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Abstract: Cellular senescence, an integral component of aging and cancer, arises in response to dive...
we report the discovery of migrasomal RNA. High-throughput deep sequencing was used to identifiy an...
We identified a BPH transcriptional signature that included 392 significantly differential expressed...
Stop codon readthrough (SCR) occurs when the ribosome miscodes at a stop codon. Such readthrough eve...
We performed a transcriptome-wide study to compare gene expression profiles of ECFC, human coronary ...
T follicular helper (Tfh) cells are essential for germinal center B cell responses; however, the mol...
Bulk RNA-seq heart left ventricle data from wild type and WWP2 gene mutant mice (after 28 days of an...
During gestation, sex hormones cause a significant thymic involution which enhances fertility. This ...
Mutations of Tbr1, a high-confidence ASD (autism spectrum disorder)-risk gene encoding the transcrip...
Preparation of sequencing libraries and sequencing analysis using Illumina HiSeq 3000 platform (50 b...
Acute erythroid leukemia (AEL) most commonly involves transformation of both the myeloid and erythro...
We previously identified Synbindin promoted gastric and colon cancer development by activating ERK o...
Over the past decade, there has been a 10X rise in the prevalence of autism spectrum disorder (ASD) ...
Background: High-throughput transcriptomics has matured into a very well established and widely util...
Gene expression changes in normal pancreatic ductal organoids were isolated from mice with inducible...
Characterizing the complex composition of solid tumors is fundamental for understanding tumor initia...
In the adult brain, epigenetic control of gene expression has important roles in the processing of n...
We identifed genes differentially expression in HGC27 cells withor without AFDN-DT overexpression SO...
To identify changes in splicing patterns following SRSF1 knockdown, RNA-sequencing was performed on ...
Long non-coding RNAs (lncRNAs) are critical regulators in cancer. However, the involvement of lncRNA...
Noncoding microdeletion in mouse Hgf disrupts neural crest migration into the stria vascularis, redu...
Despite the high frequency of musculoskeletal extremity trauma, little is known about the dynamics o...
RNA-seq analysis of KP and KPI lung adenocarcinoma cells. Analysis revealed activation of Wnt signal...
We applied a cell population transcriptomics strategy to sorted human memory CD8 T cells to define n...
Comparison of gene expression pattern profiles of bone derived Ezh2 heterozygous (Het) mesenchymal c...
To understand the role of YAP/TAZ during gliomagenesis, we compared the transcriptomes of control an...
Trastuzumab (Herceptin), a humanized monoclonal antibody targeting the extracellular domain of human...
We describe a critical role for Cdk6 in JAK2V617F+ MPN evolution. The absence of Cdk6 ameliorates cl...
The project was designed to figure out the role of microglia in brain inflammation (EAE model). The ...
In this study we want to map the gene expression profile of liver infected with Adenovirus, either t...
Since discovery of dimethyl sulfoxide (DMSO), it has been applied to the multidisciplinary studies f...
One of the factors involved in TNBC aggressiveness is HMGA1, a member of non-histone chromatin prote...
Specialized adult somatic cells, such as cardiomyocytes (CMs), are highly differentiated with poor r...
We report the application of RNA-seq analysis for high-throughput profiling of murine lungs infected...
Myocardial ischemia (MI) is the most common cause of heart failure (HF) in the United States. G prot...
We used the Functional intergenic repeating RNA element (Firre) locus - a conserved intergenic lncRN...
Liver cancer susceptibility varies between strains of experimental animal models due to multiple gen...
Postprandial hypoglycemia is a disabling complication of bariatric surgery. So far, no therapy exist...
Purpose: The goal of this study was to identify genes induced upon type I and II interferon response...
This experimental series concerns the position bias and extent of 3'-end choice in MCF7 cells after ...
The prevailing dogma that approximately 50% of our genome is junk DNA composed of transposable eleme...
We sought to describe in detail human MAIT cell activation using a transcriptomic approach to define...
RNAseq was performed on Glud1-deficient macrophages vs. WT macrophages sorted at baseline and at the...
Remodeling transcription by targeting bromodomain and extraterminal (BET) proteins has emerged as pr...
It is currently accepted that the human brain has a limited neurogenic capacity and an impaired rege...
We identify clearly distinct transcriptomic signatures between clear cells from the caput, corpus an...
The protein Glycine-N-Acyltransferase Like 1 (GLYATL1) is involved in detoxification of benzoate and...
Chronic CD8 T-cell stimulation in persisting infections or tumors can induce a stable gene expressio...
We disrupted the RNA binding region in endogenous ATRX and tested localization of ATRX, EZH2 and H3K...
Single nucleotide polymorphisms and locus amplification link the NF-B transcription factor c-Rel to ...
Deletion or mutation of SH2B1 (SH2-B, PSM) is associated with severe obesity and insulin resistance ...
