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Sequencing-based assays page 48
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GSE80776: Characterization of a spontaneous model of inflammation-derived liver cancer [RNA-seq]
Induction of a protective response to oxidative stress, both from a transcriptional and from a genet...
GSE85143: RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection
mRNA profiles of astrocytes infected with Borrelia burdorferi for 24 hours, 48 hours, and 24 hour u...
GSE83394: Chromatin access at specific genome sites distinguishes intestinal crypt populations with stem cell potential
To define differences in chormatin accessibility and histome modifications in intestinal stem and ep...
GSE85402: Ets homologous factor has critical roles in epithelial dysfunction in airway disease [RNA-seq]
Ets homologous factor (EHF) is an Ets family transcription factor expressed in many epithelial cell ...
GSE85465: Epigenomic Profiling of Primary Gastric Adenocarcinoma Reveals Super-enhancer Heterogeneity [RNA-seq]
Regulatory elements in cancer remain poorly characterized in primary solid tumors. Here we applied m...
GSE85750: Comparison of expression profiles between WT and MG-G1 adult bone marrow LSK cells
GATA1 is repressed in hematopoietic stem cells. To understand the significance of Gata1 gene silenci...
GSE90702: Identification of the embryonic germ cell Meioc-/- transcriptome, MEIOC targets in postnatal testis, and YTHDC2 targets in postnatal testis in mouse
Identification of the embryonic germ cell Meioc-/- transcriptome, MEIOC targets in postnatal testis,...
GSE83991: Transcriptome analysis of mouse lung epithelial cells
Mouse lung epithelial subpopulations (alveolar type 2, basal and airway luminal cells) freshly disso...
GSE89032: Post-transcriptional Gene Silencing Mediated by microRNAs is Controlled by Nucleoplasmic Sfpq [RNA-Seq]
There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus...
GSE114001: Re-evaluating Microglia Expression Profiles Using RiboTag and Cell Isolation Strategies
Transcriptome profiling is widely used to infer functional states of specific cell types, as well as...
GSE86997: Loss of Macf1 abolishes ciliogenesis and disrupts apicobasal polarity establishment in the retina
Microtubule actin crosslinking factor 1 (Macf1) plays a role in coordinated actions of actin and mic...
GSE85018: Germinal-center development of memory B cells driven by IL-9 from follicular helper T cells
A subset of GC B cells that have stopped cycling, upregulated CD38 and downregulated BCL-6 is functi...
GSE85154: The spectrum and regulatory landscapes of intestinal innate lymphoid cells are shaped by the microbiome (RNA-Seq)
Innate lymphoid cells (ILCs) are critical modulators of mucosal immunity, inflammation, and tissue h...
GSE102457: Open housing drives the expression of immune-response genes in the nasal mucosa, but not the olfactory bulb
Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfacto...
GSE83772: The FAM46C gene encodes a non-canonical poly(A) polymerase and acts as an onco-suppressor in multiple myeloma
FAM46C is one of the most frequently mutated genes in multiple myeloma (MM) and encodes a protein of...
GSE86079: RNAseq transcriptome analysis reveals developmental heterogeneity among mouse bone marrow monocyte subsets
Purpose: In our study, we identified a heterogeneity among bone marrow (BM) Ly6Chi monocytes, which ...
GSE86232: ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex
ERK activates ERG-mediated prostate cancer specific gene expression program by phopshorylation induc...
GSE85249: Wnt-responsive mesenchymal cells in dorsal back skin and ventral foot skin
Canonical WNT-signaling is essential for placode formation irrespective of appendage type. At sites ...
GSE156606: Changes of gene expression patterns of Mouse TC-1 cell lines responding to Interferon-gamma [TC-1 cell line]
We report the differences of gene expression pattern of Mouse TC-1 cell lines responding to Interfer...
GSE129024: Engram-specific transcriptome profiling of contextual memory consolidation
Sparse populations of neurons in the dentate gyrus (DG) of the hippocampus are causally implicated i...
