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Sequencing-based assays page 40
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GSE77250: Total RNA sequencing of APC mutant and wt colonic organoids
We report elevated expression levels of genes involved in colon cancer in samples that carry mutatio...
GSE53983 (mouse): Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation
Purpose:The purpose of this study is to create unbiased, stage-specific transcriptomes by RNA-seq an...
GSE79249: Identification of long noncoding RNAs regulated by p53
Analyize the transcriptpme regulated by p53 in 3 pairs of isogenic p53WT and p53KO colorectal cancer...
GSE84329: RNA sequencing of Cyfip2N/- and Cyfip2N/N mice
RNA-seq analysis of 8 Cyfip2N/- and 8 Cyfip2N/N mice. Cyfip2N/- are mice contain one copy of the B6N...
GSE79018: Functional characterization of DNA methylation in the oligodendrocyte lineage [RNASeq_Dnmt1cKO_OPC]
Oligodendrocytes derive from progenitors (OPC) through the interplay of epigenetic and transcription...
GSE78996: Characterisation of Transcriptional Changes in the Spinal Cord of the Progressive Experimental Autoimmune Encephalomyelitis ABH Mouse Model by RNA Sequencing
RNA sequencing was used to explore global gene expression in the chronic relapsing and secondary pro...
GSE83549: RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide
To determine how targeting the disruption of PRC2:SMN-AS1 interactions might affect PRC2 targets glo...
GSE77288: Batch effects and the effective design of single-cell gene expression studies
Single cell RNA sequencing (scRNA-seq) can be used to characterize variation in gene expression leve...
GSE109439: Transcriptomes of human monocytes and monocyte-derived macrophages with or without glucocorticoid treatment
Glucocorticoids (GCs) are essential steroid hormones that regulate the immune system. GCs have been ...
GSE134704: Cortical transcriptome reveals widespread inflammation in brain of Gaa-/- mice
Glycogen storage disease type II (Pompe's disease) is a lysosomal storage disorder which is associat...
GSE71387: EZH2 inhibition as a targeted therapy for H3K27M mutant pediatric gliomas [RNA-Seq]
Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive brain tumour that is located in the p...
GSE75868: Naive Pluripotent Stem Cells Display Transcriptional and Epigenetic Signatures of the Human Pre-Implantation Embryo
Significant interest has been devoted to the isolation of human pluripotent stem cells displaying th...
GSE75513: Rage null mice exposed to cigarette smoke demonstrate attenuated inflammatory, oxidative and ER stress responses in alveolar macrophages
Analysis of alveolar macrophage gene expression in C57BL6 wild-type and RAGE null mice exposed to ci...
GSE90094: The Ets-family transcription factors PU.1 and SpiB are redundantly required by mature B cells to sense and respond to environmental cues
Humoral immunity requires B cells to respond to multiple stimuli, including antigen, membrane and so...
GSE77879: Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors
Although clonal studies of lineage potential have been extensively applied to organ specific stem an...
GSE73216: Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis [RNA-Seq]
Cohesin complex members have recently been identified as putative tumor suppressors in hematologic a...
GSE79028: Transcriptomic analysis of wild type and Del(Hotair)-/- mouse tissues
Despite decades of interest, the mechanisms that control Hox gene expression are not yet fully under...
GSE76010: The Histone Variant MacroH2A1.2 is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1
Histone variants complement and integrate histone post-translational modifications in regulating tra...
GSE81259: Transcriptional profiling reveals monocyte signature associated with JIA patient poor response to methotrexate
The mechanisms that determine the efficacy or inefficacy of methotrexate in juvenile idiopathic arth...
GSE126537: Rorc disruption in human FG pancreatic cancer cells
Rorc disruption in human FG pancreatic cancer cells SOURCE: Michael Hamilton (mihamilton@ucsd.edu) -...
GSE95734: A somatic mutation in erythro-myeloid progenitors causes (late-onset) neurodegenerative disease
The pathophysiology of neurodegenerative diseases is poorly understood, and therapeutic options are ...
