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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
DNA methylation plays essential roles in mammalian development. During post-implantation development...
RNA-seq analysis of BJ cells overexpressing RasV12 and escaping senescence SOURCE: romain forey (rom...
Endothelization of the luminal surface of vascular grafts is required for their long-term functionin...
The incidence of colorectal cancer (CRC) is increased in patients afflicted by inflammatory bowel di...
We identified the first Spt5-Pol II inhibitors (SPIs). SPIs faithfully reproduced Spt5 knockdown eff...
Acute lymphoblastic leukemia is marked by aberrant transcriptional features that alter cell differen...
We collected triplicate samples at day 15 under serum condition, generated single cell suspensions a...
Brain metastasis (BrM) represents a challenging clinical issue. The most common treatment options ar...
We used RNA sequencing to study gene expression in lymph node derived DCs from anaphylactic mice sen...
IL-2R signaling is essential for regulatory T cell (Treg) function. However, the precise contributio...
The genes Ift88 and Dzip1 are critical for primary cilium biogenesis, the objective this study was t...
Sex is a key modifier of neurological disease outcomes. Microglia are implicated in neurological dis...
Two healthy iPSC lines (78 and 273) were differentiated into ECs. iPSC-ECs were then treated with e-...
Non-transformed LMP1 expressing mouse B cells or mouse LMP1 lymphomas were analysed by RNA-sequenci...
We report differences in gene expression between WT and Sin3B KO T98G cells throughout the cell cycl...
Although mutations in the RNA splicing factor SF3B1 are frequently observed in multiple human cancer...
This study examines the global transcriptomic profiles in peripheral blood of Papua New Guinea newbo...
Peroxisome Proliferator-Activated Receptor-gamma (PPARG) is a nuclear hormone receptor that was orig...
RNA binding proteins (RBPs) regulate gene expression through several post-transcriptional mechanisms...
The hematopoietic stem cell (HSC) compartment includes lymphoid biased (Ly-HSCs) and myeloid biased ...
The host immune response against an infection requires the coordinated action of many diverse cell s...
Contrasting with fish or amphibian, retinal regeneration from Mller glial cells is largely limited i...
Using next generation sequencing, we report transcripts that are differentially associated in the mo...
Exposure to estrogen and its mimics during menopausal transition is thought to modify the structure ...
Disrupting central estrogen signaling exposes a powerful sex-dependent brain-to-bone axis in female ...
The generation of terminally differentiated cell lineages during organogenesis requires multiple, co...
The goals of this study are to compare MEFs transcriptome profiling (RNA-seq) from Lztr1 +/+ and +/...
We identified four transcriptional factors, Runx2, Osx, Dlx5, and ATF4, that rapidly and efficiently...
To identify novel transcripts originating from orphan CGIs we isolated RNA from undifferentiated emb...
RNAseq of samples to identify changes in gene expression upon SRSF2 mutation SOURCE: Diana,HP,Low (d...
Haematopoietic stem cells (HSCs) reside in bone marrow (BM) niches where they are maintained to repl...
To study the mRNA modulating network and different expressed mRNA lists in MHCC-97H-SH-UCK2 cells, w...
KRAB-zinc finger proteins (KZFPs) represent one of the largest families of DNA binding proteins in v...
Purpose: Parturition is delayed by approximately 12 hours in transgenic mice expressing human corti...
In this study, we differentiated mouse ESCs via 3D aggregates called embryoid bodies in presence of ...
Regulatory T (Treg) cells maintain immune tolerance through the action of the master regulator FOXP...
We report the comparative investigation of gene expression profiles between genetic inactivation AXL...
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are associated with loss of nu...
The mammalian BRG1-associated factors (BAF) complex is a multi-subunit chromatin remodeling complex ...
Purpose: To understand the molecular mechanisms underlying NPM1c-mediated tumorigenesis by comparing...
Epicardial cells are progenitors giving rise to the majority of cardiac fibroblasts, coronary smooth...
Human endogenous retroviruses (HERV) are relics of ancient retroviral infections in our genome. Most...
Expression of co-inhibitory receptors, such as CTLA-4 and PD-1, on effector T cells is a key mechani...
RNA-seq analysis of gastrocnemius of control and Il13-deficient mice after 5-weeks of endurance exer...
Transcriptomic profiling of second heart field progenitor cells deficient for Hoxb1 in mouse embryos...
Purpose: The goal of this study is to investigate the role of NCoR1 in protecting colon from ulcerat...
This analysis represents the first comprehensive sampling of germ cells in the developing testis ove...
The canonical Wnt signaling pathway has been demonstrated as a critical role in the self-renewal, pr...
Hematopoietic stem cells (HSC) sustain hematopoiesis throughout life, exiting dormancy to replenish ...
We sought to determine whether Ldh activity in SCC tumors is a marker of the cell type from which th...
Intrauterine growth restriction (IUGR) affects up to 10% of pregnancies and often results in short- ...
