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Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Murine alternatively activated macrophages can exert anti-inflammatory effects. Expanding upon this...
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare lethal genetic disorder characterized with sym...
Purpose: The goals of this study are to compare NGS-derived U2OS transcriptome profiling (RNA-seq) T...
HGC27 gastric cancer cells were manipulated to express mutant p53 SOURCE: Osamu Kikuchi (okikuchi@br...
Translation is a basic cellular process and its capacity is adapted to cell function. In particular,...
The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite...
We identify nutrient engineering though the supplementation of amino aids to represent a novel tool ...
Transcriptomic profile of CD34+ cells circulating in peripheral blood of TCIRG1-mutated osteopetroti...
We compared the transcriptomes of control and YAP/TAZ knockout gliomaspheres derived from mouse newb...
In the adult brain, epigenetic control of gene expression has important roles in the processing of n...
We show that Spen, an Xist binding repressor protein essential for XCI, binds to ancient retroviral ...
Recent studies have revealed an essential role for embryonic cortical development in the pathophysio...
The scope of this project is to study, using state-of-the-art systems biology approaches integrating...
To identify mRNAs that are most translationally repressed following eIF4A inhibition and those that ...
The escalating prevalence of metabolic syndrome (MetS) poses significant risks to type 2 diabetes me...
Rheumatoid arthritis is an inflammatory disease of the synovial joints that affects ~1% of the human...
The goal of this experiment was to identify Rfx6-regulated genes in the ileum of adult mice by compa...
Mammary gland development is fueled by stem cell self-renewal and differentiation. External cues fro...
The Kaposi's sarcoma-associated herpesviruses causes several cancers including Kaposi's sarcoma and ...
We report a transcriptional response in the mouse bladder following exposure to the major flagella f...
Gata2, a zinc finger TF, is essential for the generation and survival of HSCs in the embryo and has ...
mRNA expression profiles from alpha-MHC-Cre X IRS1-flox, alpha-MHC-Cre X IRS2-flox, or IRS2-flox mou...
Bulk RNA sequencing of FACS sorted primary murine microglia from WT mixed glial cultures isolated fr...
51 healthy adults were vaccinated with seasonal influenza vaccine and PBMC were collected before and...
Pluripotent stem cells (PSCs) have increasingly been used to model different aspects of embryogenesi...
Mitotic bookmarking transcription factors (BFs) maintain the capacity to bind to their targets durin...
RNAseq data from blood and muscle was obtained to study the association of blood markers with diseas...
Deeper understanding of T cell biology is crucial for the development of new therapeutics. Human na...
Acute Myeloid Leukemia (AML) develops due to the acquisition of mutations from multiple functional c...
The chromodomain helicase DNA binding protein CHD8 is among the most frequently found de-novo mutati...
We report the effect of siRNA-mediated ABCE1 KD in HeLa cells, using a modified ribosome profiling p...
Despite effective strategies, therapy resistance in HER2+ breast cancer remains a challenge. While t...
Inorganic arsenic (iAs) is a widespread environmental toxin. In addition to being a human carcinogen...
Pien Tze Huang (PZH) is a traditional Chinese medicine which was widely utilized in Asia for hepatic...
The redox state of the neural progenitors regulates physiological processes such as neuronal differe...
Background: mRNA interactions with each other and other signaling molecules define different biologi...
The aim of the study was to compare the transcriptional profile of healthy skin Tregs to Tregs isola...
The transcription factor FOXM1 is up-regulated and overexpressed in aggressive, therapy-resistant fo...
Animals deficient for the alpha subunit of the large conductance calcium dependent potassium channel...
To promote the development and understanding of the in vitro erythroleukemia model, we analyzed the ...
Total RNA sequecing for human induced pluripotent derived cerebral organoids from healthy controls a...
The hypothalamus is a central regulator of many innate behaviors that are essential for survival, bu...
To investigate how Roquin regulates cellular transcripts during Human cytomegalovirus (HCMV) infecti...
The goal of this study was to compare expression profiles of B cells in the presence and absence of ...
A single cell suspension was generated from B3-adrenergic agonist (CL; 1 mg/kg/day) for 4 days and s...
Developmental cell fate specification is a unidirectional process that can be reverted in response t...
Exposure to UVB irradiation results in multitude of cellular responses including generation of react...
Single-cell RNA-sequencing was performed in the mouse and naked mole-rat immune systems in order to ...
Bulk RNA-seq of highly pure regionally specified human pluripotent stem cell-derived astrocytes SOUR...
Total RNA-Seq of Human adipose tissue were sequenced on the Illumina HiSeq4000 platform SOURCE: Laur...
Rapid and widespread mRNA decay is a previously unappreciated feature of apoptosis. Previous work sh...
