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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Facioscapulohumeral dystrophy (FSHD; OMIM #158900, #158901) is caused by mis-expression of the DUX4 ...
RNA preparation for sequencing was performed as described in (Fiorenza et al., 2016). Hippocampi der...
The KZFP/KAP1 (KRAB zinc finger proteins/KRAB-associated protein 1) system plays a central role in t...
RNA profile of EpCAM+ sorted cells freshly isolated from healthy liver of adult mice was performed ...
Enhanced RAF/MEK/ERK signaling plays an obligatory role in many different types of cancer. Although ...
In order to identify SOX4- and TGF-beta dependent genes, human mammary epithelial cells (HMLEs) were...
Intermediary metabolism generates substrates for covalent modification of chromatin, enabling potent...
To assess the transcriptomic response of human lung fibroblast to TGF-, human MRC5 pulmonary fibrobl...
Dietary restriction is a well-known model to induce longevity across a variety of model organisms ra...
Purpose : to decipher the role a newly identified protein, RNF219, we performed a pull down of this ...
The histone deacetylase HDAC3 is a critical mediator of hepatic lipid metabolism, and liver-specific...
Molecular heterogeneity among spiral ganglion neurons (SGNs) in the mouse cochlea was investigated i...
We report that colonic lamina propria anti-inflammatory macrophages from Il10rb-/- (KO) mice at 12 w...
Research conducted using the novel approach of Next Generation Sequencing to determine the different...
It has long been recognized that anatomic location is an important feature for defining distinct sub...
Purpose: Next-generation sequencing (NGS) has been utilized for systems-based analysis of all liver ...
Diseases caused by gene haploinsufficiency in humans commonly lack a phenotype in mice heterozygous ...
We report a novel single-cell total RNA-seq method, RamDA-seq, by combining a novel reverse transcri...
Mycobacterium tuberculosis (Mtb) displayed cording phenotypes during intracellular infection. RNA-Se...
Several inherited arrhythmias primarily affect the right ventricle, including Brugada syndrome and a...
Purpose: The goal of this study was compare the transcriptional profile of CD34+ AML stem/progenitor...
Bone marrow Hdc-GFPhi and Hdc-GFPlo HSPC (SLAM-LSK, Lin-c-kit+Sca-1+CD150+CD48-) HSCs were isolated...
In this study, we demonstrated the synergistic effect of the mechlorethamine-romidepsin combination ...
The molecular chaperone heat shock protein 90 (HSP90) is thought to buffer genetic variation uncoupl...
Purpose: Stanniocalcin 1 (STC1) is a secreted glycoprotein expressed in mesenchymal stroma cells (MS...
Mammalian sperm and oocytes have different epigenetic landscapes and are organized in different fash...
We have used RNA-seq to identify transcripts expressed in human islets harboring beta cells transduc...
ATAC-seq, RNA-seq and ChIP-seq in induced TSC and PSC 72 hours past Doxycyclin induction SOURCE: Tom...
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that leads to the loss of m...
Pharmacological and functional genomic screens play an essential role in the discovery and character...
Cardiac fibrosis is the final common pathology in heart disease. Here we establish an integrated ima...
Purpose: Next-generation sequencing (NGS) has become a powerful microscope to study cell models of H...
We demonstrate that Slfn2 interacts with protein phosphatase 6 regulatory subunit 1 (PPP6R1), leadin...
The heat shock response (HSR) is a mechanism to cope with proteotoxic stress by inducing the express...
IDH1-R132H is expressed in Low Grade Glioma (LGG) in combination with mutation in ATRX and TP53 gene...
In order to study the green anole dosage compensation mechanism we generated strand-specific RNA-seq...
Pluripotent stem cells (PSCs) exist in multiple stable states, each with specific cellular propertie...
In embryonic stem cells (ESCs), bivalency characterizes the chromatin state of developmental gene pr...
We report the transcriptional difference of L2hgdh gene knock out mice brain with wild type control ...
Expression profile of human GEP-NET tumors, including 113 fresh frozen biopsies of primary and metas...
Infant B-acute lymphoblastic leukemias (B-ALL) that harbor MLL-AF4 rearrangements are associated wit...
In order to find out circular RNAs profiles in human bladder cancer tissues and normal bladder tissu...
Recent efforts have uncovered immense transcriptional and ontogenetic diversity among tissue-residen...
The aim of the dataset was to demonstrate that the gene expression profile of CD11bhiF4/80low TAMs a...
IL-17 is a key cytokine important for defense against infection and plays a critical role in inflamm...
High throughput sequencing of poly-A RNA SOURCE: Markus Schulze (markus.schulze@ukr.de) - Markus Rie...
We show that monocyte development is accompanied by stepwise RNA expression changes and that Ly6C+ m...
Analysis of the transcriptional changes in the forebrain resulting from the loss of ultraconserved e...
Using RNAseq, we compared the mRNA profiles of microglia in wild type or microglia-specific A20 knoc...
