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Sequencing-based assays (Page 6)
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GSE68358: RNA-seq in two ER+ breast cancer cell lines with and without progestins
Exploring effect of progesterone/progestin treatment on gene expression SOURCE: Silvia Halim Cancer ...
GSE123992: Gene expression signatures of SATB2-defficient vs wild-type adult neocortex
During CNS development, the nuclear protein SATB2 is expressed in superficial cortical layers and de...
GSE70497: Effect of Bmal1 post-natal knockout on liver gene expression: time-series
Gene expression in the liver has been studied extensively in normal mice, but not in mice with circa...
GSE65808: Combining ChIP-Seq and RNA-Seq data in early placental development to study trophoblast invasion [RNA-Seq]
The placenta is an understudied organ that has a critical role in mammalian development. In early pl...
GSE141663: RNA sequencing from the microglia of mice with acute GvHD against syngeneic bone marrow transplanted and untreated controls
Understanding the role of myeloid cells in GvHD of CNS. Microglia are the major immune cells of the ...
GSE70580: Single cell RNA-sequencing of human tonsil Innate lymphoid cells (ILCs)
Single cell RNA-sequencing of human tonsil Innate lymphoid cells (ILCs) from three independent tonsi...
GSE149121: Single-Cell RNA-seq immune profile of normal and inflammed mouse skin
Comparison of mouse immune cells from skin treated with oxazolone or imiquimod SOURCE: Jeffrey,B,Che...
GSE99957: T Cell Expression of AhR Inhibits the Maintenance of pTreg Cells in the GI Tract in Acute GvHD
Transcriptome analysis of murine T cells pre- and post-transplant. SOURCE: Jonathan,S,Serody (jonath...
GSE106871: Analysis of the Clustered Protocadherin (cPcdh) Locus in Human and Mouse Pluripotent Stem Cells (RNA-Seq)
We provide a series of chromatin and transcriptomic profiles to establish the identity of the stocha...
GSE71635: Expression profiling of fetal mammary cells
We use RNA-sequencing to generate gene expression profiles of fetal mammary cells with unique sortin...
GSE69652: Dichloroacetate (DCA) prevents cisplatin-induced nephrotoxicity without compromising its anti-cancer properties.
The aim of this study was to compare the transcriptional changes that occur in the kidneys of mice a...
GSE68789: Distinct murine mucosal Langerhans cell subsets develop from pre-DCs and monocytes
Langerhans cells (LCs) populate the mucosal epithelium, a major entry portal for pathogens, yet thei...
GSE71299: Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities
SRSF2 is an RNA binding protein that plays important roles in splicing of mRNA precursors. Mutations...
GSE68818: RNA-seq gene expression profiling in resting murine B cells from WT or KMT2D knockout mice, before and after stimulation with LPS, IL4, and anti-CD180
Resting B cells were isolated from WT or KMTD KO mice by immunomagentic depletion of with anti-CD43 ...
GSE67902: Regulation of protein translation during mitosis
Entry into and exit from mitosis is driven by precisely-timed changes in protein abundance, and invo...
GSE67931: Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation
A key function of Na+/H+ exchanger regulatory factor 2 (NHERF2) is spatial organization of signaling...
GSE71028: Molecular distinctions between proprioceptors supplying Tibialis anterior (TA) and Gastrocnemius (GS) muscles [RNA-Seq]
Muscle-specific populations of proprioceptive sensory neurons form selective connections with spinal...
GSE70061: Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq
To identify HNRNPA2B1 binding sites on endogenous nuclear RNAs, we performed HITS-CLIP for endogenou...
GSE67945: Investigation about fibroblasts of different origins in culture
The goal of this study was to determine if fibroblasts from different origin (skin, colon, tumors) w...
GSE79499: LncRNA expression profiling of the early mesoderm reveals LncCPR as a novel regulator of cardiogenesis in mice
Whole mount in situ hybridization analysis of the 17 lncRNAs revealed that lncRNAs 2410006H16Rik and...
GSE68462: RNA sequencing expression analysis of murine Tet-off MLL-AF9;NRAS acute myeloid leukemia cells over-expressing Id2 and upon MLL-AF9 withdrawal
We investigated the role of the transcriptional regulator Id2 in the context of MLL-rearranged acute...
GSE68846: RNA sequencing of ILK-deficient hair follicle bulge stem cells
We sequenced mRNA from FACS purified hair follicle bulge stem cells from 21 d old control and ILK-de...
GSE113524: A Paradigm Shift in Alzheimer's Disease Precipitation, Progression and Potential Prevention
De novo mutated ADNP is a most prevalent gene driving syndromic autism with intellectual disability....