GSE83492: Transcriptome analysis of human lung epithelial cells
Human lung epithelial subpopulations (alveolar type 2, basal and airway luminal cells) freshly disso...
GSE157063: Ribosome profiling in DDX3X degron cell lines and covering variants
We describe the subset of transcripts that require DDX3 for efficient translation. SOURCE: Srivats V...
GSE90752: Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells
Direct reprogramming can be achieved by forced expression of transcription factors (TFs). Yet how su...
GSE153192: Combinatorial transcriptional profiling of mouse and human enteric neurons identifies shared and disparate subtypes in situ [Mouse sn-RNA-Seq]
Single-nucleus RNA-Seq of enteric neurons of adult mice, derived from the major regions of the intes...
GSE154474: RNAseq analysis of peripheral blood and synovial fluid neutrophils from rheumatoid arthritis patients
We report changes in gene expression that take place in human neutrophils following migration from p...
GSE86073: Ciliary Hedgehog signaling restricts injury-induced adipogenesis
Injured skeletal muscle regenerates, but with age or in muscular dystrophies, muscle is replaced by ...
GSE84829: Identification of mesothelial-to-mesenchymal gene signature in ascitic fluid-isolated mesothelial cells through RNA-sequencing
RNA-sequencing analysis was carried out on ascetic fluid-isolated mesothelial cells from ovarian can...
GSE103923: RNA sequencing of Foxd1Cre;Smo(flox/-) mutant kidneys
Purpose: To analyze the mRNA content of Foxd1Cre;Smo(flox/-) mutant kidneys.; Methods: We collected ...
GSE81741: Unique Transcriptional Programs Identify Subtypes of AKI
Two metrics, a rise in serum creatinine concentration and a decrease in urine output, are considered...
GSE78962: Dose-Response Analysis of RNA-Seq Profiles in Archival Formalin-Fixed Paraffin-Embedded (FFPE) Samples
Use of archival resources has been limited to date by inconsistent methods for genomic profiling of ...
GSE84958: AKR1C3-mediated adipose androgen generation fuels an adverse metabolic phenotype in polycystic ovary syndrome (PCOS)
RNA-seq samples used to support a study into understanding of the association between androgens and ...
GSE86080: Effect of green tea extract on systemic metabolic homeostasis in diet-induced obese mice; based on RNA-sequencing transcriptome profiles
We investigated the effect of green tea extract on phenotype characteristics and elucidated anti-obe...
GSE85855: Whole transcriptome analysis of reaggregated embryoid bodies treated with IWR-1
We identified distict mesodermal sub-populations based on Endoglin (Eng) and Flk1 expression in Brac...
GSE99010: The synergestic effects of western diet and carbon tetrachloride (CCl4) to develop non-alcoholic steatohepatitis (NASH) and liver tumor in mice
NASH is a combination of hepatic steatosis and severe inflammation, which can lead to fatal liver di...
GSE89811: RNA-seq analysis of bone marrow peri-vascular stromal cells
Fate decisions of haematopoietic stem cells (HSCs) to self-renew or differentiate in response to var...
GSE154575: High-throughput gene expression profiling of human castration-resistant prostate cancer cell lines
We examine the gene expression and chromatin accessibility profiles of four human castration-resista...
GSE97181: Foxp1 expression in forebrain pyramidal neurons controls gene expression required for spatial learning and synaptic plasticity
Genetic perturbations of the transcription factor, Forkhead Box P1 (FOXP1), occur in patients with a...
GSE87452: Human Naive Pluripotency Attained by Transient Inhibition of mTor
Mouse embryonic stem cells (mESCs) are in naive pluripotency that represents the ground state of dev...
GSE96758: Cooperative epigenetic remodeling by TET2 loss and NRAS mutation drives myeloid transformation and MEK inhibitor sensitivity [RNA-Seq]
Recent studies using next-generation sequencing technology have uncovered mutational landscapes of v...
GSE94966: Define roles of JMJD1B in mediating histone demethylation and gene expression
The arginine or lysine methylation status of histones dynamically changes during many essential cell...
