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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
We developed a technique for generating hypothalamic neurons from human pluripotent stem cells. Here...
The goal of this study is to investigate if interferon signaling regulates immune checkpoint blockad...
Resolution of early molecular events preceding endogenous OCT4 activation is critical to understandi...
The histone deacetylase HDAC2, which negatively regulates neuronal plasticity and synaptic gene expr...
Transcriptional profiling of conventional and novel CD8 T cell subsets using RNA sequencing SOURCE: ...
Aneuploidy, a state of karyotype imbalance, is a hallmark of cancer. Changes in chromosome copy numb...
To identify glioma-related RNAs, we used four glioma patients' fresh tumor tissues and normal tissue...
Mutations in the RNA-binding protein, RBM10, result in a human syndromic form of cleft palate, terme...
In order to determine the imprinted transcription factor Zac1 targets, we overexpressed Zac1 in a mo...
We reported that skeletal muscle insulin sensitivity was restored to a lean phenotype with exercise ...
To determine how the transcription factors GR and STAT3 cooperate to regulate gene expression, the M...
As the major histone H3K4 methyltransferases in mammals, the Set1/Mll complexes play important roles...
Coding and long non-coding RNA metabolism is now revealing its crucial role in Amyotrophic Lateral S...
Atopic dermatitis (AD) is a common chronic skin disease, affecting >15% of children and 2-10% of adu...
RNA was extracted from duodenal villi from crontrol and Prdm16 KO mice 3 days after deletion SOURCE:...
How progenitor cells regulate quiescence and differentiation is poorly understood. Here, we demonstr...
Single human lung epithelial cell transcriptomes, isolated and processed via Fluidigm C1 SOURCE: And...
Systemic lupus erythematosus (SLE) is often considered a disease driven by autoreactive B cells and ...
ARID1A is frequently mutated in ovarian clear-cell carcinoma (OCCC) and often co-exists with activat...
B lymphocyte development is often depicted as a linear process that initiates in the fetus and conti...
We analyzed the transcriptomic differences of cultured mouse spermatocytes (GC2 cells) stably transf...
Granulomas are immune cell aggregates formed in response to persistent inflammatory stimuli. Granulo...
We used RNA-Seq assay to characterize AMPK-regulated gene expression patterns and then compared with...
Regulatory T (Treg) cells, expressing abundant amounts of the IL-2 receptor (IL-2R), are reliant on ...
Sigle cell RNAseq for human female embryonic stem cells and the differentiated cells by BMP4 treatme...
RNAseq analysis was performed on liver of tet-YAP and tet-Myc transgenic mice induced for 2 days (...
This study aimed to quantify and compare the mRNA abundance of all major XPGs in liver and intestine...
Human endometrial glands from early, mid and late secretory phases were captured using laser microdi...
Progressive organ fibrosis accounts for one third of all deaths worldwide, yet preclinical models th...
Stress granules are mRNA-protein assemblies formed on nontranslating mRNAs. Stress granules are impo...
Fungal infections are major causes of morbidity and mortality, especially in immunocompromised indiv...
Purpose: The goal of this study was to assess gene expression changes in TPR50 Tau transgenic mice. ...
Purpose: CUGBP1 is an important regulator of liver homeostasis, through splicing regulation, stabili...
Cancer genomes are characterized by focal increases in DNA methylation, co-occurring with widespread...
During development, two cell-types born from closely related progenitor pools often express the iden...
This study aimed to interrogate the interrelationship between 3D genome organization and global gene...
To study the role of estrogen receptor alpha (ER) in T cell mediated inflammation, colitis was induc...
Metabolic production of acetyl-CoA has been linked to histone acetylation and gene regulation, howev...
RNA-seq of RNA isolated form costal chondrocytes of mice at post-natal day 7 SOURCE: David Young (da...
Bone morphogenetic protein 4 (BMP4) plays an important role in cancer pathogenesis. In breast cancer...
The goals of this study are to define the putatitve impacts of FXRalpha deficiency in testicular phy...
The mammalian male germline is sustained by a pool of spermatogonial stem cells (SSCs) that can tran...
Hutchinson-Gilford progeria syndrome (HGPS) is an ultrarare and fatal disease with features of prema...
We previously established the transcription factor Zfp423 is critical for maintaining white adipocyt...
SETD5 gene mutations have been identified as a frequent cause of idiopathic intellectual disability....
We report our results of RNA-seq analysis on freshly isolated, sorted subsets of cytotoxic lymphocyt...
mRNA quality control mechanisms ensure fidelity of protein translation. An evolutionarily conserved ...
Super-enhancers (SEs) are large genomic regions with high density of enhancer marks. In cancer, SEs ...
Background: Examining transcriptional regulation by existing antidepressants in key neural circuits ...
We sequenced mouse incisor mRNA from one-month-old Gli1-CreER;tdT and Axin2-CreER;tdT mice to compar...