Atherosclerotic plaque rupture with subsequent embolic events is a major cause of sudden death from ...
This study explores the underlying pathogenic mechanisms of congenital intrinsic obstruction of the ...
Recent studies have uncovered that activation-induced cytidine deaminase (AID) and ten-eleven-transl...
Human monocyte-derived macrophages (MDM) serve as a model for resident alveolar macrophages (AM) in ...
Chemerin is a leukocyte chemoattractant and an adipokine. Overexpression of chemerin by tumor cells ...
Activation-induced cytidine deaminase (AID) mediates class switching by binding to a small fraction ...
Single cell sequencing of Hsd11b2-expressing neurons in the NTS from mice fed standard chow or low s...
Analysis of transcriptome from AR-deleted CARN-derived lines (ADCA) and controls, AR-positive CARN-d...
Successful host defense against pathogens requires innate immune recognition of the correct pathogen...
Hematogenous metastasis is initiated by a subset of circulating tumor cells (CTCs) shed from primary...
During chronic infection memory T cells acquire a unique phenotype and become dependent on different...
We aim to profile the dynamic changes of gene expression dynamics during cortical neuron differentia...
Concerted efforts over past decades have established a thorough understanding of the canonical somat...
Single-cell RNA-seq analysis of pre- and postnatal mouse endolymphatic sac demonstrates two types of...
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol SOURCE: Eduardo Muñoz (fi1mub...
Pelizaeus-Merzbacher disease (PMD) is a pediatric disease of myelin in the central nervous system an...
To understand the role of Ezh2 in B cell differentiation B cells were stimulated ex vivo with LPS, I...
The goal of this study is to evaluate transcriptome profiles that accompany mouse radial glial cells...
Transcriptome of si-RNA transfected NOK cells and adenovirus-transduced HEK cells SOURCE: Maria,Ire...
The activation of Liver X Receptor (LXR) promotes cholesterol efflux and repression of inflammatory ...
We use RNA-sequencing to measure global transcription in uteri of young and aged (~1yr old) C57BL/6 ...
mRNA expression in two different cell lines (DEV and G401) and two conditions (CLOFILIUM and DMSO) w...
X chromosome inactivation (XCI) compensates for differences in X-chromosome number between male and ...
Purpose: To clarify the biological processes underlying variation in disease location and antimicro...
Background: In human malaria, parasites of the genus Plasmodium elicit expansion of atypical memory ...
The goals of this study are to generate inflammation-sensitive astrocytes from human induced pluripo...
Here we profile nascent transcription, RNA polymerase III occupancy, chromatin accessibility, and H3...
RNA-Sequencing of entorhinal cortex and primary visual cortex from 14-15 month old APOE3/4 vs. APOE3...
The RNA binding protein Celf1 regulates alternative splicing in the nucleus and mRNA stability and t...
Bulk RNA-seq, and single cell RNA-Seq using inDrops methodology, were used to compare two population...
By high-throughput RNA-seq of heavy polysomal fractions, we report that rpS6 knockin mice, in which ...
The genomic repertoire of enhancers and promoters that control the transcriptional output of termina...
Three kinds of TSCs with different genotype of mouse Tet2 including Tet2+/-, Tet2-/-and wild-type TS...
mTORC2 senses nutrients and coordinates substrate metabolism and macromolecule synthesis program wit...
Adult parotid gland RNA-seq libraries and embryonic submandibular gland RNA-seq libraries were creat...
Background: Low-caloric diet (LCD) reduces fat mass excess, improves insulin sensitivity, and alters...
Dietary restriction (DR) appears to create a cellular memory, which persists even after DR is discon...
In order to identify the processes altered in T regulatory cells (Treg) by Zoledronic acid (ZA), we ...
Growing evidence implicates the importance of glia, particularly astrocytes, in neurological and psy...
We recently reported the discovery of a small molecule inhibitor, AI-10-49 which can specially inhib...
The differential gene expression of human cardiomyocytes induced by kinase inhibitors sorafenib and ...
Here we show that Libramed has remarkable, beneficial effects on daily metabolism of an animal model...
Transplanting vascular endothelial cells (ECs) to support metabolism and express regenerative paracr...
The primary objective of the study was to investigate the uncoupling protein-1 (UCP1) associated fea...
The ability to compare the abundance of one RNA molecule to another is a crucial step for understand...
CHD8, encoding a chromatin remodeling protein, is one of the most frequently mutated genes in autism...
Proteogenomics, i.e. comprehensive integration of genomics and proteomics data, is a powerful approa...
We performed ChIP-seq of p63 in ME-180 cell line and RNA-seq of knockdown and overexpression of p63 ...
Understanding the mechanism of resistance of certain genes to reactivation will help improving the s...
We employed marker-free single-cell RNA-Seq to characterize comprehensive transcriptional profiles o...
We have examined the role of the replication stress protein Etaa1 in mouse effector T cell expansio...