GSE90754: Functional Genomic Analyses of hepatic tissue after FOXO1 knockout
To explore the molecular mechanism underlying glucose regulation, we analyzed transcriptome changes ...
GSE85782: Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq]
Obtaining highly purified differentiated cells via directed differentiation from human pluripotent s...
GSE132871: Reconstituted Rela-/- MEF
Protein deamidation is emerging as a post-translational modification that regulates protein function...
GSE87578: Coordinated Activities of Multiple Myc-Dependent and Myc-Independent Biosynthetic Pathways in Hepatoblastoma
Hepatoblastoma (HB) is associated with aberrant activation of the b-catenin and Hippo/YAP signaling ...
GSE125738: Next Generation Sequencing Facilitates Quantitative Analysis of human breast cancer cell T47D and T47D-TR Transcriptomes
To gain new insight into the resistance to hormonal therapy in breast cancer, we generated a tamoxif...
GSE87055: Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA]
We utilize gene expression and open chromatin footprinting data to build a gene regulatory network o...
GSE154676: RNA-seq after CD95 gene knockout in 4T1 cells
We examine the differential RNA expression after knocking out CD95/Fas gene in 4T1 cells SOURCE: Zhe...
GSE93252: RNA Sequencing Reveals Regulation of Marginal Zone B-Cell Differentiation by MicroRNA-146a
Splenocytes were FACS-sorted from Wild-type and Mir146a-/- mice to isolate specific B-cell developme...
GSE85840: Transcriptional changes induced by Brd4 inhibitor, AZD5153, in cancer cell lines
We sequenced mRNA from 12 human cancer cell lines treated with DMSO or AZD5153 for 24h to determine ...
GSE85447: Genetic Variation amongst NHBE donor cells containing various TRPV1 SNPs with and without particulate matter treatments
The goal of our study was to determine the effect the TRPV1 I585V SNP has on lung cells. NHBE cells...
GSE155192: Metabolic stress induced by continuous stimulation under hypoxia rapidly promotes a terminally exhausted state in cytotoxic T lymphocytes
Expression profiling of in vitro generated CD8 T cells and CD8 TIL isolated ex vivo. SOURCE: Amanda,...
GSE157068: Mouse Olfactory Epithelium, Lineage-Traced Injury timecourse K5-Cre ER^T2 > Rosa YFP
The lineage of wild-type horizontal basal cells (HBC) stem cells from the olfactory epithelium were...
GSE97167: RNA-seq on biliary epithelial cells (BECs) of Klf5 LKO mice upon DDC injury
In other to assess functional involvement of Klf5 in DR regulation, we made liver-specific Klf5 knoc...
GSE79035: An oncogenic Ezh2 mutation cooperates with particular genetic alterations to induce tumors in mice and redistributes H3K27m3 through the genome [RNA-seq]
B-cell lymphoma and melanoma harbor recurrent mutations in the gene encoding the EZH2 histone methyl...
GSE112204: Transciptomic analysis of cachectic muscles from metastatic allograft models
RNA sequencing analysis of muscles comparing normal muscles with cachectic muscles isolated from mic...
GSE154832: Age-related transcriptional profiling of phagocytic cells isolated from murine epididymal white adipose tissue
Age-related changes in macrophages are thought to underlie deleterious changes in adipose tissue dur...
GSE99866: Quartz-Seq2: a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads
High-throughput single-cell RNA-seq methods assign limited unique molecular identifier (UMI) counts ...
GSE124944: A Glis3-CD133-Wnt signaling axis regulating the self-renewal of adult murine pancreatic progenitor-like cells in colonies/organoids
Adult pancreatic progenitor cells are a potential source of renewable insulin producing cells that c...
GSE156170: Defining the Teratoma as a Model for Multi-Lineage Human Development
Studying early human developmental processes requires access to a model system that is easy to pertu...
GSE141946: Single Cell RNA-seq of Glioblastoma Tumors and GBOs
Analysis of glioblastoma tissue and corresponding glioblastoma organoids by single cell RNA sequenci...
