, surrounded by the renal interstitium. Previo...
GSE85887: The impact of YTHDF2 knockout on the distribution of 5-methylcytosine in RNA
5-methylcytosine is an important epigenetic modification found in both DNA and RNA. Transcriptome-wi...
GSE131555: Capture of mouse and human stem cells with features of formative pluripotency [mouse, RNA-Seq 2]
Pluripotent cells emerge as a nave founder population in the blastocyst, acquire capacity for germli...
GSE116096: Gene expression in isolated epithelial and stromal cells from day 4 pregnant uterus
To detect the gene profiles in epithelial and stromal cells, these cells are isolated from three ind...
GSE90795: Transcriptomic analysis of intestinal epithelial Sox4 knockout
Sox4 is expressed in intestinal stem cells (ISCs) and early intestinal progenitors. The regulatory r...
GSE89056: Integrative analysis of reprogramming human fibroblast cells to nave pluripotency [RNA-seq]
Derivation of human nave cells in the ground state of pluripotency provides promising avenues for de...
GSE92910: Gene expression profiling of histone deacetylase inhibition in triple-negative breast cancer
Analysis of changes in gene expression levels after after prolonged exposure of triple-negative brea...
GSE81809 (mouse): Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo
Reprogramming of cardiac fibroblasts into induced cardiomyocyte-like cells (iCMs) in situ represents...
GSE86297: Transcription and chromatin determinants of the rate of de novo DNA methylation in oocytes
We generated genome-wide methylation and transcriptome maps of size-selected, growing oocytes to cap...
GSE86396: Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development [RNA-Seq]
Purpose: To asses changes in gene expression profiles from the P11 no cre littermate control olfacto...
GSE79260: A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus
During vertebrate limb development, Hoxd genes are regulated following a bimodal strategy involving ...
GSE86316: Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells
We performed RNA-seq in MCF-7 cells after silencing of MEN1 using small hairpin RNA's directed at th...
GSE85891: Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function
To increase our understanding of psoriasis, we utilized RNA-seq to assay the transcriptomes of skin ...
GSE86113: Investigating B cell stimulation in ubiquilin-1 KO mice
Ubiquilins are a family of proteins involved in proteasomal degradation of mislocalized membrane pro...
GSE86417: RNA-seq of mouse embryonic stem cell states expressing Esrrb, Tbx3, and Zscan4
We develop a theoretical-computational framework for inferring cell state transition dynamics, and a...
GSE97519: Single-cell RNA-seq of NR5A1-eGFP positive cells of the developing mouse testis from E10.5 to E16.5
Purpose: We performed a time-course single-cell RNA-seq of the somatic cells of the XY mouse gonads ...
GSE87104: RNA-seq Analysis of Wild Type and Ptpn11-deficient cerebellar Transcriptomes
We have recently discovered that deletion of Ptpn11, which codes for protein tyrosine phosphatase Sh...
GSE89035: Interruption of Hepatic Glucagon Signaling Reveals a Hepatic--Islet Cell Axis Where L-Glutamine Stimulates -Cell Proliferation
Decreasing glucagon action lowers blood glucose and may be a useful therapeutic approach for diabete...
GSE83217: RNA sequencing to identify common targets for regulation of cognition
siRNA BDNF and siRNA HDAC4 treatment impaired cognition SOURCE: Eleonore Beurel (ebeurel@miami.edu)...
GSE104910: Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells
EZH2, the catalytic component of the Polycomb repressive complex 2 (PRC2), silences gene transcripti...
GSE132776: NHLRC1 re-expression in cancer cells
Flag-tagged NHLRC1 expression in three different cancer cell lines SOURCE: ramon,chang,sun (ramon.su...
GSE80326: Mouse oocytes suppress mir-322-5p expression in ovarian granulosa cells
This study tested the hypothesis that oocyte-derived paracrine factors (ODPFs) regulate miRNA expres...
GSE84987: Molecular role of the PAX5-ETV6 oncoprotein in promoting B cell acute lymphoblastic leukemia
PAX5 is a tumor suppressor in B-ALL, while the role of PAX5 fusion proteins in B-ALL development is ...
