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Sequencing-based assays page 50
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GSE129398: Transcriptome profiling reveals significant changes in the gastric muscularis externa with obesity that partially overlap those that occur with gastroparesis
The goal of the current study was to identify changes in gene expression in the stomach muscularis t...
GSE77129: Wiskott-Aldrich Syndrome-causative mutations disrupt alternative splicing and promote gene networks predisposed to hematologic malignancies
Wiskott-Aldrich syndrome (WAS) is characterized by X-linked thrombocytopenia, eczema, immunodeficien...
GSE121580: Gene expression profiling U87 cells knocking down Glud1 under low glucose treatment
U87 cells (shGlud1 and shNT) were treated with low glucose for 6 hours, then mRNA were extracted for...
GSE121035: RNA-seq of bone marrow tissue of wild type and Elf4 deficient mice after Plasmodium yoelii 17XNL infection
We infected wild type and Elf4 deficient mice with Plasmodium yoelii 17XNL, a non-lethal species, to...
GSE107489: RNA-seq to compare wild type, db/+ and db/db islets
Purpose: RNA seq analysis were to compare and contrast the gene expression profile involved in the d...
GSE112920: IL-27 in vaccine elicited cellular immunity
5000 congenically marked (CD45.1) WT or IL-27R-/- OT1 T cells were transferred into WT B6 hosts (CD4...
GSE117331: Differential gene expression in NPHS2-Cre +/+ mouse glomeruli versus wild-type control
To investigate differential gene expression that might account for the differing glomerular phenotyp...
GSE86813: Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome
By comparing HeLa cells lacking ATF7IP or SETDB1 generated through CRISPR/Cas9-mediated gene disrupt...
GSE116404: Differential RNA-seq analysis of control vs. dnFGFR2b-expressing mouse otocysts reveals targets of FGFR2b signaling at the beginning of inner ear morphogenesis
Induction of dnFGFR2bfor 3 partially overlapping intervals at the early stages of otocyst morphogene...
GSE133684: Blood extracellular vesicle long RNA sequencing of human blood from pancreatic ductal adenocarcinoma (PDAC), chronic pancreatitis (CP) and healthy individuals
Blood samples were collected from all participants in 10-mL EDTA-coated Vacutainer tubes. Plasma was...
GSE110620: REVERSIR platform for the tailored control of GalNAc-siRNA conjugate pharmacology
Primary mouse hepatocytes were treated with 1 nM TTR-siRNA and 10 nM scrambled or TTR-REVERSIR by in...
GSE82260: ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes
Histone acetylation, including acetylated H3K14 (H3K14ac), is generally linked to gene activation. M...
GSE88735: Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq]
During normal or pathological epithelial-to-mesenchymal transition, epithelium-specific gene express...
GSE148721: RNA-seq analysis of WT, CD5 KO, CD6 KO, CD5/CD6 double KO (I) and LAT KO nave CD4+ T cells (II)
Transmembrane adaptors on T cells play crucial roles in TCR signal transduction. Although the TCR-LA...
GSE154081: Comparison of gene expression profiles in hearts exposed to pressure overload (PO) with or without sildenafil treatment in PERK wild type (flx) or PERK cardiac-specific knockout 8cko) mice.
Recently, it is reported that sildenafil suppresses maturation of PO-induced miRNAs. However, the me...
GSE129192: Characterization of Fetal Specific Transcriptional Programs in Thymic Epithelial Cells Identifies Myc as a Critical Determinant of Thymus Size [bulk RNA-Seq]
The thymus is the site of T cell development. Although much is known about the development and diffe...
GSE129362: Transcriptome-wide effect profile of HuR inhibitor KH-3
The purpose of this study is to generate mRNA effect profle of KH-3, an inhibitor of RNA-binding pro...
GSE122886: Transcriptomic analyses of the testicular interstitial cells in murine neonates
Previous studies have established that fetal Leydig cells (FLCs) and adult Leydig cells (ALCs) show ...