GSE142072: Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal muscle
The membrane protein Cripto plays a key role in shaping macrophage plasticity in skeletal muscle dur...
GSE143605: Gene expression profiles of irradiated WT and CREPT deleted intestinal epithelium
Intestinal stem cells (ISCs) residing in the crypts are critical for the continual self-renewal and ...
GSE104701: RNAseq analysis of bone marrow endothelial cells
Although endothelial cells (ECs) have been shown to contribute to HSC maintenance in bone marrow (BM...
GSE84724: TADs emerge as a functionally, but not structurally privileged scale in the hierarchical folding of chromosomes
Understanding how regulatory sequences interact in the context of chromosomal architecture is a cent...
GSE109544: Differential gene expression pattern of mouse livers transfected with dual oncogenes (day-7 post-injection data set)
To understand global gene expression patterns of mouse livers upon dual-oncogene transfection, RNA s...
GSE107173: Triple vectors expand AAV transfer capacity in the retina
Maddalena et al. showed that the limited DNA transfer capacity (~4.7kb) of adeno associated viral (A...
GSE89711: Analysis of hypertranscription in E13.5 mouse primordial germ cells
During embryonic development, large-scale reprogramming occurs in primordial germ cells (PGCs) at th...
GSE105085: The age of the hematopoietic microenvironment specifies lineage in MLL-rearranged leukemia [MLL_AF9]
The defining characteristics of leukemia, such as lineage and genetics, are associated with a typica...
GSE114597: TRPS1 is a lineage-specific transcriptional dependency in breast cancer [Seq]
We performed an unbiased cell viability-based pooled shRNA screen on 59 cell lines to identify novel...
GSE88801: Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis
Macrophages play an essential role in the early immune response to Mycobacterium tuberculosis and ar...
GSE117079: The Transcription factor Zeb2 ia required to maintain tissue-specific identities of macrophages [single-cell RNA-seq]
Microarray, Bulk RNA Sequencing and Single cell RNA Sequencing of different murine tissue-resident m...
GSE79929: Examination of gene expression in cerebellum of mouse strains B6J, B6J-nmf205-/-, B6J-Gcn2-/- and B6J-nmf205-/-;Gcn2-/-.
Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the sig...
GSE144511: Transcriptional profile of migrating GABAergic progentitors in the E14 mouse brain following maternal exposure to cypermethrin and restraint stress
The goal of this experiment was to assess transcriptional changes in isolated GABAergic progenitors ...
GSE88706: Effect of PPAR Gamma Agonist Rosiglitazone on Carotid Artery Gene Expression after Knockout of Retinol Binding Protein 7 (RBP7)
To examine the role of retinol binding protein 7 (RBP7) in PPAR gamma mediated regulation of target ...
GSE112031: Targeted reactivation of FMR1 transcription in FXS embryonic stem cells
The aim of this work is to selectively increase transcription from the FMR1 locus in FXS hESC lines ...
GSE85755: Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations
In many gene expression studies, cells are extracted by tissue dissociation and Fluorescence-Activat...
GSE97976: Expression profile of hematopoietic stem and progenitor cells (HSPCs) after conditional deletion of the histone 3 lysine 4 (H3K4) methyltransferase Setd1b in mice
Loss of Setd1b in adult mice using both ubiquitous and hematopoietic-specific deletion strategies ca...
GSE119241: Differential gene expression analysis in BRD4-PROTAC treated diffuse large B-cell lymphoma cell lines
We identified differential gene expression after treatment with BRD4-PROTAC ARV771 in two ABC-like d...
GSE86043: HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons [hnRNPA2B1_RNA-seq_mouse_SC]
HnRNPA2B1 encodes an RNA binding protein associated with neurodegenerative disorders. However, its f...
GSE86261: Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation and Homeostasis by PTF1A [6-day RNA-Seq]
RNA-seq analysis documented mRNA changes in total pancreatic RNA preparations 6 days after Ptf1a ina...
