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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Gene expression profiles of specific neuronal populations might explain differential vulnerability t...
Understanding the unique mechanisms of human oogenesis necessitates the development of an in vitro s...
As our results suggested that metformin acts to limit mitochondrial ROS and calcium-mediated activat...
Introduction: The mechanisms governing synaptonuclear transport, and the transcriptional pathways th...
Hepatocellular carcinoma (HCC) represents the fifth most common form of cancer worldwide and carries...
We sequenced mouse incisor mRNA from 6 mice (3 WT and 3 mutant) to compare their gene expression pro...
Mammalian brains are highly conserved at both the neuroanatomical and gene expression levels. Howeve...
Comparison of transcriptome between control and NIK-stabilized leukemia stem cells SOURCE: Thomas,B,...
Cell surface markers of adult hematopoietic stem cells (HSCs) are well established, but fewer marker...
Persistent microglia activation is associated with the production and secretion of various pro-infla...
We repoted the Glioblastoma stem cells(GSCs) infected by two strains of ZIKA virus, the Brazil and D...
This study aimed to quantify and compare the mRNA abundance of all major XPGs in liver and intestine...
Goal of this study was to examine gene expression changes upon conditional deletion of beta-catenin ...
Purpose: To compare the transcriptome of wild type and Mesp1Cre+/Dgcr8-/- embryonic heart at embryo...
Objective: To evalute the role of Ezh2 in chondrocyte differentiation.; Method: Ezh2 was inactivated...
To understand global gene expression patterns of mouse livers upon dual-oncogene transfection, RNA s...
CHAF1B is the p60 subunit of the chromatin assembly factor (CAF1) complex, which is responsible for ...
We investigated transcriptomic effects of a Smarca4 ATPase mutant observed in primary tumors and can...
Our study reports strain specific expression and abensce of sexual dimorphic expression in mouse vom...
The lineage of the horizontal basal cells (HBC) stem cells and their descendants from the olfactory ...
Human pluripotent stem cells (H9s) were differentiated into endothelial cells (ECs), neural stem cel...
Small-molecule based lineage reprogramming has newly emerged as a promising approach for generating ...
We present three mouse models of kidney cancer that recapitulate the genomic alterations found in hu...
An integrated RNA sequencing transcriptomic and quantitative proteomic analysis were employed to sys...
A fully developed initial segment, the most proximal region of the epididymis, is important for male...
Human T cells coordinate adaptive immunity by localization in diverse tissue sites, though blood T c...
We performed gene expression profiling of alveolar macrophages from mice that were intratracheally i...
Many studies have been launched to investigate cellular and molecular regulation regarding human neu...
Note: this project is a combination of the data deposited here in GEO and data made available by HD...
Neutrophils are responsible for the first line of defense against invading pathogens. Their nuclei a...
FET family RNA binding proteins are implicated in cancer and neurological disorders and yet their bi...
Analysis of metabolism related gene expression in liver and adipose tissues from MKRN1 knockout mice...
To determine the differentially expressed genes between these subsets and identify the core human in...
Integration of index sorting and single cell functional assays allowed identification of novel haema...
Interleukin-10 is a dimeric cytokine with potent anti-inflammatory and anti-cancer activities. Despi...
Human pluripotent stem cells (hPSCs) are an important player in disease modeling and regenerative me...
Purpose: Transport processes in the renal collecting duct are responsible for precise regulation of ...
Integrated Stress Response (ISR) is a homeostatic mechanism induced by endoplasmic reticulum (ER) st...
TP53 mutations occur in approximately 50% of all human tumors with increased frequency in aggressive...
The obesity epidemic is a significant global health issue. Improved understanding of the mechanisms ...
Using RNAseq we describe transcriptional changes downstream of liver-specific knockout of RNaseH1, i...
Latent pancreatic cancer metastases are created when T cells select disseminated cancer cells in whi...
RNA-seq evaluation of post-mortem human cerebelllum from 33 patients with diagnosed Essential tremor...
we report here that Smad5 acts as a pHi messenger and maintains bioenergetic homeostasis of a cell b...
Dystonia is characterized by involuntary muscle contractions. Its many forms are genetically, phenot...
We monitored the transcription changes associated with loss of BRG1, BRM, or both combined I HepG2 c...
human leukemia cells treated with vitamin C for 12 and 72hrs and mouse hematopoietic progenitor cell...
Purposes: (1) compare the SUMO chromatin landscape between mouse embryonic fibroblasts (MEFs) and em...
The goal of this study is to identify the differentially expressed genes in Gdf9-Cre mediated Mtor o...
