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Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Characterization of different astrocytes soruces was done using RNAseq including samples from human ...
Here, we describe an approach to enrich newly transcribed RNAs from primary mouse neurons using 4-th...
Chromatin regulators control cellular differentiation by orchestrating dynamic developmental gene ex...
In this study, we demonstrate that the UBN1 or UBN2 subunit is mainly responsible for specific recog...
p53 is a transcriptional activator that induces myriad target genes. However, those p53-inducible ge...
Circular RNAs (circRNA) are special non-coding RNAs. They are widely present, but with unknown funct...
RNA-seq technology was used to reveal the transcriptome changes of tubular epithelia in response to ...
Aberrant expression of immune checkpoint protein programmed death ligand-1 (PD-L1) promotes immune t...
The goals of this study were to advance the understanding of the distinct impact of amphetamine acro...
Mesenchymal stromal cells (MSC) are involved in the pathogenesis of myelodysplastic syndromes (MDS) ...
Although many long non-coding RNAs (lncRNAs) are controlled by genomic imprinting, their roles often...
To explore potential molecular mechanisms underlying the temporal process of DNA damage and repair i...
Inflammatory bowel disease (IBD) is a challenging condition with limited therapeutic options. Inflam...
Using our computational method SynGeNet to evaluate genomic and transcriptomic data characterizing f...
The NOTCH1-driven MYC enhancer (NMe) is essential for T cell development, transformation and the dev...
T cell receptor (TCR) stimulation of nave CD8+ T cells initiates reprogramming of cis-regulatory lan...
MLL/SET methyltransferases catalyze methylation of histone 3 lysine 4 and play critical roles in dev...
Wild type or HIPK2-/- immortalized bone marrow-derived macrophages (iBMDM) were infected with VSV fo...
By their impact on nuclear organisation, enhancers are master regulators of cell fate. We thus devel...
Mouse Embryonic Stem (ES) cells have been cultured under chemically defined conditions in the absenc...
The cell cycle is known to regulate cell proliferation and cell fate decisions, the underlying mecha...
The widespread adoption of transcriptional profiling has led to immense repositories of data that ma...
Here we describe broad anti-proliferative activity of potent, selective, reversible inhibitors of pr...
Liver sex-specific long noncoding RNAs (lncRNAs) were identified based on three pools of male and th...
We have used RNA-seq to examine RNA differential expression among three populations, normal basal ce...
We have shown that Notch signalling pathway is a potent regulator of thymic epithelial progenitor ce...
The mechanisms underlying degeneration of the specific neurons in the striatum of Huntingon's Diseas...
Acute aerobic exercise has been shown to improve skeletal muscle mitochondrial function and complete...
Proximal tubule has a remarkable capacity for repair after acute kidney injury. Whether dedifferenti...
We report RNAseq data from subsequent passages of five organoid cultures. SOURCE: Georgios Vlachogia...
We reoprt that transcriptional level of distal VH is dependent of both intronic enhancer (E) and in...
We demonstrate that progression along EMT occurs along a continuum and that interruption of key sign...
Ten-eleven translocation (Tet) family-mediated DNA oxidation represents a novel epigenetic modificat...
Interleukin 33 (IL33) is an inflammatory cytokine released during necrotic cell death. The epitheliu...
Purpose: Microglia are essential for central nervous system (CNS) homeostasis and innate neuroimmune...
Depletion of immunosuppressive tumor-associated macrophages (TAM) or reprogramming towards a pro-inf...
Here we generated transcriptomes of dissected cortical tissue of Dmrt3 and Dmrt5 single knockout, of...
How genomic information is selectively utilized to direct spatial and temporal gene expression patte...
We identified KDM3A, a demethylase of histone H3K9me1/2, as a positive regulator for hippo target ge...
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes...
Systemic sclerosis (SSc) is a devastating disease affecting the skin and internal organs. Dermal fib...
Analysis of mouse glioma tumors (in RAG1-/- mouse host) overexpressing Control(C) or Slug(S) viruses...
We performed scRNA seq according to the CEL-seq2 protocol in order to define the equivalent developm...
Purpose: The goal of this study was to characterize molecular stress responses on transcriptional le...
Genome-wide transcriptional survey in peripheral blood mononuclear cells (PBMCs) by RNA-Seq in schoo...
Bptf, a component of NURF chromatin-remodeling complex, is essential for maintaining the pool size a...
We used single-cell RNA-seq to reconstruct differentiation paths of cardiac progenitors in two seque...
MLL-fusions represent a large group of leukemia drivers, whose diversity originates from the vast mo...
Alterations to corticostriatal glutamatergic function are early pathophysiological changes associate...
Mouse embryonic stem (ES) cells cultured in defined medium with MEK and GSK3 inhibitors (2i) resembl...
The serrated adenocarcinoma subtype accounts for 15-30% of all colorectal cancers (CRCs) and is aggr...
