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Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Gprc6a|Mck-/- (Gcrp6a skeletal muscle specific knockout)(n=4) are compared to Gprc6afl/fl (WT) mice ...
Our study is the first transcriptome profiling of Chinese NPC patients. These results provide both m...
In order to understand the developmental trajectories of early lymphocyte development it is crucial ...
The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functi...
DNA double-strand breaks (DSBs) and their repair can cause extensive epigenetic changes. As a result...
The quantitative deep bulk MARS-seq analysis demonstrated that DCs from ICAM-1/2 double knockout (DK...
The mouse epidermis develops from a single layer of cells at e9.5 to a fully formed organ at birth c...
Purpose : In this study we observed that inactivation of the genes encoding for the chromatin associ...
We performed additional sequencing of samples from GSM718982, GSM718983 to increase coverage in orde...
The clinical presentation, course and treatment of methamphetamine-associated psychosis (MAP) are si...
Adult mice bearing homozygous floxed Parkin alleles (PMIDs 15249681, 21376232; TM Dawon), with or wi...
Human Cytomegalovirus (hCMV) infects a broad range of the population and establishes life-long laten...
Acute mountain sickness (AMS), which may progress to life-threatening high altitude cerebral edema, ...
T cell antigen receptor (TCR) signaling drives distinct responses depending upon the differentiation...
Rapid pigment regeneration is critical for the continuous function of cone photoreceptors in bright ...
Tumor-associated macrophages (TAMs) have immunosuppressive capacity in mouse models of cancer. Here ...
To study whether acute inhibition of DOT1L induces global chromatin states alterations, we profile a...
In this study, with the help of RNA-sequencing, we show for the first time that long-term absence of...
We report loss of epigentic silencing marks on the inactive X on female mice with lupus like disease...
Here we perform massively parallel single-cell RNA sequencing (scRNA-seq) of human retinas using two...
Conventional 2-D differentiation from pluripotency fails to recapitulate cell interactions occurring...
We examined the brain's choroid plexus and myeloid cell populations isolated from the brain of 5XFAD...
Here, we address whether maternal dietary supplementation at 40 mg/kg chow (FD), restricted to a per...
Purpose: Mller glia are the only glial cell type produced by the neuroepithelial progenitor cells wh...
Using RNA-seq, we report here that primary microglia (PM) cells have a distinct transcriptomic signa...
Purpose: Several members of the tripartite motif (TRIM) family of E3 ubiquitin ligases regulate immu...
Purpose: To investigate the role and mechanism of circRNAs in gastric cancer.; Methods: RNA-seq of r...
Recent studies indicate that cancer-associated fibroblasts (CAFs) are phenotypically and functionall...
Cancer stem cells are responsible for the regenerative properties of tumors, manifested as recurrenc...
We report RNA-seq data from the brown fat and vastus muscles of mice lacking IRF4 in brown fat (BATI...
To explore whether KSHV infection is a risk factor for osteosarcoma development in ethnic Uyghur pop...
To investigate the role of Lsd1 in BAT, we crossed mice harboring conditional Lsd1 alleles (Zhu et a...
The AML1/ETO fusion protein found in acute myeloid leukemias functions as a transcriptional regulato...
Single cell RNA-Seq was performed on ID1 ID3 null endothelial cells to determine the effects of ID g...
Haplo-insufficiency of TCF4 induced by mutations or microdeletion of TCF4 gene causes Pitt-Hopkins D...
The goal of this set is to build expression data using FACS isolated Ret-positiveNaV1.8 cells harves...
Here we show that Zika virus infection induces memory like NK cells that express CD27. This subset s...
The TGF- superfamily member Nodal triggers mesendoderm differentiation in embryonic stem (ES) cells....
In the present study, we established four lenalidomide resistant HMCLs by culturing IMiD responsive ...
Declining immune function with age is associated with reduced lymphoid output of hematopoietic stem ...
Cellular heterogeneity can emerge from the expression of only one parental allele, however it has re...
Our study shows that after extended stimulation of human CD4+CD25+CD127- Tregs in vitro, a stable ce...
During pneumonic plague, the bacterium Yersinia pestis elicits the development of inflammatory lung ...
We report the gene expression profile in BRCA deficient tumors after treatment with saline, nanopart...
Alternative splicing (AS) plays a critical role in cell fate transitions, development and disease. R...
Expression changes of competitive endogenous RNAs (ceRNAs) have been proposed to influence microRNA ...
We performed RNA-seq analyses in BCR-ABL+ cells either expressing or lacking CDK6. 3 replicates per ...
We examined the effect pg IGF1 actibation on cellular contractility and migration in SSC osteoblast ...
Comparative RNA seq analysis of WT and global p73KO Mouse Tracheal Epithelial Cell (MTECs) during t...
The density of the extracellular matrix has a dramatic impact on the gene expression profile of T ce...
