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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
To identify novel genes and adaptations induced by resveratrol preconditioning that could promote lo...
Of the four primary subgroups of medulloblastoma, the most frequent cytogenetic abnormality, i17q, d...
Endoderm differentiation is a critical step leading to development of the gastrointestinal system. ...
Idenrify the function of NSP1 SOURCE: Zhou Shen (szhou1314@webmail.hzau.edu.cn) - Huazhong agricult...
The KDM6 histone demethylases (UTX/KDM6A and JMJD3/KDM6B) mediate removal of repressive histone H3K2...
loss of Hmgb2 in vivo in mouse liver largely prevented CCl4-induced liver fibrosis. The goal of the ...
Analysis of gene expression by astrocytes or non-astrocyte cells in spinal cord injury (SCI) lesions...
Purpose: The goals of this study were to identify preferential gene expression signatures that are u...
Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation of abnorm...
The microRNA (miRNA) dependent regulation of gene expression confers robustness to cellular phenotyp...
MLL4 is an essential subunit of the H3K4 methylation complexes. We report that Mll4 deficiency compr...
In this study we isolated and cultured neural progenitor cells (NPCs) from human fetal brain collect...
For the first time, we here characterize the transcriptional signature of satellite glial cells (SGC...
Conversion of fibroblasts to functional cardiomyocytes represents a potential approach for restoring...
We identified four major temporal patterns of Calcineurin (Cn)-dependent gene expression in differen...
We have utilized induced pluripotent stem cells (iPSCs) derived from Huntingtons disease patients (H...
Mouse glioblastomas were induced by lentiviral vector expressing HrasG12V and shRNA against p53. Tum...
Alas2 gene encodes the rate-limiting enzyme in heme biosynthesis. CRISPR/Cas9-mediated ablation of t...
In mammals, DNA methylation occurs mainly at 5mC of CpG dinucleotides. The methylation on the promot...
Within the bone marrow, hematopoietic stem cells differentiate and give rise to diverse blood cell t...
RNA-seq was performed after YB5 cells were treated with 1uM decitabine, and MCF7 cells were treated ...
Changes in gene regulation have long been known to play important roles in both innate and adaptive ...
PI3K/mTOR inhibition alters gene transcription signatures involved in metabolism and cell cycle cont...
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
Following genital HSV-1 infection in mice, virus spreads to and infects the sensory neurons of the d...
We performed high throughput RNA-sequencing on blood and lymphatic HMVECs to identify differences in...
An X-chromosome exome sequencing analysis identified a mutation in O-GlcNAc transferase (OGT) (pL254...
We implemented transcriptomic analyses of hADSCs treated with metformin 6 days SOURCE: Hailiang Liu ...
We generated maternal and paternal mouse models with Yap1-deletion, and elucidated the function of m...
This study first reveals that MYT1 is a potential oncogene in neuroblastoma, which is significantly ...
Human genetic studies have identified the neuronal RNA binding protein, Rbfox1, as a candidate gene ...
We did the transcriptome analysis of peripheral blood mononuclear cells of LADA patients and healthy...
The Core Binding Factor (CBF) protein RUNX1 is a master regulator of definitive hematopoiesis, cruci...
Introduction of Hermansky-Pudlak Syndrome-associated mutations with CRISPR/Cas9 genome editing, allo...
Somatic hypermutation (SHM) and class switch recombination (CSR) increase the affinity and diversify...
Distinct subtypes of intracortically-projecting neurons (ICPN) are present in all layers, allowing p...
Consumption of a protein containing meal by a fasted animal promotes protein accretion in skeletal m...
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that is characterized ...
The study aims to determine SPT effect on the CRPC growth and molecular alterations using LuCaP PDX ...
In proliferating cells, where most Polycomb repressive complex 2 (PRC2) studies have been performed,...
RNA-seq of Ro60-null GM12878 cell lines in order to determine the gene expression changes resulting ...
Here we identify the activator protein-1 (AP-1) factor JunB as an essential regulator of Th17 cell i...
Eumyc lymphoma was inoculated i.v. into C57BL/6J mice. Spleens were harvested from healthy or Emyc l...
Trithorax group (TrxG) and Polycomb group (PcG) proteins are two mutually antagonistic chromatin mod...
Prevention and treatment options for hepatocellular carcinoma (HCC) are presently limited, underscor...
YY1 is a ubiquitously expressed transcription factor that has been demonstrated to be essential for ...
OT-I CD8 T cell transcriptome of cells isolated from Spleen, IV+ brain, and IV- brain of DCLM immuni...
We performed RNA-sequencing in c-Kit+ cells that were infected with retroviruses expressing shRNAs f...
Here we report the identification of a mutant allele of the Ing5 gene, also known as Inhibitor of Gr...
Long RNA-seq analysis on cellular and extracellular samples from a KRAS mutant colorectal cancer cel...