GSE76132: Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses
One of the most common genetic alterations in acute myeloid leukemia is the internal tandem duplicat...
GSE97478: Single cell RNA sequencing of interneurons of the mouse dorsolateral striatum I
In this study we performed single-cell sequencing of striatal interneurons, revealing st...
GSE97249: Cell intrinsic changes in transcription of nave CD4 T cells upon S1pr1 deletion
Nave CD4 cells (CD45.2+CD4+,CD62L high,CD44 low) isolated from lymph nodes of mixed bone marrow chim...
GSE94597: Down-regulation of E protein activity augments an ILC2 differentiation program in the thymus
Innate lymphoid cells (ILCs) are important regulators in various immune responses. Current paradigm...
GSE97527: PAF1 regulation of promoter-proximal pause release via enhancer activation
Gene expression in metazoans is regulated by RNA Polymerase II (Pol II) promoter-proximal pausing an...
GSE76909: Widely Interspaced Zinc Finger Motifs, Wiz, binds promoters containing CTCF-binding sites and is required for normal neural function in the mouse
Mice heterozygous for a null mutation in Widely-interspaced zinc finger, Wiz, were produced in a scr...
GSE71876 (mouse): Survival of pancreatic cancer cells lacking KRAS function
Activating mutations in the proto-oncogene KRAS are a hallmark of pancreatic ductal adenocarcinoma (...
GSE135050: RNA sequencing analysis of hepatic transcriptome profiles in experimental nonalcoholic steatohepatitis
Two-month-old C57BL/6J male mice were placed on either chow diet or a diet enriched in high fat, cho...
GSE74155: Single-cell analysis of allelic gene expression in pluripotency, differentiation and X-chromosome inactivation
We sequenced the mRNAs of embryonic stem cells (ESCs) cultured in different conditions. The two lin...
GSE81550: RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues
Three pairs of hepatocellular carcinoma and adjacent non-tumor tissues were from 3 male patients suf...
GSE142871: PIM kinase inhibition in HCC xenograft
Human HCC cell line, MHCC-97L, was subcutaneously injected to BALB/c nude mice. Two weeks post injec...
GSE76929: RNA sequencing of C57BL/6J mice, heterozygous for knockout of Hnrnph1 gene, as well as C57BL/6J mice controls
Previous studies of congenic lines of C57BL/6J-DBA/2J mice compared to C57BL/6 mice revealed a 0.23 ...
GSE76130: Alternative routes to induced pluripotent stem cells revealed by reprogramming of neural lineage
During the reprogramming of mouse embryonic fibroblasts (MEFs) to induced pluripotent stem cells, th...
GSE77929: Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome
Most Lyme disease patients treated with appropriate antibiotics recover rapidly and completely, but ...
GSE76922: Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2
Purpose: 22q11 Deletion Syndrome (22q11DS) is a disorder caused by a heterozygous deletion of 3 mill...
GSE87404: Epigenetic stress responses induce muscle stem cell aging by Hoxa9 developmental signals [RNA-seq]
Background and Aims: Analysis of aging-induced impairments in satellite cells (SCs) the stem cells ...
GSE142987: RNA-seq analysis of liver cancer patients' plasma
Liver cancer is one of the most lethal cancers worldwide. Liquid biopsy provides a noninvasive appro...
GSE89992: Non-Cell-Autonomous Tumor Suppressor Activity of the Homeobox Gene Cdx2 in the Gut
This dataset describe the transcriptomic profiling of cecum, stomach and ileum from wild type, cdx2 ...
GSE76932: Next generation sequencing comparing effects of vehicle, PTH, and YKL-05-093 in Ocy454 cells
Purpose: The goals of this study are to compare the effects of vehicle, PTH, and YKL-05-093 on gene ...
GSE75951: Transcriptome of mouse preimplantation development [Xist KO]
Purpose: The goals of this study are to establish a dynamic roadmap of imprinted X chromosome inacti...