Tissue resident macrophages are functionally diverse cells that share an embryonic mesodermal origin...
We sequenced mRNA in vastus lateralis muscle samples from two amateur endurance-trained men (V 2max ...
We have developed a computational approach that uses self-organizing maps for integrative genomic an...
Cancer cells must evade immune responses at distant sites to establish metastases. The lung is a fre...
A high degree of cell plasticity seems to promote malignant tumour progression, and an epithelial-me...
The fusion transcription factor PAX3-FOXO1 drives oncogenesis in a subset of rhabdomyosarcomas, howe...
We used RNA-seq to inquire gene expression profiles of lipomas with HMGA2-fusions and without gene f...
Kaposis Sarcoma herpesvirus (KSHV), an oncogenic virus, modulates host cell signaling and metabolism...
The goal of this study is to compare the transcriptome of mouse beta-cells expressing mutant constit...
Expression analysis in HepG2 and IMR90 cells in presence of Fluc siRNA or sPom121 or Nup98 siRNA SOU...
RNA-seq analysis of with known quantity of cell numbers and reference RNA (ERCC) to determine absolu...
COP1 regulates MAP kinase dependent stability Pea3 transcription factors. We determined the role of ...
In this study, we assess potential differences in mechanism of action for two PAHs, benzo[a]pyrene (...
Biallelic defects of the gene encoding for the intracellular enzyme 3 repair exonuclease (Trex)1 cau...
A specific missense mutation in the DNA binding domain of HNF4A, R85W, causes Fanconi renotubular sy...
ASXL1 is frequently mutated in a spectrum of myeloid malignancies with poor prognosis. Loss of Asxl1...
The lineage of wild-type horizontal basal cells (HBC) stem cells from the olfactory epithelium were...
In this study, we performed RNA-Seq studies to generate a transcriptomic cohort containing UV-respon...
RNA-seq analysis of 16 B6J x B6NJ-F2 mice which are homozygous for either the wild-type B6J allele (...
We performed RNA sequencing to produce expression quantitative trait loci (eQTL) database of Crohn's...
Organoid formation is critical to the progress of regenerative medicine. We use the formation of ski...
In the mammalian cortex, about 60% of GABAergic interneurons, mainly including parvalbumin-expressin...
Using a targeted Gtf2ird1 knockout mouse, we employed massively-parallel sequencing of mRNA (RNA-Seq...
While multiple myeloma patient prognosis has improved over the past decade, research towards discove...
Identification of NANOG transcribed factors during the establishment of pluripotency SOURCE: Catheri...
Trascriptome analysis of aml samples were performed SOURCE: Nuri,Alpay,Temiz University of Minnesota
RAS is frequently mutated in multiple myeloma (MM) leading to aberrant signaling. Next to their clas...
We examined transcriptome-wide effects of pertrurbation in KLF10 function (siKLF10) on TGF-regulated...
We studied the transcriptomics of pancreatic ductal adenocarcinoma (PDAC) and the role of a splicing...
Execution of pluripotency requires progression from the nave status represented by mouse embryonic s...
We measured changes in gene expression in MCF7 with CDK4/6 and AP-1 inhibition by abemaciclib and SR...
We used RNA sequencing to characterize gene expression of CD4+ CD8+ double positive (DP), Foxp3+ Tre...
Platelets are anucleate cytoplasmic fragments that lack genomic DNA, but continue to synthesize prot...
We performed regular RNA-seq to understand G1 cyclins function in ES cells SOURCE: Lijun Liu (lljuna...
The tumor suppressor protein 53BP1, a pivotal regulator of DNA double-strand break (DSB) repair, wa...
We utilized the stranded RNA-seq and small RNA-seq to identify and quantify RNA editing events locat...
In order to identify genes that are highly expressed in human IMA, we performed mRNA-seq analysis us...
The goal of this study was to generated and transcriptionally analyze purified populations of Phelan...
Aging improves pancreatic -cell function in mice. This is a surprising finding since aging is typica...
RNA-sequencing was performed to gain insight into the mechanism responsible for the apoptosis and ce...
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal deme...
Purpose: Identify new targets in MYCN-amplified Neuroblastoma; Methods: Kelly and LAN-1 neuroblasto...
In order to elucidate the developmental origin of oligodendrocyte precursor cells (OPCs) and get a b...
Imbalances in endoplasmic reticulum (ER) proteostasis are associated with etiologically-diverse dege...
In this study, we elucidated differential gene expression between transformed and untransformed muri...
Epigenetic heterogeneity is emerging as a significant phenotypic feature of tumors. In diffuse large...
Context: Long non-coding RNAs (lncRNAs) regulate pathological processes, yet their potential roles i...
The transcription factor STAT5 is fundamental to the mammalian immune system. However, the relations...
In mammals body temperature fluctuates diurnally around a mean value of 36-37C. Despite the small di...
Faithful execution of developmental programs relies on the acquisition of unique cell identities fro...