Within mammalian nuclear space, chromosomes are hierarchically folded into active (A) and inactive (...
The aim of the current study is to characterize the global alternative splicing profiles associated ...
T regulatory (Treg) cells maintain immunological tolerance and their depletion in humans and mice re...
Suppression of retrotransposons is an integral part of germline genome defense. The PIWI-associated ...
We report RNAseq analysis on RNA from e9.5 hearts of Asb2 mutant and Asb2.Flna double mutants with c...
Histone chaperone FACT is commonly expressed and essential for the viability of transformed but not ...
Alternative splicing (AS) occurs in nearly all human genes and abnormal AS has a close connection wi...
Molecular chaperones such as heat-shock proteins (HSPs) help in protein folding and complex assembly...
We have analyzed the global gene expression modulation induced by mechanical stress (shear stress) o...
We report the application of single-molecule-based sequencing technology for high-throughput profili...
The lincRNA-NR_033736 is an early-primary gene controlled by the type I IFN signaling in murine inte...
We performed RNAseq analysis to determine the effect of MFN2 deletion on oocyte global gene expressi...
Damaged tissues have increased risk of cancer development through poorly understood mechanisms. In t...
Bulk RNA-Seq of all epithelial cell populations from both 2D-Gelatin and 3D-Matrigel conditions, nam...
Radioresistance has remained the major cause of local relapse and distant metastasis in lung cancer....
Two subpopulations of low density granulocytes (LDGs) were defined in terms of different gene expres...
NFkB RelA is the potent transcriptional activator of inflammatory response genes. We stringently def...
RNA-seq data of primary hematopoietic progenitor cells from -77 knockout mice which expressing Gata2...
Animals deficient for the alpha subunit of the large conductance calcium dependent potassium channel...
RNA sequencing for 6 samples SOURCE: Lin Wang Shanghai Pulmonary Hospital
Spermatogenesis is a complex process of sperm generation, including mitosis, meiosis, and spermiogen...
Abstract: Annual administration and reformulation of influenza vaccines is required for protection a...
Purpose: to examine the early transcriptional responses to stimulation in Jurkat E6.1 cells, and the...
Here we investigate the essentiality of lysine acetyltransferase KAT7 in AMLs driven by the MLL-X fu...
The Tousled like kinases 1 and 2 (TLK1/2) control histone deposition through the ASF1 histone chaper...
Coeliac disease (CeD) is a complex, polygenic inflammatory enteropathy with autoimmune features caus...
The escalating prevalence of metabolic syndrome (MetS) poses significant risks to type 2 diabetes me...
RNA-seq was performed to identify genes affected by CRISPRi (dCas9-KRAB) with sgRNA (sgTGFB1_B9D2) t...
USP21 belongs to ubiquitin specific protease (USP) family. To dissect the molecular mechanisms that ...
Matched high-grade serous ovarian carcinoma samples collected from the ovary (ov), omental metastasi...
A transitory, interleukin-25-responsive, KLRG1high Group 2 innate lymphoid (ILC2) cell subset that m...
Tumor cells were observed to undergo extravasation through intrivital imaging and immediately follow...
Chromatin immunoprecipitation sequencing of H3K4me2, H3K27ac as well as, ATACseq and RNA-seq reveals...
Sarcoidosis is a systemic inflammatory disease characterized by infiltration of immune cells into gr...
Regenerating new alveolar epithelium is essential for recovery from many lung diseases. This multi-c...
In mammals, the acquisition of the germline from the soma provides the germline with an essential ch...
Influenza A virus (IAV) causes a wide range of extra-respiratory complications, ranging from central...
Proinflammatory cytokines are important mediators of pancreatic beta cell dysfunction and demise in ...
Proanthocyanidins (PAs) that are naturally occurring compounds have shown the potential chemoprevent...
GFP-PR28 homozygous mice show decreased survival time, while the heterozygous mice show motor imbala...
We report the application of next generation sequencing for evaluating alternative splicing (AS) eve...
To investigate the altered gene expression levels in MSR1 knockout and wild type macrophages in co-c...
Males were placed onto an all liquid diet with gradually increasing amounts of ethanol as follows: ...
Modeling the processes of neuronal progenitor proliferation and differentiation to produce mature co...
The progressive loss of midbrain (MB) dopaminergic (DA) neurons defines the motor features of Parkin...
Gene expression changes were compared in proliferating and senescent human IMR90 cells, with either ...
Zellweger spectrum disorders (ZSD) are inborn metabolic diseases cause by genetic alterations in PEX...
Protein translation depends on mRNA-specific initiation, elongation, and termination rates. While th...
We employed RNA-seq to map the transcriptome of human MRC5 fibroblasts during HCMV infection with AD...