GSE78146: Methylation and gene expression profiling in Dnmt3a-deficient chronic lymphocytic leukemia and peripheral T-cell lymphoma in mice.
The goal of this study was to identify genome-wide methylation changes and aberrant gene expression ...
GSE97367 (mouse): BioProject PRJNA381064: Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage
In order to study the green anole dosage compensation mechanism we generated strand-specific RNA-seq...
GSE141072: Sex differences in LCWE-induced model of Kawasaki Disease vascultitis and response to Anakinra treatment
Analysis of abdominal aorta gene expression in the LCWE-induced Kawasaki Disease vasculitis model an...
GSE139529: Comparison of whole blood transcriptional changes induced by menignoccocal capsular group B vaccines in mice
Whole blood RNA-seq was leveraged to explore gene expression changes induced in mice 24 hours after ...
GSE76359: Deciphering the importance of the palindromic architecture of the immunoglobulin heavy chain 3 regulatory region.
The IgH 3 regulatory region (3RR) controls class switch recombination (CSR) and somatic hypermutatio...
GSE97945: ChAHP (Adnp, Chd4, HP1) mediates sequence-specific recruitment of HP1 independent of H3K9 methylation
Activity-dependent neuroprotective protein (ADNP) is one of the most frequent autism spectrum disord...
GSE99164: Next Generation Sequencing Quantitative Analysis of Tshz1GFP/+ and Tshz1GFP/RA purified amygdalar ITCs
RNA sequencing was performed on the transcriptomes of amygdalar ITCs from Tshz1 GFP/+ embryonic mice...
GSE135330: Microglial microRNAs mediate sex-specific responses to tau pathology
Sex is a key modifier of neurological disease outcomes. Microglia are implicated in neurological dis...
GSE73221: Progressive chromatin condensation and H3K9 methylation regulate the differentiation of embryonic and hematopoietic stem cells
Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, bu...
GSE122644: Apical progenitors remain multipotent throughout cortical neurogenesis
We used FlashTag, a method to pulse-label and isolate APs in the mouse neocortex with high temporal ...
GSE72105: A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation
To study the function of E3 ligase Huwe1 knockdown on C2C12 proliferation and differentiation, we us...
GSE95435: Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease [1]
Intestinal health is sustained by cooperation between diverse cell types, including epithelial cells...
GSE78209: Pervasive TTP binding but selective target mRNA destabilization in the macrophage transcriptome [RNA-Seq_2]
Precise control of mRNA decay is fundamental for robust yet not exaggerated inflammatory responses t...
GSE90816: Hox Abdominal-B Genes in the Developing Kidney
The Hox complex consists of 39 genes arranged in 4 clusters of flanking genes and 13 paralogous grou...
GSE147976: RNA-seq analysis in NRG1 and enzalutamide treated 22Pc-EP cell line
Transcriptome prolifing analysis was performed in 22Pc-EP cells to identify differentially regulated...
GSE78199: BASP1 modifies the Tamoxifen response
We report that WT1 transcriptional repressor protein BASP1 interacts with oestrogen receptor alpha (...
GSE134031: TREM2regulatesmicroglial lipid metabolismduring aging in mice [RNA-Seq]
TREM2 is a microglial-specific gene implicated in late-onset Alzheimer's Disease (AD). Recent studie...
GSE76983: Single-cell RNA-seq of sorted and micro-dissected mouse bone marrow cells
We here systematically studied the interaction network of bone marrow cells. To this end, we micro-d...
GSE112415: A network of noncoding regulatory RNAs acts in the mammalian brain I
Noncoding RNAs (ncRNAs) play increasingly appreciated gene-regulatory roles. Here, we describe a reg...
GSE90824: Blimp1 induces transient metastatic heterogeneity in pancreatic cancer [RNA-seq]
Purpose: Due to its high metastatic proclivity, pancreatic ductal adenocarcinoma (PDAC) is one of th...