In this study, we employed RNA-seq technology to identify the exact role of mTORC1 on -cell identit...
Bulk RNA sequencing of purified primary human microglia from superior temporal gyrus and cerebellum ...
Vincristine, oxaliplatin, and cisplatin are commonly prescribed chemotherapeutic agents for the trea...
Wnt/-catenin signaling is essential for intestinal stem cell homeostasis and aberrant activation of ...
Gene expression of transduced effector CD4+ T cells determined by RNAseq 7 days after LCMV Armstrong...
We are interested in whether peritoneal LCM are programmed by omental Wt1+ stroma (identified as PDP...
Background: Zinc-finger protein 750 (ZNF750) is a potential tumor suppressor in oral squamous cell c...
Purpose: the goals of this study are to characterize GC B cells elicited by neonatal immunization wi...
PLZF (promyelocytic leukemia zinc finger) is a transcription factor acting as a global regulator of ...
Langerhans cells (LC) represent one of the first lines of contact between the immune system and sexu...
The lack of rapidly progressive murine models reflecting the classical infantile disease in ARPKD in...
According to ample experimental evidence, decreasing protein synthesis by inhibiting mTORC1 increase...
Translation is a basic cellular process and its capacity is adapted to cell function. In particular,...
immortalized patient derived kidney epithelial cell were compared to cells exposed to ER stress (tha...
TRAP translational profiling is a method that allows investigators to genetically characterize speci...
Purpose: We have recently extablished a new protocol for the generation of inner ear organoid or Lgr...
Ligand binding induces extensive spatial reorganization and clustering of the EphA2 receptor at the ...
Purpose: To use next-generation sequencing (NGS) to dissect the human monocyte-CMV host-pathogen int...
We have expressed mouse Snai1, mutant Snai1 or empty vector in the HPC7 cell line and performed RNA ...
Background: The adult mammalian heart has limited capacity for regeneration following injury, wherea...
The A375, human BRAFV600E mutant melanoma, cell line (wildtype), two PTEN-null, BRAFV600E cell line...
Using 3-end RNA-seq followed by digital gene expression analyses we assessed genes that change expre...
Injuries to flexor tendons can be complicated by fibrotic adhesions, which severely impair the funct...
Nogo, also called RTN4, functions through three isoforms including Nogo-A, -B, and -C. Although Nogo...
Transcriptome analysis by high throughput sequencing SOURCE: Yusuke Tarumoto (ytarumot@cshl.edu) - ...
Using Sst and parvalbumin subtype-specific fluorescence activated cell sorting (FACS) and RNA sequen...
Innate lymphoid cells (ILCs) are tissue-resident lymphocytes subdivided into ILC1s, ILC2s and ILC3s ...
The effect of NF90 on transcript abundance was measured using RNA-seq. SOURCE: Rosemary KiernanGene ...
Cell-lineage specification is a tightly regulated process that is dependent on appropriate expressio...
To study the effect of LTbR induction on spleen and duodenum transcriptome, we performed RNA sequenc...
Chronic CD8 T-cell stimulation in persisting infections or tumors can induce a stable gene expressio...
Cytokines activate signaling via assembly of cell surface receptors, but it is unclear whether modul...
Lineage selective transcription factors (TFs) are important regulators of tumorigenesis, but their b...
Mutations in desmosome genes cause arrhyythmogenic cardiomyopathy (ACM). Using desmoplakin haploinsu...
We performed comprehensive analysis of host gene expression in MmuPV1 infected ear tissues with tumo...
In this study we tested the ability to predict organ injury endpoints from in vitro transcriptomics ...
To investigate the cooperative function KDM4D/NFIB/MLL1 complex in the regulation of adipogenic diff...
Hepatic iron overload is a risk factor for progression of hepatocellular carcinoma (HCC), although t...
Cachexia is a wasting syndrome characterized by pronounced skeletal muscle loss. In cancer, cachexi...
Neutrophils represent a fundamental mechanism of antimicrobial resistance and inflammation 1. Moreov...
Many studies have reported that human embryonic stem (hES) cells have an exceptional ability to repa...
To systemically study the molecular function of CARMIL3 in cancer cells, we used mammary tumor cells...
To elucidated through an unbiased manner which genes and pathways are differentially regulated durin...
In this study, we hypothesized that the effects of higher-order combinations of microbial stimuli ca...
We performed RNA sequencing to profile the temporal dynamics of gene expression during gliogenic NS/...
Though high frequency of Tregs in tumor obstructs anti-tumor immune responses, systemic depletion of...
Although there are many prospective targets in the tumor microenvironment (TME) of high-grade serous...
Arginine methylation is a common post-translation modification that is catalyzed by protein arginine...
Background: Degenerative disc disease (DDD) is a primary contributor to low back pain, a leading cau...