GSE117228: Single cell RNA sequencing of primary-isolated erythroid progenitors [BFUE, CFUE, intermediates]
Single cell RNA sequencing of freshly isolated mouse burst forming unit-erythroid (BFU-E) , colony f...
GSE118990: Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation
We performed RNA-Seq and identified the differnetially expressed gene information among WT and ZEB1 ...
GSE116894: RNA-sequencing of Control and TLE3-deficient Beige Adipocytes
Prolonged cold exposure stimulates the recruitment of beige adipocytes within white adipose tissue. ...
GSE138520: Chemical reprogramming of fibroblasts to photoreceptor like cells [RNA-Seq]
Reprogramming of mouse embryonic fibroblasts (MEFs) to photorereceptor like cells by five chemicals....
GSE145383: The role of acid adaptation on transcriptome of breast cancer MCF7 cell line
Acid adaptation is a prominent event in solid tumor evolution and progression. Using RNA sequencing ...
GSE151937: mRNA sequencing of human osteoarthritis chondrocytes treated with or without autotaxin inhibitor
OBJECTIVE: To identify the changes in gene expression elicted by ATX inhibition in human OA primary ...
GSE139179: Differences in tissue populations following hematopoietic stem cell transplantation in Crohns disease patients
Treatment of severely refractory Crohns disease (CD) patients remains a clinical challenge. Recent s...
GSE89385: Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq]
Cyclin dependent kinase 9 (CDK9), a key regulator of transcriptional elongation, has long been consi...
GSE93124: Crizotinib v. DMSO in SW480 cells
SW480 cells were treated with 2uM crizotinib for 72h (versus DMSO) SOURCE: Giulio Superti-Furga CeMM
GSE145180: RNA-seq of GAP43 overexpressed and control SW620 cancer cells
We found GAP43 was significantly downregulated in colorectal cancer. So we reintroduced GAP43 to col...
GSE120691: Differential analysis of gene expression profiles in peripheral blood cells of patients with cervical lesions
Using RNA-sequencing analysis of peripheral blood cells from 11 cervical cancer patients, 21 cervica...
GSE142767: Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors
Breast cancer is a heterogeneous collection of disease arising from the breast with distinct molecul...
GSE121460: Age-related loss of innate immune antimicrobial function of dermal fat is mediated by TGF
Dermal fibroblasts (dFB) resist infection by locally differentiating into adipocytes and producing t...
GSE120715: Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity
We identified a chromatin displacement signature for the bromodomain proteins BRD2, BRD3 and BRD4 at...
GSE120216: Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq
Using RNAseq to identify differentially expressed transcripts between CBFB wild type (WT) and knocko...
GSE119131: RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation
Five million wild type (WT) and CBFB knockout (CBFB_KO) MCF10A cells were subject to ribosomal fract...
GSE116949: Comparison of whole transcript and 3 RNA Sequencing methods
We used two RNA-Seq methods to measure the the global transcription levels in mouse liver cells. The...
GSE119234: Analysis of gene expression differences in lymph node B cell populations of HIV-infected and uninfected controls
This study examines the gene expression profiles of resident lymph node B cell populations in HIV-in...
GSE97032: Alignment of the Transcriptome with Individual Variation in Animals Selectively Bred for High Drinking-In-the-Dark (HDID).
Among animals at risk for excessive ethanol consumption such as the HDID selected lines, there is co...
GSE130021: Single cell RNA-Seq of I2A rhabdoid cell line
We report the application of single-molecule-based sequencing technology for high-throughput profili...
GSE108519: mRNA sequencing to assess RfxCasR and matching shRNA specificity
Matching sets of RfxCasR and shRNAs targeting ANXA4 and B4GALNT1 plus non-targeting (NT) controls we...
GSE107650: Low carbohydrate diet study for non-alcoholic fatty liver disease patients
We performed a short-term dietary intervention with a low-carbohydrate diet in obese subjects with N...