GSE81266: Ileal pouch transcriptomics reveal shared pathogenesis between pouchitis and ulcerative colitis
UC pouchitis is a potential model of UC. We prospectively examined the pouch transcriptomes of UC an...
GSE79613: iPSCs Reveal Protective Modifiers of the BMPR2 mutation in Pulmonary Arterial Hypertension
The goal of this study is to compare transcriptome profiling (RNA-seq) in controls, unaffected BMPR2...
GSE72095: Temporal transcriptomics suggest that twin-peaking genes reset the clock
The mammalian suprachiasmatic nucleus (SCN) drives daily rhythmic behavior and physiology, yet a det...
GSE76978: A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia
Transcriptome analysis by RNAseq of leukemia model promoted by MLL-Af4 or MLL-AF9 fusion proteins. W...
GSE79087: REV-ERB influences stability and nuclear localization of the glucocorticoid receptor
We report here that REV-ERB influences nuclear localization of the glucocorticoid receptor and vice ...
GSE104423: Heart failure patients' peripheral blood mononuclear cell gene expression profiles before mechanical circulatory support
This data represents whole transcriptome total RNA gene expression profiles of peripheral blood mono...
GSE77523: Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq]
Direct conversion of somatic cells into neurons holds great promise for regenerative medicine. Howev...
GSE103799: PMP22 antisense oligonucleotides reverse clinical, pathological, and molecular features of Charcot-Marie-Tooth disease type 1A
RNA sequencing data from sciatic nerves of C22 and wildtype littermates SOURCE: Sagar,S,Damle (sdaml...
GSE85118: INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer [RNA-seq]
Epigenetic regulators are attractive targets for the development of new cancer therapies. Among them...
GSE77541: Genome-wide expression profile in Fh1-competent vs Fh1-deficient mouse kidney cells
Comparison of the transcriptome of immortalised mouse kidney epithelial cells either wt for Fh1 or F...
GSE77646: Gene expression profiling of AR deletion in prostate luminal cells
Benign prostatic hyperplasia (BPH) is a common urological disease that adversely affects quality of ...
GSE76389: FOXE3 Contributes to Peters Anomaly through Transcriptional Regulation of an Autophagy Associated Protein termed DNAJB1
FOXE3 is a lens specific transcription factor that has been associated with anterior segment ocular ...
GSE76371: mRNA expression profile of Lymphocytes
V24 invariant natural killer T (iNKT) cells are a subset of T lymphocytes implicated in the regulati...
GSE76425: CDK4/6 inhibition sensitizes myeloma to lenalidomide by reducing the MEIS2 to CRBN ratio that accelerates IKZF1 and IKZF3 degradation
The RNA-seq data presented in this study include libraries from bone marrow plasma cells (BMPC), pri...
GSE77682: RNA-seq of human fibroblasts after irradiation
Comparing gene expression level by Illumina sequencing of fibroblasts after irradiation SOURCE: JenA...
GSE135527: Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion
We report the global gene expression effects in TSC-deficient and TSC wild type cells after treatemn...
GSE77597: RNA-Sequencing of HUVEC treated with Tie2 activating antibody
We analyzed genome-wide transcriptional changes induced by ABTAA+Ang2, using RNA-seq analysis of HUV...
GSE128588: Global gene expression of SLC35F2 Knock-out (KO) H9 with control hESCs
Analysis of SLC35F2 KO hESCs compared with control hESCs. In order to investigate whether SLC35F2 KO...
GSE83555: WT and AUF1 KO satellite cell RNA-sequencing
Following skeletal muscle injury, muscle stem cells (satellite cells) are activated, proliferate, an...
GSE104644: Reduced Type I Interferon response signature detected in dendritic cells from prediabetic NOD mice compared to C57BL/6.g7 and Rag KO
Investigating type I interferon in prediabetic stage of DCs from NOD mice compared to C57BL/6.g7 and...