GSE89057: RNA-seq of SOX5 overexpressing primary human neuronal progenitors
Purpose: The goal of this study was to assess gene expression changes in neurons overexpressing SOX5...
GSE98139: Whole blood gene expression in adolescent Chronic Fatigue Syndrom (CFS) by RNA-Seq
This study compared whole blood gene expression in CFS adolescent and healthy controls, and explored...
GSE95024: p53-induced apoptosis is specified by a translation program regulated by PCBP2 and DHX30.
Activation of p53 by the small molecule Nutlin can result in a combination of cell cycle arrest and ...
GSE89677: Long-term expansion of functional pancreatic islets on a laminin-521 matrix and curative transplantation into diabetic mice
In this study we show, for the first time, that whole islets can be cultured and significantly expan...
GSE130003: Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells
We report the gene expression profiles of gastric squamous-columnar junction cancer derived from the...
GSE84794: Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding [RNA-seq]
Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chr...
GSE86333: SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq]
RNA-Seq experiments on SETBP1-G870S and Empty cells was performed in order to assess if the presence...
GSE87110: Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu
In a forward genetic screen we identified a Chlamydia trachomatis L2/434/Bu mutant that causes rapid...
GSE85606: Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq]
Cancer Associated Fibroblasts (CAFs) play an active role in tumourigenesis. It is unknown how the pe...
GSE99331: Germline Chd8 haploinsufficiency alters brain development in mouse
We examined the impact of germline heterozygous frameshift Chd8 mutation on neurodevelopment in mice...
GSE89775: Loss of EGFR-DDEF1 signaling in metastatic and unresectable hepatoblastoma
We report that the application of PE sequencing of mRNA in hepatoblastoma patient biopsies effective...
GSE80044: RNA-seq of Lmnb1-/- and Lmnb1+/- olfactory lineages
Lamins, the major components of the nuclear lamina, have diverse functions in many cellular processe...
GSE90725: Obesity Alters the Composition and the Activity of the Hematopoietic Stem Cell Compartment Through Dysregulation of Gfi1 Expression (Bulk RNA-Seq)
Obesity is a chronic organismal stress that disrupts multiple systemic and tissue-specific functions...
GSE90470: Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development
To follow the changes in the transcriptional programs accompanying the specification of the adult IS...
GSE86538: ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines
We performed ChIP-seq on MCF7 cells in an effort to discern differential binding patterns between wi...
GSE89683: Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells [rnaseq]
To follow the changes in the transcriptional programs accompanying the specification, maintenance an...
GSE87890: Molecular profiling of dorsal raphe nucleus Vgat and VGLUT3-expressing neurons
Hunger, driven by negative energy balance, elicits the search for and consumption of food. In mammal...
GSE85908: Single-cell alternative splicing analysis with Expedition reveals splicing dynamics during neuron differentiation
Alternative splicing (AS) generates isoform diversity critical for cellular identity and homeostasis...
GSE80288: Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Msx1-/- tooth mesenchyme Transcriptomes
Mutations in MSX1 cause craniofacial developmental defects, including tooth agenesis, in humans and ...
GSE95822: Length-independent telomere damage drives cardiomyocyte senescence
Ageing is the biggest risk factor to cardiovascular health and is associated with increased inciden...
GSE97615: Human Oral and Cutaneous Wound Healing Transcriptomes
Comparative analysis between oral and cutaneous wound healing in humans using paired and sequential ...
GSE86400: Transcriptome of mouse preimplantation development [C57BL/6 x Cast; WT]
Purpose: The goals of this study are to establish a dynamic roadmap of imprinted X chromosome inact...
GSE86470: Transcriptional profiling of mouse and hamster oocytes
We profiled transcriptomes from mouse GV, MII oocytes and 1 cell embryos and Hamster oocytes. SOURCE...
