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Pluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
YAP/TAZ, downstream effectors of the Hippo pathway, are important regulators of proliferation. Here ...
Undifferentiated and differentiated Keratinocytes (AG1478 treated) were stained with antibody-RNA co...
Balanced symmetric and asymmetric divisions of neural progenitor cells (NPCs) are crucial for orderl...
The intestinal epithelium is a highly structured tissue composed of repeating crypt-villus units. En...
To fully comprehend how genetic variants influence phenotypes, we must understand the functions of t...
Faithful transcription initiation is critical for accurate gene expression, yet the mechanisms under...
Our study shows that acute myeloid leukemia (AML) cells require the BRD9 subunit of the SWI/SNF chro...
We have developed a novel immunocompetent multi-lesion mouse model of activated B cell diffuse large...
TET enzymes are dioxygenases that promote DNA demethylation by oxidizing the methyl group of 5-methy...
Lack of Mirc11 significantly reduces NK cell-mediated cytokine production in vivo; Mirc11 cluster ta...
The transcription factor Helios is expressed in a large subset of Foxp3+ Tregs of both mouse and man...
LARP1 has been proposed to control the translation of TOP mRNAs downstrteam of mTORC1. Here we used ...
We established a de novo approach of generating T cells from mouse ESC/iPSC by defined transcription...
We performed differential mRNA analysis in WT and BRG1 KO cells during cardiac precursor and cardio...
The objective of this experiment was to compare the affect of H3B-5942 treatment on global gene exp...
Chimeric antigen receptor T (CAR T) cells targeting CD19 have achieved breakthroughs in the treatmen...
Upon virus infection,pluripotent stem cells neither induce nor respond to canonical Type I interfero...
The RNA binding protein Dazl is essential for gametogenesis, but its direct in vivo functions, RNA t...
T-cell acute lymphoblastic leukemia (T-ALL) is a malignancy of T cell progenitors that in most patie...
Database of gene expression in different haematopoietic cell types at haemosphere.org. SOURCE: Carol...
We studied a murine AVF in mice with chronic kidney disease (CKD). SOURCE: Daniel,Rothschild,OBrien ...
Lack of Mirc11 significantly reduces NK cell-mediated cytokine production in vivo; Mirc11 cluster ta...
Peripherally derived macrophages infiltrate the brain after bone marrow transplantation and during c...
SET domain containing 2 (Setd2), encoding a histone methyltransferase, is associated with many hemat...
Crosstalk between mesenchymal stromal cells (MSCs) and hematopoietic stem and cells (HSCs) is essent...
The goal of the study is to perform unbiased transcriptome analysis on spinal cord samples of immuni...
Many patients with advanced cancers achieve dramatic responses to a panoply of therapeutics, yet ret...
Heart muscle cells, cardiomyocytes, are highly differentiated cells that usually do not proliferate ...
Epitranscriptomic regulation controls information flow through the central dogma and provides new op...
RNA-seq of WT, Tet2-het and Tet2-KO mTSCs in stem-state, RNA-seq of WT and Tet2-KO mTSCs in vitro di...
Pancreas development involves a coordinated process in which an early phase of cell segregation and ...
We developed Microwell-seq, a high-throughput and low-cost scRNA-seq platform using simple, inexpens...
The 9p21.3 cardiovascular disease locus is the most influential common genetic risk factor for coron...
The function of bone marrow sinusoidal endothelial cells may change upon the ablation of classical d...
Using a mouse model overexpressing human SNCA and profiling the striatal transcriptome, we assessed ...
Total RNA of mice tissues (liver, small intestine, lung and kidney) was extracted using liquid N2 an...
Podocyte injury is the hallmark of proteinuric kidney diseases, such as Focal Segmental Glomeruloscl...
Microenvironment is known to influence cancer drug response and sustain resistance to therapies targ...
Melanoma is an aggressive neoplasm with increasing incidence that is classified by the NCI as a reca...
Control untransduced or anti-HER2 CAR (Ad5f35 transduced) human macrophages were exposed to control ...
While variations in gene transcription networks in models of atherosclerosis have been reported, the...
Purpose: The goal of this study is to compare the NGS-derived from ventricular trascriptome profilin...
The long noncoding RNA, Xist, is critical for initiation and establishment of X- chromosome inactiva...
Intestinal organoids are complex three-dimensional structures that mimic cell type composition and t...
We performed a transcriptome comparison of double-negative developing thymocytes from the DN3-4 popu...
Spermatogonial stem cells (SSCs) have the dual capacity to self-renew and differentiate into progeni...
Purpose: To ensure that ABX464 acted specifically on HIV splicing and did not significantly or globa...
Our data demonstrate that CARM1 is required for transcriptional activation of a subset of retinoic a...