GSE119587: Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model
ER+ PDX (COH-SC31) were exposed to PBDE mixture for 1 weeks. RNA-sequencing analysis was performed t...
GSE99085: Human serum and heparin-free platelet lysate as appropriate xeno-free alternatives for production of human MuStem cell batches
Purpose: The population of muscle-derived stem cells called MuStem cells is presented as promising c...
GSE100684: RNA-Seq of Kaposis sarcoma reveal alterations in glucose and lipid metabolism
Kaposis sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposis sarcoma (KS). In sub...
GSE100356: Transcriptome of neonatal preBtzinger Complex neurons in Dbx1 reporter mice
We sequenced the transcriptome of brainstem interneurons in the specialized respiratory rhythmogenic...
GSE111600: Exploiting Mouse Models to Understand Female Hypersensitivity to Cocaine
Male mice, female mice, ovariectomized female mice given placebo pellets, and ovariectomized female ...
GSE82106: BMP/Taz-Hippo signaling modulates VEGF-mediated angiogenesis
The BMP/TGF-Smad, Notch and VEGF signaling guides formation of endothelial tip and stalk cells. Howe...
GSE104022: Molecular consequences of Dlx3 deletion by tamoxifen inducible K14 Cre in adult mouse epidermis (P42-P46) as determined by RNASeq analysis
DLX3 is a homeodomain transcription factor involved in epidermal and hair follicle differentiation. ...
GSE86430: Directional RNA-Seq on CD4+ T cells collected from children with asthma with/without obesity
We compare the CD4+ T cell transcriptome between obese and normal-weight children with asthma to ide...
GSE106681: GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1)
The estrogen receptor (ER) is expressed in the majority of luminal breast cancers and inhibition of ...
GSE89771: Targeted intron retention and excision for rapid gene regulation in response to neuronal activity
A substantial population of intron retentions are stably maintained in poly-adenylated transcripts a...
GSE108255: Gain of function of the ATXN1-CIC complex drives cerebellar pathology in Spinocerebellar ataxia type 1 (part 2)
We isolated RNA from cerebella dissected from Pcp2-ATXN1[82Q], Pcp2-ATXN1[82Q]V591A;S602D, and wild-...
GSE103945: Differentiation of functional endothelial cells from human iPS cells
Endothelial cell (EC) therapy may promote vascular growth or reendothelization in a variety of disea...
GSE88716: Cell-type-specific Brain Methylomes Profiled via Ultralow-input Microfluidics
Methylomic studies require substantial amounts of DNA samples and this restriction hinders applicati...
GSE85627: Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Mouse]
To better understand transcriptional regulation during human oogenesis and pre-implantation embryoni...
GSE129366: Transnuclear mice reveal a population of Peyers patch iNKT cells that regulate B cell class switching to IgG1
Tissue resident iNKT cells maintain tissue homeostasis and peripheral surveillance against pathogens...
GSE138574: RNA sequencing analysis of HCT116 cells following 24 hours of metabolic recovery from methionine restriction +/- small molecule treatment.
We determined small molecule inhibition of H3K9 HMTs G9a/GLP during methionine restriction results i...
GSE140031: RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs
The aim of the study was to analyze the transcriptional profile of Tregs following CRISPR deletion o...
GSE99399: A transcriptomic study of myogenic differentiation under the overexpression of PPAR by RNA-Seq
To study the cellular and molecular function of PPAR in skeletal muscle differentiation, we have gen...
GSE127896: PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice
Mammalian brain evolved through several transitions between gyrencephaly and lissencephaly. Mechanis...
GSE125239: Autophagy impairments in directly reprogrammed neurons in patients with idiopathic Parkinsons disease
Protein degradation impairment is strongly suspected to play a role in idiopathic Parkinsons disease...