GSE65697: Genome-wide transcriptome profiles in pluripotent mouse Embryonic Stem Cells and during Retinoic Acid-induced differentiation
We report the genome-wide RNA expression levels in pluripotent mESC and as mESC differentiate toward...
GSE71434: Allelic reprogramming of the histone modification H3K4me3 in early mammalian development
Histone modifications are considered as fundamental epigenetic regulators that control many crucial ...
GSE105486: APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division
Asymmetric cell division results in two distinctly fated daughter cells to generate cellular diversi...
GSE69889 (human): Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk
The molecular clock is a transcriptional oscillator present in brain and peripheral cells that coord...
GSE68083: TAF10 interacts with the GATA1 transcription factor and controls mouse erythropoiesis
We have ablated TAF10 in the erythroid compartment only by crossing the TAF10lox mice with the EpoR-...
GSE75077: Whole genome transcriptomic experiments in mice heart development system
In order to understand genes expressed during posterior second heart field (pSHF) development, we pe...
GSE69940: Genome-wide analysis of embryonic gene epression in the absence of Prox1 compared to wild type
Overview: We report here that gene expression in E13.5 wild type (WT) mouse lenses differs from the...
GSE65818: Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development
Alternative splicing (AS) generates vast transcriptomic complexity in the vertebrate nervous system....
GSE122710: Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-1, with DMSO or ML290 (5 M) for 72h.
The overall aim of this experiment was to identify specific genes and molecular pathways regulated b...
GSE71446: Genome-wide Analysis of Human Constitutive Androstane Receptor (CAR) Transcriptome in Wild-type and CAR-knockout HepaRG cells
The constitutive androstane receptor (CAR, NR1I3) modulates the transcription of numerous genes invo...
GSE68538: CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation
We have developed EMD- and BM-prone and defined the presence of an EMT-like mRNA signature in both E...
GSE118859: SOX2 epidermal overexpression promotes cutaneous wound healing via activation of EGFR/MEK/ERK signaling mediated by EGFR ligands
We perfomed RNA-seq and wound healing analysis to identify the mechanism how SOX2 promote wound heal...
GSE68461: RNA sequencing analysis of murine MLL-AF9 acute myeloid leukemia cells expressing different levels of Id2 and Kit
We investigated the role of the transcriptional regulator Id2 in the context of MLL-rearranged acute...
GSE68108: Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells
Hepatic stellate cells are the primary cell type responsible for development of fibrosis in chronic ...
GSE70544: Transcriptional Signatures of Hypoxic and Inflammatory Renal Epithelial Injury
To identify RNA transcripts involved in acute and chronic renal epithelial injury, we performed unbi...
GSE67681: HDAC Inhibition Impedes HMGA2-controlled Epithelial-Mesenchymal Plasticity and Suppresses Metastatic, Castration-Resistant Prostate Cancer (RNA-seq)
To study the dynamic regulation of the Epithelial-Mesenchymal Transition (EMT), we developed genetic...
GSE71364: RNA-seq analysis of the DTA-injured retina
The goal of this study is to identify genes upregulated in the DTA-injured retina.; ; Methods: Retin...
GSE66954: Tracing the formation of hematopoietic stem cells in mouse embryos by single-cell functional and RNA-Seq analyses [10-cell]
Hematopoietic stem cells (HSCs) in adult are specified early from the endothelium-derived precursors...
GSE70788: RNA sequencing of Control, Cop1, Cop1 and Cop1 ETV1/4/5 islets
Identify genes which are differentially expressed in Cop1 compared to control islets and are also s...
GSE125223: Paradoxical CD4 decline on ART: a novel, rare and perplexing immunologic outcome
The goal of antiretroviral therapy (ART) is to suppress HIV-1-replication and reconstitute CD4-T-cel...
GSE68178: hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function
We profiled the gene expression/splicing program of normal and hnRNP U-deficient mouse hearts by RNA...
GSE69687: Wnt addiction of genetically defined cancers reversed by PORCN inhibition
Enhanced sensitivity to Wnts is an emerging hallmark of a subset of cancers, defined in part by muta...
GSE80591: Messenger RNA expression after MK2206/DMSO treatment of T47D cells
We performed RNA-seq in T47D cells after 24 hour treatment with the AKT inhibitor MK2206 or DMSO. We...
GSE70602: Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma
RNA sequencing libraries were made for A-498 and 786-O to detect the transcripts regulated by the li...
GSE70069: Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation [RNA-seq]
The histone 3 lysine 9 methyltransferase Setdb1 is essential for both stem cell pluripotency and ter...
GSE70798: Single cell transcriptomic analysis of thymic epithelial cells
Single cell transcriptomic analysis of wildtype and AireKO thymic epithelial cells SOURCE: CBDM Lab ...