Analyses of the effect of CRISPR/CAS9 mediated knock out of the EMT-transcription factor SNAI2 on th...
Aim: Identification of long noncoding RNAs using transcriptional analysis of e15.5 mouse embryonic p...
The objective of this study was to understand the mechanisms by which electrical stimulation in vivo...
To explore BML-260 how to increase thermogenesis, we treated brown adipocytes with BML-260 and DMSO ...
Suv39h1wt or mut mRNA was injected into the zygote and cultured for the indicated timepoints SOURCE:...
Obesity is a risk factor for multiple diseases, including diabetes, cardiovascular disease, and canc...
Here, we show that short term HFD feeding did not change the cardiac function in normal (Con) and in...
We report XBP1 activation and regulation of pro-inflammatory signaling in astrocytes, microglia, and...
The modulation of TGFb activity is critical for the specification of mesendoderm tissue progenitors ...
Human astrocytes can be efficiently reprogrammed into functional neurons in culture by the addition ...
We use single-cell RNA-seq to determine distinct selection phenotypes of 2 rare thymic Treg cell pro...
To understand the effect of LncMyod knockdown on cultured satellite cells, we isolated satellite cel...
Transcriptome analysis comparing livers of 10 month old MANFHet mice and WT littermates revealed the...
Insufficient repair of DNA lesions results in the acquisition of somatic mutations and displays the ...
Defining cellular and molecular identities within the kidney is necessary to understand its organiza...
We set out to determine if prostate epithelial cell-types exhibited age-related differences in their...
We performed rigorous ribosome profiling in FMCD mouse models with human MTOR point mutations. By ob...
Nrn1-/- and Nrn1+/- Thy1.1+ OTII cells were cotransferred with wt Treg cell into TCRa-/- hosts and s...
The inactive X chromosome (Xi) is folded in a stepwise process into a compartment-less structure. He...
To perform mRNA expression analysis through deep sequencing, RNA was isolated from prostate mice tre...
In this study we compared transcriptome profiling (RNA-seq) in wild type vs. ACE overexpressiong Tg-...
Epidemiologic studies demonstrate that women from cultures that consume high levels of dietary soy h...
Purpose: To characterize the estrogen receptor (ESR1)-dependent transcriptome of neurons in the arc...
The purpose of this study is to compare transcriptional profiles of non-small-cell lung cancer betwe...
The genomes of mammalian neurons contain uniquely high levels of non-CG DNA methylation that can be ...
The role of mitochondria dynamics and its molecular regulators remains largely unknown during nave-t...
The mammalian liver possesses a remarkable regenerative ability. 1) The 'oval cell' response emanate...
Expression analysis of mouse sinoatrial nodes and working cardiomyocytes SOURCE: Vincent,M.,Christof...
Reprogramming somatic cells to pluripotency represents a paradigm for cell fate determination. A bin...
We performed RNA-seq analsysis of polA transcripts in Kelly and Kelly E9 resistant (E9R) cells treat...
RNA sequencing of mouse islets from mice containing a pancreas-specific deletion of Glis3, and contr...
Understanding how RNA-binding proteins interact with RNA transcripts for splicing regulation is fund...
Hematogenous metastasis is initiated by a subset of circulating tumor cells (CTCs) shed from primary...
The project used next generation sequencing for RNA-seq analysis, to identify transcriptome changes ...
We report RNA sequencing data from tibialis anterior muscles of 4 month old male wild type C57Bl/6 m...
Neurons were dissociated and purified from adult (~3 months) mouse brains. We used four strains with...
Persistent exposure to high levels of antigen results in the progressive exhaustion of T cells and h...
NR4A nuclear receptors are tumor suppressors of acute myeloid leukemia (AML) that are silenced in AM...
The cytokine transforming growth factor-B (TGF-B) regulates development and homeostasis of several t...
Epigenetic regulators are commonly mutated in cancer. Activating mutations and overexpression of the...
ARID1A and PI3-Kinase (PI3K) pathway alterations are common in neoplasms originating from the uterin...
Regulatory T (Treg) cells maintain self-tolerance in lymphoid tissues, and specialized Treg cells ac...
During embryogenesis, enhancer-promoter interactions control gene transcriptional activation. These ...
RNA-Seq of immortalized Stat5a-/-, Stat5b-/-, and wildtype BCR/ABLp185+ cell lines was used to ident...
RNA-Seq was performed to screen transcripts in whole lyastes or mitoplast fraction prepared from you...
LMNA mutation caused reduced expression of IGFBP5 in patient samples SOURCE: Trina,M.,Norden-Krichma...
Neural cell adhesion molecule 1 (NCAM1; also known as CD56) is expressed in up to 20% of acute myelo...
Malignancies arising from mutation of tumor suppressor genes display an unexplained tissue proclivit...
Complex genetic inheritance is thought to underlie many human diseases, yet experimental proof of th...