GSE122088: Loss of the FAT1 tumor suppressor promotes resistance to CDK4/6 inhibitors via the Hippo pathway
Loss of FAT1 promotes resistance to CDK4/6 inhibitors. This study was to compare the differential mR...
GSE122230: Genome-wide gene-expression profile of mouse intestinal stem cells/progenitors/Paneth cells
The goal of this project is to generate transcriptome profiling of Lgr5-GFP high intestinal stem cel...
GSE107646: Paired TCR and transcriptome analysis of single T cells characterizes clonally expanded human conventional and unconventional CD8+ T cells
Purpose: Single cell RNAseq has revolutionized our understanding of the heterogeneity of immune syst...
GSE124286: Impact of dietary antigen on gene expression of Peyer's patch T cells
Transcriptional profiling shows that Peyers patch CD4+ T cells from mice kept on dietary antigens ar...
GSE125196: Impact on erythroid progenitor type on erythroid differntiation
We sought to compare mature iRBCs derived from WT or SCA hiPSCs to characterize observable disease p...
GSE129073: Microbiota-driven transcription signatures in lung stroma cells
Commensal bacteria have been shown to influence the reactivity of immune cells in the gut and in oth...
GSE116017: CDK12 Regulates DNA Repair Genes by Suppressing Intronic Polyadenylation
Mutations that attenuate DNA repair by homologous recombination (HR) promote tumorigenesis and sensi...
GSE129387: Gene expression of blood and cerebellum of Mecp2-null and WT male mice
In order to find a relationship between gene expression of blood and brain in Rett Syndrome (RTT), w...
GSE133397: Transcriptomic analysis of resting or activated human CD226- and CD226+ effector memory CD8+ T cell subsets isolated from the peripheral blood of healthy donors.
We recently found that loss of the activating receptor CD226 (DNAM-1) was a critical mechanism affec...
GSE106678: Dissecting cell-type composition and activity-dependent transcriptional state in mammalian brains by massively parallel single-nucleus RNA-Seq
Massively parallel single-cell RNA sequencing can precisely resolve cellular diversity in a high-thr...
GSE106140: Dynamic remodeling of translation programs drives hepatocyte proliferation during liver regeneration
During liver regeneration, most new hepatocytes arise from pre-existing ones; yet, the underlying me...
GSE124259: Dlk1-Mediated Temporal regulation of Notch Signaling is Required for Differentiation of Alveolar Type II to Type I Cells during Lung Repair
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
GSE128696: Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts
Resting NK cells are notoriously difficult to transduce, especially using the VSVG lentivirus pseudo...
GSE139996: The metabolite receptor SUCNR1 in oxidative stress-induced age-related macular degeneration
Murine RPE transcriptomes were generated from SUCNR1 WT and KO mice from both the treated and untrea...
GSE138591: Single myofiber RNA-seq of young and old mice
We developed a method of combining single myofiber isolation with SMART-seq to analyze the whole tra...
GSE154583: Comprehensive analyses of B cell compartments across the human body reveal novel subsets and a gut resident memory phenotype
A comprehensive analysis of B lineage cells in various tissues of multiple healthy organ donors reve...
GSE131840: Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs)
The mechanisms by which oncolytic vaccine strains of measles virus exert their tumor selectivity are...
GSE114099: Transcriptomic Analysis of Wild Type and FOXA2-/- ES-derived Pancreatic Progenitors
Transcriptomic Analysis of Wild Type and FOXA2-/- ES-derived Pancreatic Progenitors SOURCE: Christin...
GSE134090: Gene expression profiles of mESCs
The 24th recoverable satellite of China was designed specifically for experiments on microgravity ph...
GSE128748: RNA-seq analysis of dolastatin 15 treatment in HCT116 cells
Dolastatin 15 is a known tubulin binding agent and shows remarkable differential cytotoxicity agains...
GSE111842: RNA-Seq of Circulating Tumor Cells in Stage II-III Breast Cancer
BACKGROUND: We characterized the whole transcriptome of circulating tumor cells (CTCs) in Stage II-I...