GSE118005: SNON and Arkadia (RNF111) regulate TGF-SMAD2/3 dose-dependent responses
The purpose of this RNA-seq experiment was to identify Activin A target genes that were differential...
GSE86618: Single Cell RNA-Sequencing Identifies Diverse Roles of Epithelial Cells in Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease causing alveolar remodelin...
GSE85098: Expression data from AEG-1fl/fl and AEG-1DHEP mice which have conditional hepatocyte-specific knockout of AEG-1 (Astrocyte elevated gene 1)
AEG-1 is overexpressed in human hepatocellular carcinoma (HCC) and positively regulates development ...
GSE71209: Genes Targeted by the Hedgehog-Signaling Pathway can be Regulated by Estrogen Related Receptor
We report Hedgehog signaling responsive genes with or without Esrrb in NI3T3 cells.; Using Hh-respon...
GSE72156: Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A
RNA-Seq analysis of SSA treated cells SOURCE: Rei YoshimotoDivision of Gene Expression Mechanism Fuj...
GSE66978: Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
Early B cell development is orchestrated by the combined activities of the transcriptional regulator...
GSE71511: ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq]
Genes encoding subunits of SWI/SNF chromatin remodeling complexes are collectively mutated in ~20% o...
GSE71176: Genome-wide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo [RNA-Seq]
The tumor suppressor p53 is a transcription factor that coordinates the cellular response to DNA dam...
GSE71740: Inhibitors of the histone lysine demethylase KDM1A are broadly efficacious in AML by evicting the enzyme from chromatin [RNA-Seq]
Investigating the effects of two different classes of KDM1A inhibitors on the transcriptome of AML c...
GSE71873: Genome-wide analysis of gene expression using in vitro cultured control and Lats1/2 deficient hepatoblasts [RNA-Seq]
RNA-sequencing results with in vitro cultured control and Lats1/2 deficient hepatoblasts, in vitro d...
GSE70503: Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines
Variation in the expression level and activity of genes involved in drug disposition and action (pha...
GSE73189: Select correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis
We report abonormally expressed genes of idiopathic interstitial pneumonia by RNA-seq analysis. BMP3...
GSE71453: Single cell RNA-seq analysis of sensory neurons reveal diverse injury responses after sciatic nerve transection
We reported the gene expression analysis of different types of sensory neuron with peripheral nerve...
GSE67955: The landscape of global-long range interactions in mouse and human blood cell lines mediated by Yy1, GATA1, and CTCF during differentiation
Abstract: A network of interactions between functional DNA elements regulates gene expression in a p...
GSE71145: Cellular response to proteasome inhibition by Bortezomib
Analysis of the coordinated transcriptional reponse to proteasome inhibition SOURCE: Thomas Wandless...
GSE96764: Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis
Extracellular signaling and nutrient availability are major factors for cell fate decision. Responds...
GSE70588: ADAR2 affects mRNA coding sequence edits but not gene expression or splicing in vivo
Adenosine deaminases (ADARs) are RNA binding proteins that bind to double stranded RNA and convert a...
GSE71075: Splicing analyses of 46C mESCs following PTBP depletion
PTBP1 and PTBP2 control alternative splicing programs during neuronal development, but the cellular ...
GSE75192: Deep sequencing of mRNA from mouse at five different timepoints in three different tissues (brain, liver, skin)
Comparison of temporal gene expression profiles; ; Jena Centre for Systems Biology of Ageing - JenAg...
GSE70833: HCT116 MYC 3' TBE1 (WT) and KO RNA-Seq
mRNA was sequenced from HCT116 MYC 3' TBE1 (WT) and KO cells to identify genes differentially expres...
GSE66931: Single cell RNA-Seq of Hira-KO and control MII oocytes [Gdf9-Cre+]
The integrity of chromatin, which provides a dynamic template for all DNA related processes in eukar...
GSE71534: Mechanisms of Fibrotic Aortic Valve Stenosis
To examine molecular mechanisms of aortic valve stenosis in mice with hypertension and hypercholeste...
GSE75147: RNA splicing alteration on glioblastoma and normal neural stem cells
We identified PHF5A as a functional synthetic-lethal hit in glioblastoma stem cells compared to norm...
GSE66345: A Circult Mechanism for Differentiating Positive and Negative Associations
The ability to differentiate stimuli predicting positive or negative outcomes is critical for surviv...
GSE71531: Targeting leukemia-initiating cells through pharmacologic inhibition of Pol I transcription to treat MLL-driven acute myeloid leukemia
Transcriptome analysis revealed differential responses to Pol I inhibition in p53WT and p53null AML ...
GSE72111: Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells
Purpose: To identify downstream signaling pathways that mediate functions of GALNT14; Methods: RNAs ...