GSE87862: Mov10 in developing brain suppresses retroelements and regulates neuronal development and function
RNA helicase MOV10 participates in RNA-induced gene silencing, nonsense-mediated decay and suppressi...
GSE90081: Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis
Purpose: The goal of the study was to integrate verified signals from previous genetic association s...
GSE90067: Comprenhensive lncRNA expression analysis through normal hematopoiesis and AML
It is well understood how proteins regulate cell fate, both in normal development and disease. Howev...
GSE95102: Post-Transcriptional Regulation of Mouse Neurogenesis by Pumilio Proteins [RNA-Seq]
We employ mRNA-seq to investigate transcriptome of Pum1-Knockout, Pum2-Knockout and WT conditons SO...
GSE102161: Single cell RNA Seq data of BMDM from mouse infected with Salmonella [hundred_ten_singles]
The interaction between a pathogen and a host is a highly dynamic process in which both agents activ...
GSE87624: Next-gen RNA sequencing of human osteosarcoma tumors
Trascriptome analysis of osteosarcoma samples were performed SOURCE: Nuri,Alpay,Temiz University of ...
GSE84379: A Unique Twist-Dependent Progenitor Cell Contributes to Adult Skeletal Muscle [Tw2 vs Pax7 fresh sort]
Skeletal muscle possesses remarkable regenerative potential due to satellite cells, a stem cell popu...
GSE116567: The BCL-2 Inhibitor Venetoclax in Combination with Azacitidine Disrupts Energy Metabolism and Targets Leukemia Stem Cells in Acute Myeloid Leukemia Patients
The manuscript summarizes clinical and laboratory-based evaluation of 33 AML patients treated with a...
GSE115934: Identification of cell type specfici markers for type I and type II Hair cells in the mouse utricle using single cell RNAseq
Single cell RNAseq analysis of hair cells isolated from the mouse utricle at three postnatal time po...
GSE88760: DNA-binding pluripotency factors and DNA demethylases can cooperate to maintain pluripotent stem cell identity even in the absence of Brd4 [RNA-seq]
Histone acetylation and the acetyl-lysine reader Brd4 have recently been implicated in embryonic ste...
GSE98782: Therapeutic Inhibition of Inflammatory Monocyte Recruitment Reduces Steatohepatitis and Liver Fibrosis
The CCR2/CCR5 inhibitor cenicriviroc blocks infiltration of inflammatory monocytes into the liver, t...
GSE147150: Single cell RNA sequencing of dormant and proliferating prostate cancer cells from murine bone metastases
Using the immunocompetent bone-metastatic RM1 murine model of prostate cancer, the transriptomes of ...
GSE79068: Interleukin 4 has Stat6-dependent therapeutic efficacy in acute myeloid leukemia
Acute myeloid leukemia (AML) is associated with poor prognosis, and there is a strong need to develo...
GSE148823: ZEB2-mediated EMT in CRC cell line DLD-1
We report the induction of epithelial-mesenchymal transition (EMT) in the epithelial colorectal canc...
GSE93764: Essential role of the transcription factor Bhlhe41 in regulating the self-renewal and BCR repertoire of B-1a cells
The innate-like B-1a cells provide a first line of defense against pathogens, and yet little is know...
GSE57892: A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors
Next generation sequencing of 28 thymic epithelial tumors (TETs) revealed a high frequency of GTF2I ...
GSE145317: Identification of endothelial derived factors that promote metastasis III
To identify endothelial-derived factors that may instructively drive cancer metastasis, we generated...
GSE147669: RNA-seq on MCF10A cells overexpressed with empty control vectors, TRAM2 and activated-YAP
We performed a CRISPR-based functional genetic screen targeting TEAD4 binding motif located within ...
GSE85799: Statins modulate endothelial transcriptional profile by inhibiting EZH2
Statins protect against the development of atherosclerosis via cholesterol-dependent and independent...
GSE148294: HRP2-DPF3a-BAF complex coordinates histone modification and chromatin remodeling to regulate myogenic gene transcription [RNA-Seq]
Functional crosstalk between histone modifications and chromatin remodeling has emerged as a key reg...