GSE109555: Reconstituting the transcriptome and DNA methylome landscapes of human implantation
Implantation is a milestone event during mammalian embryogenesis. Implantation failure is a nonnegli...
GSE128652: RNA-Seq on wild-type and Ezh2 knock-out invariant natural killer T cells and CD44hi CD4+ T cells
Several subsets of NKT cells have been identified, including IFN-producing NKT1 cells, IL-4-producin...
GSE131854: Spinal cord gene expression profiling of the effect of EHP-101 in EAE model
Spinal cord gene expression profiling of the effect of EHP-101 in EAE model SOURCE: Eduardo Muñoz (f...
GSE144767: Identification of miR-29a-mediated target transcriptome in human pancreatic stellate cells (hPSCs) using RNAseq approach
In this study, we aim to understand the role of miR-29a in in regulating hPSCs. Identification of th...
GSE147998: High-throughput sequencing of inguinal white adipose tissue fractions from female C57BL/6 Kdm5c+/+ and Kdm5c+/ mice
RNA sequencing was performed on white adipose tissue fractions to determine the effects of having on...
GSE131998: RNAseq of Extracellular vesicle RNAs and cellular RNAs from HPASMCs with or without TGF-b1 or BMP4 treatment
Excessive TGF- signalling has been shown to underlie pulmonary hypertension (PAH). Human pulmonary a...
GSE112991: Transcriptome profiling of Cryptosporidium parvum infected lung and intestinal organoids
Purpose: Transcriptome profiling of Crytosporidiumparvum infected lung and small intestinal organoid...
GSE108546: Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s
CD34+ cord blood hematopoietic progenitors were expanded in vitro as previously described (Balan et ...
GSE107984: The arginine methyltransferase CARM1 represses p300ACTCREMt axis and is required for spermiogenesis
DEGs in the round and elongating spermatids between the WT and Carm1-null testis. SOURCE: Jianqiang ...
GSE104090: Migrating interneuron transcriptomes in Wt and CCP1 cKO mouse embryos
CCP1 is a deglutamylase responsible for protranslational modification of proteins. CCP1 cKO interneu...
GSE114708: Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells
ABL cells (derivative of LNCaP) were treated with 100M UK5099 or vehicle (control) for 72 hours, at ...
GSE108315: De novo formation of a functional biliary system by TGF-mediated hepatocyte transdifferentiation
We observed de novo formation of peripheral bile ducts by transdifferentiation of hepatocytes in mic...
GSE124658: PTEN modulates gene transcription by redistributing genome-wide RNA polymerase II occupancy [RNA-seq]
Control of gene expression is one of the most complex yet continuous physiological processes impacti...
GSE106867: Identification of immune-activated Hematopoietic Stem Cells
We utilized our transgenic Fgd5-mCherry mouse to sort and RNAseq for HSCs under acute immune activat...
GSE107323: Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease
To understand whether hepatic cells use autophagy to defend against Cu toxicity in WD, we employed A...
GSE104462: Genome-wide analysis of ferroptosis related genes in liver cancer cells.
To seek ferroptosis related genes in liver cancer cells, we treated HepG2 cells using ferroptosis in...
GSE130081: Gene expression changes in Neil1, Neil2 and Apex1 single knockout mouse embryonic stem cells prior and during embryoid body differentiation
The bifunctional DNA glycosylases/AP lyases NEIL1 and NEIL2 excise oxidative base damages, but can a...
GSE131338: Consequences of decreased TNAP activity during osteogenic differentiation of periodontal ligament cells a new model for dental defects in hypophosphatasia
The effects of TNAP inhibition with levamisole during osteogenic differentiation were analyzed in pr...
GSE115348: Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline [cell populations]
Diminishing potential to replace damaged tissues is a hallmark for ageing of somatic stem cells, but...