Poised enhancers marked by H3K27me3 in pluripotent cells were previously proposed to facilitate the ...
To assess the effect of different forms of TL1A within different organs of the mouse we generated 2 ...
Whole blood transcriptional signatures distinguishing patients with active tuberculosis from asympto...
To elucidate the molecular bases for the infertile phenotype of Zmym3 KO mice at the mRNA expression...
Molecular definition of an RNA-mediated mechanism that stabilizes association of the Suv39h enzymes ...
RNA sequencing of tissue samples taken from pediatric cancer patients of varying disease type. Patie...
Cohesin extrusion is thought to play a central role in establishing the architecture of mammalian ge...
To investigate how pleiotropic the impact of p53 loss is on cellular function, generated isogenic, p...
Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive Schwann cell (SC)-lineage de...
C5aR1, a receptor for the complement activation proinflammatory fragment, C5a, is primarily expresse...
Long noncoding RNAs (lncRNAs) play important roles in various biological processes; however, few hav...
Natural killer (NK) cells contribute to the development of obesity-associated insulin resistance. We...
Host factors in the intestine, such as mucus secretion, play an important role in selecting for the ...
The goal of this study is to compare downstream genes of Sema6D signaling in both M1 and M2 macropha...
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes...
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human malignancies, owing in part t...
We explored the ability of External RNA Control Consortium (ERCC) standards to detect technical bias...
Lineage plasticity is a major mechanism driving prostate cancer progression and antiandrogen therapy...
We performed RNA-seq with dissected control and Lef1 mutant hypothalami from 3 days post-fertilizati...
Survival of primary CLL cells is mediated by mesenchimal stromal cells in vitro. The goal of this st...
Purpose: To asses changes in gene expression profiles from the P30 wild type littermate control olfa...
Poised enhancers marked by H3K27me3 in pluripotent cells were previously proposed to facilitate the ...
BACKGROUND: Targeted therapies specifically act by blocking the activity of proteins that are encode...
Our group has recently shown induction of antigen-specific T cell tolerance through targeting antige...
In response to UVB irradiation, human keratinocytes transiently block cell cycle progression to allo...
To tease apart the downstream signaling triggered by the Asic3-mediated ion current, RNA-sequencing ...
In immunosurveillance, bone-derived immune cells infiltrate the tumor and secrete inflammatory cytok...
Chromatin modifications and the promoter associated epigenome are thought to be important for the re...
Insulin activation of phosphoinositol 3-kinase (PI3 kinase) regulates metabolism, including the tran...
Alternative polyadenylation (APA) regulates mRNA translation, stability, and protein localization. H...
Here, we show that embryonic stem cells (ESCs) and muscle stem cells contain high levels of nuclear ...
We identified a novel N1-methyladenosine (m1A) modification in tRNALys with distinct effects on the ...
Control and 2G8-treated MiaPaca-2 and Colo375 xenografts were subjected to RNA-seq analysis for mous...
The regulation of final nephron number in the kidney is poorly understood. However, cessation of nep...
The monoallelic expression of olfactory receptor (OR) genes is governed by the formation of large do...
To investigate the impact of CD4+ T cells on tumor vasculature, we performed transcriptome profiling...
Microglia play essential roles in central nervous system (CNS) homeostasis and influence diverse asp...
Metabolic reprogramming dictates the fate and function of stimulated T cells, yet these pathways can...
Adult women are twice as likely as men to suffer from affective and anxiety disorders, although the ...
The experiment aimed at determing the influence of mast cell deficiency on the transcriptome of skin...
O-GlcNAcylation is the modification of serine and threonine residues with beta-N-acetylglucosamine (...
We report high-throughput profiling of gene expression from murine primary macrophages. We profile m...
GM-CSF positve CD4 cells are found at sites of inflammation. The purpose of this study was to unders...
Protein deacetylase SIRT7 is significantly downregulated in lung metastases of human patient and mou...
DTP heterochromatin in genomic repeat regions protects the population from drug-induced death. SOURC...
We tested various architectures of artificial transcription factors (ATFs) in HEK293 cells to test t...
Mechanisms by which IFN- activates genes to promote macrophage activation are well studied, but litt...
Pdgfra+ oligodendrocyte precursor cells (OPCs) arise in distinct specification waves during embryo- ...
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes...
Recent studies have shown that group 2 innate lymphoid cells (ILC2s) can drive eosinophilic airway i...
Transcriptional events leading to outgrowth of neuronal axons have been intensively studied, but the...