GSE77784 (mouse): MOF acetyl transferase regulates transcription and respiration in mitochondria
Histone acetylation is sensitive to metabolic cues, however interplay between histone acetyl transfe...
GSE77720: C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD
Noncoding expansions of a hexanucleotide repeat (GGGGCC) in the C9orf72 gene are the most common cau...
GSE77005: The Schizophrenia Risk Gene Product Satb2 Regulates miRNAs Expression and Long-Term Memory in Adult CNS
(i) The hippocampal transcriptome was analyzed in mice that lack the SatB2 gene; (ii) Satb2 binds ...
GSE77422: The effect of Abl kinases on non-small cell carcinoma global transcriptome
To gain insight into the signaling pathway(s) required for ABL1/ABL2-dependent non-small cell carcin...
GSE81301: Proteogenomic Reveals Biomarkers and Therapeutic Targets in Lymphoid Cancer
Here we find the transcriptional network regulated by ALK oncogenic activitiy in two Anaplastic Larg...
GSE141562: Chronic rare DUX4 expression in mouse drives transcriptional similarities to human FSHD in whole muscle and fibroadiopgenic progenitors
RNA-seq data was obtained on various samples from the iDUX4pA mouse model for FSHD and from control ...
GSE72607: Intergenerational consequences of gene-environment induced epigenetic dynamics at rDNA in the mouse (RNA-Seq)
The ability of environmental exposures in one generation to elicit phenotypic outcomes in subsequent...
GSE141585: Next Generation Sequencing Facilitates Quantitative Analysis of IFN- induced-MMP2/9 inhibition compared to vehicle control cells' Transcriptomes
Expression profiles of SB-3CT treated A375 human melanoma cell lines and vehicle control group with ...
GSE72069: TGF- Tumor Suppression Through A Lethal EMT
TGF- is a major tumor suppressor in gastrointestinal (GI) and squamous carcinomas, which exhibit fre...
GSE76987: Gene signature in sessile serrated polyps identifies colon cancer subtype
RNA sequencing analysis of gene expression in serrated colon polyps, uninvolved colon and control co...
GSE141387: O-glycan initiation directs distinct biological pathways and controls epithelial differentiation
We used RNA_Seq to quantify cellular transcripts in human spontaneously immortalized HaCaT keratinoc...
GSE83559: Transcriptome changes due to nuclear penetration of cancer extracellular vesicles
Extracellular membrane vesicles (EVs) function as vehicles of intercellular communication in autocri...
GSE92257: RNA fate determination through co-transcriptional methylation of newely synthesized transcripts
Using murine embryonic stem (mES) cells, here we show that two RNAi factors, Dgcr8 and the RNAseIII ...
GSE104817: RIG-I-Like-Receptors Induce Unique and Complimentary Transcriptional Programs Following West Nile Virus Infection Leading to Macrophage Polarization and Protection
The study shows that RLRs drive distinct immune gene activation and polarization of the immune respo...
GSE77408: Fbxo32 mediated gene expression program underlies EMT and metastasis
The epithelial-mesenchymal transition (EMT) is a process by which cells lose their cell contacts and...
GSE83550: Ribo-zero RNAseq Mouse distal colon DSS Colitis model of genetically engineered mice
Ribo-zero RNAseq experiments were carried out with mouse distal colon DSS Colitis model of genetical...
GSE92317: Transcriptome assay of maternal mRNA degradation in ERK-deleted oocytes
We analyzed the functions of ERK in maternal mRNA degradation in mouse oocytes. By comparing the deg...
GSE104828: TET2 regulates osteoclast differentiation by interacting with RUNX1 and maintaining genomic 5-hydroxymethylcytosine
In this study we show that Tet2 helps regulate the differentiation of macrophages to osteoclases SOU...
GSE72343: Circuit-wide transcriptional profiling reveals region specific gene co-expression networks regulating depression susceptibility
Depression is a complex and heterogeneous disorder and a leading contributor to the global burden of...