We evaluated by RNA-seq obveral transcripts in B cells (resting and activated for 2 days with LPS) s...
We analyze the contribution of alternative splicing to the transcriptional complexity in adipose tis...
Primary human foreskin fibroblasts (HFF) were infected with wild-type herpes simplex virus 1 (HSV-1)...
Integrator (INT) is an RNA polymerase II (RNAPII)-associated complex that was recently identified to...
The goal of this study was to determine the transcriptional changes associated with breast cancer ce...
We developed a tunable ligation technology to alter beads used for to capture mRNA for single-cell R...
Genetically encoded unnatural amino acids provide powerful strategies for modulating the molecular ...
The debilitating autoimmune disease Systemic Lupus Erythematosus (SLE) is closely associated with To...
We analysed the effect on the genomic localisation of cohesin (Stag1 and Scc1) and CTCF in CTCF, Smc...
Using RNA-seq, we report here that anthrax lethal toxin (LeTx) induces immunosuppression in human lu...
Since the first generation of induced Pluripotent Stem cells (iPSCs), several reprogramming systems ...
We sequenced two types of interneurons from adult mouse frontal cortex across multiple library batch...
Goal of this study was to examine gene expression changes upon conditional deletion of beta-catenin ...
Gene expression differences during development provide the basis for adult phenotypic differences. T...
It is unknown how nave CD8 T cells that harbour different and distinct T cell receptors to the same ...
We studied the role of the histone methyltransferase DOT1L in T cell development and differentiation...
We did bulk and single cell RNA sequencing of blastocysts, blastoids, trophoblast stem cells (TSC) a...
Goal: Study resistance mechanisms to ATP-competitive vs. allosteric AKT inhibitors, in prostate canc...
Tissue-resident memory T cells (Trm) are non-circulating memory T cells that localize to portals of ...
Our study looks at the liver circadian transcriptome. SOURCE: Andrés HidalgoImaging of the Cardiovas...
The brain renin-angiotensin system (RAS) stimulates resting metabolic rate in part through a mechani...
Generally, when LCM is used in diverse transcriptomic analyses, several hundred, if not thousands, o...
Targeted disruption of the embryonic stem cell (ESC) self-renewal and pluripotency factor NANOG dimi...
To examine Ikaros tumor suppressor mechanisms, we have utilized inducible RNAi to dynamically restor...
We performed ChIP-seq on mouse lens epithelial cells (TN4) and mouse newborn lens. Genome-wide bindi...
We generated RNASeq data to investigate the expression levels of RNases in differentiated and undiff...
A growing body of literature has proposed cell-autonomous tumor suppressor functions for the mir-143...
Innate immune memory, also refered to as trained immunity (TRIM) is the phenomenon whereby innate im...
Embryonic gene expression intricately reflects anatomical context, developmental stage, and cell typ...
We analyze the contribution of alternative splicing to the transcriptional complexity in adipose tis...
To determine potential targets of KLF5 we performed RNA-sequencing on jejunal crypts isolated from K...
The RNA-seq results reveal Tetra-Pt(bpy) has no effect on gene expression. SOURCE: Yong Zhao (zhaoy8...
Analysis of the cystic fibrosis gene Cftr in the colon and small intestine of Cftr-deficient murine ...
we find METTL3 associates with polyribosomes and promotes translation. METTL3 depletion inhibits tra...
Purpose: To characterize transcriptional changes associated with inhibition of Dot1l in 2 inv(16) pa...
The Ras-family small GTPase RAB25 is involved in numerous aspects of endosomal protein trafficking a...
Direct lineage reprogramming involves the remarkable conversion of cellular identity. Single-cell te...
We report downstream gene expression changes in stem cells of the adult mouse hair follicle upon con...
Bone marrowderived mesenchymal stem/progenitor cell mRNA profiles of WT and Tet2/ mice were generat...
Here we report the transcriptome data of 236 single cells freshly isolated from mouse embryos on day...
RNA-seq libraries purified from the visual cortices of neurons expressing Emx-, GAD2-, PV-, SST-, or...
Analysis of hepatic stellate cells (HSCs) isoltaed from ASMA-HAS2 transgenic and HSC-specific Has2 k...
Despite recent improvements many cancer patients do not respond to immune or targeted drugs and requ...
Toxoplasma gondii is an obligate intracellular Apicomplexan parasite capable of invading and survivi...
We performed whole transcriptome sequencing of human monocytes that were co-cultured with estrogen r...
We aim to investigate the role of SHARPIN in breast cancer progression. MCF-7 cells were used as the...
Arid1a is the subunit of SWI/SNF complex, which was reported to guide SWI/SNF to DNA. Here, we found...
Coordinated repression of gene expression by evolutionarily conserved microRNA (miRNA) clusters and ...
Purpose: In Huntington disease (HD) subtle symptoms in patients may occur years or even decades prio...
Translating ribosome affinity purification technology was used to isolate mRNAs from cerebellar Purk...