Glucagon, an essential regulator of glucose and lipid metabolism, also promotes weight loss, in part...
Many liver pathologies ranging from cancer to genetic metabolic diseases are amenable to cellular re...
The objective of this experiment was to determine the affect of H3B-5942 treatment on global gene e...
The goals of this study are to compare transcriptome profiling (RNA-seq) of bone marrow derived macr...
We explore culture coniditions that promote the expansion of engraftment-compentent olfactory basal ...
We have performed modular analyses to decipher the global transcriptional response and capture a bre...
We report the application of high-throughput profiling of gene expression in human dental pulp cells...
Empirical and anecdotal evidence have associated stress with accelerated hair greying (formation of ...
To investigate the disease-associated differences in gene expression pattern during neuro developmen...
The cure rate for late stage epithelial ovarian cancer (EOC) has not significantly improved over sev...
Deregulation of chromatin architecture is emerging as a critical feature of carcinogenesis, and geno...
Cell fixation, permeabilization and antibody staining of could have adverse effects on the quality o...
RNAseq performed on isolated satellite cells from scERWT and scERKO mice SOURCE: Dawn Lowe (lowex017...
We created furin KO cells in three colorectal cancer cell lines (DLD1, HCA7 and HT29) using CRISPR-C...
Leukemia is caused by the accumulation of multiple genomic lesions in hematopoietic precursor cells....
Pgrcre/+Foxl2LsL/+ mice showed absence of corpus luteum in the ovary, thus the mice were infertile a...
p21-activated kinases (Paks) play an important role in oncogenic signaling pathways, and have there...
Somatic mutations in various epigenetic regulators, including histone methyltransferases KMT2C and K...
Fetal life is a crucial period for sexual reproduction when bipotential gonads differentiate into ei...
Natural killer (NK) cells are critical mediators of host immunity against infectious disease and can...
Naked mole-rat skin fibroblasts (NSF) produces vHMM-HA. Although NSF-HA has been shown to suppress N...
We explored the connection between C/EBP (CCAAT/enhancer binding protein ) and Wnt signaling in gut ...
We have performed modular analyses to decipher the global transcriptional response and capture a bre...
Recent advances in next generation sequencing (NGS) has revolutionized systems-based analysis of cel...
Peripheral blood samples were collected from subjects enrolled in the TrialNet study TN-09. This was...
Purpose: To understand the molecular mechanisms underlying the CTX synergization with antibody thera...
We show that the COMPASS family histone methyltransferase co-factor ASH2L is required in NPCs prolif...
Transcriptional control by gonadal hormone nuclear receptors is the foundation for sex-dependent phy...
The nuclear factor-kB (NF-kB) family of transcription factors is important for hematopoietic functio...
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
Although the hypothalamus functions as a master homeostat for many behaviors, little is known about ...
Glioblastoma (GBM) is the most aggressive brain tumor and resistant to current available therapeutic...
Remodeling of chromatin accessibility is necessary for successful reprogramming of fibroblasts to ne...
Purpose: To understand the molecular mechanisms underlying the CTX synergization with antibody thera...
Oocyte defects lie at the heart of some forms of infertility and could potentially be addressed ther...
We analyzed coding transcript abundance in fully differentiated, primary brown adipocytes from murin...
Here we show the transcriptome of lymph nodes draining from RABV vaccinated B6 mice and TLR7 KO mice...
A well-characterized mouse model of SSc involves daily subcutaneous injections of the antitumor anti...
The mechanisms underlying hepatoblastoma are not well defined. To address this, we generated transc...
Diversified neurons are essential for sensorimotor function, but whether astrocytes become specializ...
We provide here the alterations in gene expression profiles of 3T3-L1 cells, a validated model for a...
Gene expression is controlled by transcription factors (TFs) that consist of DNA-binding domains (DB...
Purpose: The goals of this study were to evaluate the effects of acid suppression on the brain trans...
Purpose: The goal of this study is to analyze the transcriptional pathways regulated by Fbxo22 and K...
Atherosclerosis is a focal disease that preferentially develop in the regions of atheroprone disturb...
We report the transcriptomes of adipocytes and SVCs derived from HFD-fed obese mouse epididymal adip...
The mouse trachea is thought to contain two distinct stem cell compartments that contribute to airwa...
Inhibition of BCR signaling through BTK inhibitor, ibrutinib, has generated a remarkable response in...
NSG mice were IP injected with 30mg/kg busulfan. The following day, mice received 1,000,000-3,000,00...
Glioblastoma stem cells were infected with lentivirus expressing a non-targeting (gRNA-LacZ) or SOCS...
Purpose: RNA-seq analysis of three memory OT-I cell subsets (from a Klrg1-Cre fate reporter mouse mo...
Using RNA sequencing technology, we compared specic changes in the transcriptomic proles in human fo...