Background: The muscularis externa (ME) of the adult intestine consists of two layers of visceral sm...
Melanoma is a highly aggressive cancer with increasing incidence rates and a poor survival, particul...
Two cell lines (HT55 and SW948) were found responsive to itraconazole treatment. To identify the mo...
Plasmacytoid dendritic cells (pDC) specialize in type I interferon production to coordinate innate a...
Cellular heterogeneity can emerge from the expression of only one parental allele, however it has re...
1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) plays an integral role in calcium homeostasis in higher organ...
RNA-seq of bone marrow CD34+ cells of myelodysplastic syndrome (MDS) and chronic myelomonocytic leuk...
Innate lymphoid cells (ILCs) play key roles in host defense, barrier integrity, and homeostasis, an...
We introduce an in vivo imaging approach that allows us to temporally and spatially resolve the evol...
Recent advances in single-cell RNAseq technologies are enabling new cell type classifications. For n...
The sequential activation of distinct developmental gene networks governs the ultimate identity of a...
Purpose: Seek for differential gene expression in vemurafenib-resistant A375 tumors vs. untreated co...
High-throughput sequencing analysis of transcriptome from LPS-activated B cells from Lymph node of Z...
Purpose: Determine the function of lncBATE10 in brown and white adipocyte differentiation; Methods: ...
Naive spleens as well as naive and LPS-treated dendritic cells from wildtype and GPR34-/- mice were ...
Our study demonstrated that e-cigarettes, both with and without nicotine, induced sex-dependent gene...
A complex damage signal promotes co-localization of NFB and Smad3 at Rev-erb-sensitive enhancers and...
We report RNA sequencing of single olfactory neurons from mouse olfactory epithelium in developmenta...
The goals of this study aim to reveal functional and phenotypic diversity of Spleenic Macrophage sub...
B7S1 negatively regulates T cells and its expression correlates with poor prognosis of cancer patien...
Blimp1 is an essential regulator of plasma cells. Here we studied its functions in early plasmablast...
To analyze cell lineage specific global transcriptional changes during retinogenesis, we sequenced m...
Sphingosine 1-phosphate (S1P), a pro-tumor survival bioactive lysophospholipid, generated by sphingo...
Dysfunctional Parkin-mediated mitophagic culling of senescent or damaged mitochondria is a major pat...
RNA sequencing (RNAseq) of N/TERT2G keratinocytes transduced with pooled siRNAs targeting YAP1 and T...
HIV reservoirs persist despite successful antiretroviral therapy (ART) and are a major obstacle to t...
To identify regulators of homeostatic eosinophilopoiesis in mice, we took a global approach to ident...
Celecoxib, Rofecoxib Gavage Treated Mice, Aorta RNA-Seq SOURCE: Gregory,Robert,Grant (ggrant@upenn.e...
We molecularly characterized thousands of liver endothelial cells and immune cells using scRNAseq. W...
One critical task in pluripotent reprogramming is to erase the somatic transcriptional program of st...
We examined the transcriptional chagnes modulated by ECBI-11 by perfroming global transcriptome anal...
We profiled total mRNA of pancreas and kidney tissues of 3 different strains (p53-null; In4a/Arf-nul...
Whole genome RNA-sequencing identified Nrf2, MAPK12 and IL-1a as important downstream targets of 1MT...
Mammalian genomes are subjected to epigenetic modifications, including cytosine methylation by DNA m...
There has been an extensive effort underway to profile epigenetic features at the genome-wide scale ...
De novo ASXL1 mutations are found in patients with Bohring-Opitz syndrome, a disease with severe dev...
We inoculated ARPE-19 human retinal pigment epithelial cells with EBOV, and followed course of infec...
We have utilized advanced RNAi technology to dynamically restore endogenous PU.1 expression in p53-d...
We investigated phenotypic differences underpinning obesity susceptibility or resistance based on me...
The macula of the retina has a high ratio of cones to rods and is critical for central vision and vi...
RNA sequencing technology has been carried out in order to compare mRNA expression changes in epithe...
By screening a collection of epigenetic compounds, we find that Lysine-Specific Demethylase 1 (LSD1)...
Calorie restriction (CR) enhances longevity and mitigates aging phenotypes in numerous species. Phys...
To identify genes and pathways sepcific to tumorigenesis, we harvested tissues from two different li...
We have utilized advanced RNAi technology to dynamically restore endogenous PU.1 expression in p53-d...
Non-neuronal cell types such as astrocytes can contribute to Parkinsons disease (PD) pathology. The ...
The growth of neural stem cells is strongly enhanced on myelin in vitro and in vivo. To identify the...
Here, we used next-generation RNA sequencing (RNA-seq) to produce a quantitative, whole genome atlas...
Cellular function is strongly dependent on surrounding cells and environmental factors. Current tech...
Increasing energy expenditure by promoting the thermogenic program in brown adipocytes is a promisin...