GSE86491: Comprehensive RNA sequencing of healthy human endometrium at two time points of themenstrual cycle
mRNA, sncRNA and lncRNA show a clear difference in expression between proliferative phase and 79 day...
GSE80354: Gata6 promotes hair follicle matrix progenitor cell renewal by genome maintenance via Edaradd/NF-B
Cell proliferation is essential to rapid tissue growth and repair, but is inherently associated with...
GSE86457: Genes and mechanisms regulated by androgens as possible contributors to the male excess observed in autism [RNA-Seq]
We analyzed androgens effects on human neural stem cells (hNSCs) by RNA-sequencing after either DMSO...
GSE86190: Effect daunorubicin treatment on the transcriptome of HCT116 cells [RNA-seq]
We used RNA-seq to measure the transcriptome of HCT116 in response to the DNA damaging agent daunoru...
GSE87550: Rpph1 regulated Cdc42 and modulated hippocampal pyramidal neurons by competing endogenous miR-330-5p
To build up competing endogenous RNA regulatory network based on APP/PS1 transgenic mice model and v...
GSE147152: Genome-wide analysis of gene expression in EBV(+) GC cell lines [RNA-seq]
We analysed gene expression in EBV(+) GC cell lines to elucidate their contribution to tumorigenesis...
GSE115769: RNA-Sequencing of carnosine treated wild-type BDF1 (WT) and transgenic Thy1-aSyn mice
Mitochondrial dysfunction plays a central role in the pathogenesis of neurodegenerative diseases suc...
GSE112041: RNA-seq in Smchd1 wild-type and Smchd1 null presomitic mesoderm from E9.5 embryos
We sought to examine whether the non-canonical SMC protein Smchd1 plays a role in chromosome conform...
GSE114062: Comparison between a mouse line selected for high voluntary wheel running and control line in two brain regions, cerebellum and striatum
The goals of this study were: 1) to compare the transcriptome of a mouse line selected for high volu...
GSE116469: Transcriptomic changes from iPSC-derived RPE due to MFRP and C1QTNF5
RNA-seq from iPSC-derived RPE looking at both loss of MFRP and treatment with C1QTNF5 SOURCE: Steven...
GSE128243: Single-cell RNA-seq of human peripheral blood NKT cells
NKT cells are potent immune regulators and skew immune responses toward either inflammation or toler...
GSE128074: Single-cell RNA sequencing of basophils from mouse bone marrow
We performed single-cell RNA-sequencing of Lin- Sca1- FcRI+ bone marrow cells from mice SOURCE: Joak...
GSE120582: The mole genome reveals regulatory rearrangements associated with adaptive intersexuality (RNA-Seq)
Linking genomic variation to phenotypical traits remains a major challenge in evolutionary genetics....
GSE114509: RNA-seq of the lacrimal gland epithelial tissue in control vs Pea3-depleted tissue in mouse embyro
The goal of the study is to find the transcriptional targets downstream of Pea3-mediated signaling i...
GSE112772: Sufu and Spop cooperate to suppress SHH medulloblastoma tumorigenesis via regulation of Gli2 protein stability [RNA-seq]
GLI2 overexpression is a hallmark in SHH subgroup of medulloblastoma (SHH MB). Here we profile the t...
GSE135984: BMP2 and GSK126 synergize to induce expression of osteogenic genes
BMP2 and GSK126 synergize to induce expression of osteogenic genes SOURCE: Asha Nair (nair.asha@mayo...
GSE111876: GABA regulates release of inflammatory cytokines from peripheral blood mononuclear cells and CD4+ T cells and is immunosuppressive in type 1 diabetes
This study compared the transcriptome profiling (RNA-seq) of CD3+ T cells from nondiabetic (ND) indi...
GSE114883: Transcriptomic profiling of mock-infected primary CD4+ T cells and a model of HIV latency treated with suberoylanilide hydroxamic acid (SAHA) and Romidepsin (RMD)
Purpose: The goal of this study is to identify host genes whose expression is perturbed in primary C...