AXL is activated by its ligand GAS6 and is expressed in triple-negative breast cancer cells. We repo...
We reported for the first time that DMKG plus B87 kills cancer cells through a MDM2-dependent cell d...
Excessive mRNA translation downstream of group I metabotropic glutamate receptors (mGlu1/5) is a cor...
In order to explore possible consequence of ASCT1 (Slc1a4) deletion in neurodevelopment, we carried ...
We used high throughput sequencing to analyze the gene expression profiling of human uterine smooth ...
We have developed a robust methodology for the derivation of kidney organoids from human pluripotent...
Profound distinctions exist between fetal liver (FL) and adult bone marrow (BM) hematopoietic stem c...
Alternative polyadenylation (APA) produces mRNA isoforms with different 3UTR lengths. Previous studi...
While gene expression dynamics have been extensively catalogued during hematopoietic differentiation...
RNA-seq of wild type embryonic stem cells and cells bearing a mutation that perturbs the OGT-TET1 in...
Purpose: Trichloroethylene (TCE) and tetrachloroethylene (PCE) are ubiquitous environmental contamin...
We report transcriptome profiling of bone marrow niche subsets at the population level. Additionally...
Single-cell transcriptome sequencing of E14.5 mouse hearts from Adamts19 wild-type and Adamts19 knoc...
An improved mechanistic understanding of the thyroid hormone (TH) action on bile acid (BA) synthetic...
We report that IKZF2 is required for maintaining chromatin accessibility in leukemic stem cells in m...
This experiment was conducted to identify mRNA transcripts alteration in liver of Ern1 liver specifi...
Gestational and perinatal disruption of neural development increases the risk of developing schizoph...
There is considerable crosstalk between satellite cells, endothelilal cells and muscle fibers. Trans...
The NUP214-ABL1 fusion is a constitutively activated tyrosine kinase that is significantly associate...
Objectives: Treatment with the second and third generation BCR-ABL1 tyrosine kinase inhibitors (TKIs...
Purpose: We hypothesised that neuregulin 1 type III would reverse CHN. Using a faithful mouse model ...
We have performed quantitative H3K9ac ChIP-seq and RNA-seq from untreated and 3h, 6h insulin treated...
Our data analysis unveils that differentially expressed long noncoding RNAs and some wrongly transcr...
This study is the first characterization of the first trimester placenta transcriptome, highlighting...
RNA sequencing data of TPC-1 cells (TC cell line) after co-culture with TC-induced macrophages. We ...
We compared transcripts from somatostatinpositive inteneruons in the migrating marginal zone and sub...
Genetic linkage analysis suggested that GKAP, a scaffold protein of the NMDA receptor (NMDAR), was a...
Stable changes in chromatin states and gene expression in cells of the immune system form the basis ...
Cells belonging to trophoblast lineage are required for proper implantation and placentation, as wel...
Adult muscle stem cells (MuSC) are quiescent with a localization between myofibers and basal lamina....
The type 2 cytokines interleukin (IL)-4, IL-5, IL-9 and IL-13 play critical roles in stimulating inn...
Although c-Myc is essential for melanocyte development, its role in cutaneous melanoma, the most agg...
RNA-seq libraries purified from rLCMV-Cre infected neurons using the Ribotag allele. Seq libraries a...
Dieldrin is a pesticide with a suspected impact on chromatin. Here, we have exposed Jurkat cells to ...
Epigenetic effects of environmental chemicals are under intense investigation to fill existing knowl...
[Purpose] To define the traditional profile of EcTMs, RNA seq analysis were parformed on EcTMs and n...
We performed RNA-seq experiments, one with the WT control and Mir182M/M osteoclast precursors at bas...
Measuring the effects of the compound JIB-04 on global transcription, NFkB pathway-related genes, an...
RNAseq was performed on WHIM2 and WHIM30 PDX mammary tumors, brain metastases, and single cell suspe...
RNA sequencing (RNAseq) of unstimulated cells transiently expressing PKI1-24 or inPKI1-24 as a contr...
Raw files corresponding to diverse immunocyte populations sequenced using ImmGen's standard ultra-lo...
The goal of this study is to reveal the globle changes of oocyte transcriptome after mutations of Ma...
Focused ultrasound (FUS) mediated blood brain barrier disruption (BBBD) is a promising strategy for ...
We present single-cell mRNA-Sequencing of various endothelial and hematopoietic populations isolated...
Villar and intervillar epithelial cells were FACs isolated from P0, P3, P6, or P10 CD1 mouse medial ...
The goal of this study was to determine the transcriptional difference between WT and PIN1 knockout ...
The MEF2B transcription factor is recurrently mutated in germinal-center (GC)-derived B-cell lymphom...
Induced pluripotent stem cells (iPSC) were generated from two patients affected by ankyloblepharon e...
Temporal control of physiology requires the interplay between gene networks involved in daily timeke...