GSE71541: Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines
The expression profile in miR-155-/- FLT3-ITD+ AML is unknown. Using empty vector (EV) or two distin...
GSE72207: RNA-seq of Chd7 wild type and mutant granule neuron progenitors
We identified genes that are regulated by Chd7 in GNPs SOURCE: Weijun Feng DKFZ
GSE75168: Histone H3 lysine 4 acetylation-methylation dynamics define breast cancer subtypes [RNA-seq]
The onset and progression of breast cancer are linked to genetic and epigenetic changes that alter t...
GSE71773: Omega-3 fatty acids partially revert the metabolic gene expression profile induced by long-term calorie restriction
Calorie restriction (CR) consistently extends longevity and delays age-related diseases across sever...
GSE75187: Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia [RNA-Seq 2]
Understanding the specific cell populations responsible for propagation of leukemia is an important ...
GSE73238: Impact of Tcf1 and Lef1 deficiency on mature CD8 thymocytes
Comparison of transcriptome between control and Tcf1/Lef1-deficient mature CD8 thymocytes SOURCE: Ha...
GSE75826: Expression dynamics, relationships, and transcriptional regulations of diverse transcripts in mouse spermatogenic cells
We were interested in how the complex mammalian transcriptomes were established. Using spermatogenes...
GSE98428: mRNA Sequencing of Human PromoCells Using Random Primed mRNA-Sequencing Technique
The differential gene expression of human cardiomyocytes induced by kinase inhibitors sorafenib and ...
GSE116239: Bulk RNA-seq of foamy and non-foamy intimal macrophages from ApoE -/- mouse
Macrophages in atherosclerotic aorta are major population in lesion and contributes to lesion format...
GSE71554: Expression profiling for mouse embryonic stem cells deficient for Smad1 and Smad5 or for Bmp activated subpopulations.
In this study we determine the transcriptional profile by RNAseq of mESC in the absence of Smad1 and...
GSE75185: Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia [RNA-Seq 1]
Understanding the specific cell populations responsible for propagation of leukemia is an important ...
GSE77795: Effect of Ppargc1a overexpression in mouse heart
Ppargc1a overexpression in heart tissue measured using RNA sequencing SOURCE: Merja Heinäniemi unive...
GSE72379: Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq]
To better understand transcriptional regulation during human oogenesis and pre-implantation embryoni...
GSE72761: RNAseq analysis of the duodenum of intestine-specific adult Nkx2.2 mutant mice
Aim: Transcriptional analysis of the duodenum of adult Nkx2.2flox/flox;Villin-Cre (Nkx2.2int) mice v...
GSE75209: Simultaneous pathway activity inference and global gene expression analysis using RNA-sequencing [halofuginone]
Bone marrow derived macrophages treated with small molecules and stimulated with LPS SOURCE: Raivo K...
GSE106384: Transcript analysis of CD45+Ter119+CD71+ erythroid-like progenitor cells from tumor-bearing mice
We report the application of RNA sequencing technology for high-throughput profiling of transcriptom...
GSE74977 (mouse): The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin
Hemoglobinopathies, including sickle cell disease and _-thalassemia, are global public health concer...
GSE79696: Circadian Epigenomic Control of Skeletal Muscle Fuel Metabolism by HDAC3
We address the function of HDAC3 in skeletal muscle metabolism SOURCE: Bin Fang (binfang@mail.med.up...
GSE75074: Pregnacy-induced regulation of islet proteins
We report pregnacy-induced changes at the RNA level using RNAseq SOURCE: Jeannette,Schlichting,Kirke...
GSE76511: Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state
Innate sensing of viruses by dendritic cells (DCs) is critical for the initiation of anti-viral adap...
GSE73175: RNA sequencing of primary thymic, bone and skin mesenchymal cells
Purpose : Elucidate post-natal role of SCA1+ thymic mesenchymal cells (tMCs) and evaluate the functi...
GSE71794: Notch Activation Confers Enhanced Lymphoid Potential in Murine ESC/iPSC-derived HSC and Reconstitutes Adaptive Immunity In Vivo [RNA-Seq]
Hematopoietic stem cell (HSC) transplantation has the potential to cure blood disorders but is limit...
GSE129493: Functional robustness of spermatogonial stem cells after induction of hyperactive Hras
We report on gene expression in stem cell-enriched, undifferentiated spermatogonia isolated from the...
GSE71595: RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients
Through RNA sequencing of CD4+ Tmemory/effector cells derived from the synovium of JIA patients and ...
GSE68284: Next Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes [RNA-Seq P21]
Purpose: This study was carried out to determine the consequences of the Rfx2-/- genotype on spermat...