GSE79291: Comparison of Glomerular and Podocyte mRNA Profiles in eNOS-/- Diabetic Mice Induced by Streptozotocin
We compared mRNA profiles of isolated glomeruli versus sorted podocytes between diabetic and control...
GSE126516: Next Generation Sequencing of langerhans islets of miR-17-92/106b KO vs control
NGS was used in order to discover novel downstream targets of the miR-17-92/106b clusters. SOURCE: E...
GSE128232: Identification of transcriptional targets of PHF20L1 by RNA sequencing [RNA-seq]
To gain insights into global gene expression regulated by PHF20L1, RNA sequencing (RNA-Seq) experime...
GSE126529: Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma
Identification of gene expression changes following inhibition of GSK-3 in Burkitt lymphoma SOURCE: ...
GSE64098: Transcriptome profiling of human lung cancer cell lines.
Purpose: The aim of this study is to compare different RNA extraction methods using a mixture design...
GSE133995: RNA-seq profiling of adult skeletal muscle after long term conditional knockout of Hic1 [TA RNA-seq]
To determine the effects of long term deletion of the transcriptional repressor Hypermethylated in c...
GSE142560 (human): Gene expression profile of HSPC with cell-intrinsic innate immune signaling activation after LPS treatment
The underlying mechanisms responsible for the competitive advantage of MDS HSPC in an inflammatory m...
GSE85931: Transcriptome profile of murine bone marrow-derived macrophages treated with 15d-PGJ2 or 15d-PGJ2-PC
Purpose: The goal of this study is to investigate the alteration of gene expression pattern induced ...
GSE86318: Effect of SWELL1 gene deletion on gene expression in adipocytes
We used RNA-Seq to detail the global expression changes induced when SWELL1 is genetically deleted f...
GSE69735: Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia
We identified a novel recurrent genetic lesion in T-LGL. Mutations of the tumour suppressor gene TNF...
GSE121083: Oligodendrocyte progenitor cells become regionally diverse and heterogeneous with age
Oligodendrocyte progenitor cells (OPCs), which differentiate into myelinating oligodendrocytes durin...
GSE117394: Molecular analysis of the midbrain dopaminergic niche during neurogenesis
Midbrain dopaminergic (mDA) neurons degenerate in Parkinson's disease and are one of the main target...
GSE115789: Ubiquitin-specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling
The aim is to analyze the transcriptome profiling (RNA-seq) of Mettl3 knockout mesenchymal stem cell...
GSE130143: FIN-Seq: Transcriptional profiling of specific cell types in frozen archived tissue from the human central nervous system
FIN-Seq is a method that allows transcriptional profiling of specific cell types in frozen postmorte...
GSE129142: Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells
We have analyzed RNA-seq data to identify A-to-I editing sites in two groups of samples: one group i...
GSE142333: Transcriptomic dysregulation of SDCCGA8 KO retinal epithelial and immature neuronal cells.
RNA-seq transcirptomic profiling of SDCCAG8-deficient cells generated by gene-editing, identified di...
GSE155063: Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis
The goal of this study is to use bulk RNA-sequencing of the right brain hemisphere to observe the ef...
GSE151550: Transcriptional buffering compensates for eIF4E deficiency 2 in mRNA translation in transformed but not normal cells
This study examined genome-wide translational and transcriptional regulation by the initiation facto...
GSE111724: RNA-seq in Smchd1 wild-type and Smchd1 deleted differentiating male ES cells.
We sought to examine whether the non-canonical SMC protein Smchd1 plays a role in chromosome conform...
GSE128885: RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS)
In order to identify transcript changes in response to DEF , we used human macrophages with or witho...
GSE121080: Single cell RNA-seq resolves lineage-specific activation dynamics of human blood and tissue T cells
Human T cells coordinate adaptive immunity and persist as heterogeneous subsets in tissues and circu...
GSE126326: RNA-Seq of whole kidneys of P8 Six2Cre+KCTD1fl/fl mice and control littermates
RNA-Seq of kidneys lacking the gene KCTD1 in the nephron SOURCE: Alex Marneros Massachusetts General...